| REGN | Regeneron Pharmaceuticals Inc | $40.87B | +96402.48% |
| VRTX | Vertex Pharmaceuticals Inc | $26.48B | +62436.95% |
| BNTX | BioNTech SE | $21.10B | +49713.64% |
| RPRX | Royalty Pharma plc - Class A | $19.82B | +46689.65% |
| GMAB | Genmab | $12.38B | +29122.67% |
| JAZZ | Jazz Pharmaceuticals plc | $11.86B | +27903.78% |
| MRNA | Moderna Inc | $11.49B | +27026.33% |
| ARGX | Argen X SE | $8.68B | +20402.24% |
| BMRN | Biomarin Pharmaceutical Inc | $8.59B | +20185.75% |
| ONC | BeiGene Ltd | $8.55B | +20097.45% |
| SVA | Sinovac Biotech Ltd | $8.54B | +20069.36% |
| INCY | Incyte Corp | $7.34B | +17229.66% |
| ROIV | Roivant Sciences Ltd | $5.71B | +13379.78% |
| ALNY | Alnylam Pharmaceuticals Inc | $4.97B | +11626.87% |
| AAPG | Ascentage Pharma Group International | $3.97B | +9265.06% |
| IONS | Ionis Pharmaceuticals Inc | $3.45B | +8046.33% |
| GLPG | Galapagos NV | $3.41B | +7940.30% |
| PCVX | Vaxcyte Inc | $3.35B | +7806.28% |
| SRPT | Sarepta Therapeutics Inc | $3.18B | +7406.34% |
| PTCT | PTC Therapeutics Inc | $2.87B | +6674.74% |
| CRSP | CRISPR Therapeutics AG | $2.73B | +6336.41% |
| FTRE | Fortrea Holdings Inc | $2.68B | +6236.25% |
| HALO | Halozyme Therapeutics Inc | $2.67B | +6211.02% |
| NBP | NovaBridge Biosciences. | $2.61B | +6069.93% |
| EXEL | Exelixis Inc | $2.59B | +6024.19% |
| TECH | Bio-Techne Corp | $2.55B | +5922.67% |
| ENLV | Enlivex Therapeutics Ltd | $2.33B | +5394.68% |
| ARWR | Arrowhead Pharmaceuticals Inc | $2.27B | +5256.00% |
| RVMD | Revolution Medicines Inc | $2.25B | +5221.69% |
| INSM | Insmed Inc | $2.08B | +4801.68% |
| ASND | Ascendis Pharma A/S | $2.01B | +4635.23% |
| INVA | Innoviva Inc | $1.84B | +4236.69% |
| TLX | Telix Pharmaceuticals Ltd | $1.77B | +4081.62% |
| KYMR | Kymera Therapeutics Inc | $1.67B | +3841.01% |
| ACAD | Acadia Pharmaceuticals Inc | $1.61B | +3690.39% |
| LEGN | Legend Biotech Corp | $1.60B | +3670.36% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $1.53B | +3517.72% |
| TGTX | TG Therapeutics Inc | $1.53B | +3510.00% |
| GPCR | Structure Therapeutics Inc | $1.51B | +3461.10% |
| BEAM | Beam Therapeutics Inc | $1.48B | +3396.57% |
| PRAX | Praxis Precision Medicines Inc | $1.46B | +3347.94% |
| CRNX | Crinetics Pharmaceuticals Inc | $1.40B | +3208.91% |
| KRYS | Krystal Biotech Inc | $1.40B | +3198.62% |
| XENE | Xenon Pharmaceuticals Inc | $1.39B | +3174.64% |
| BBIO | BridgeBio Pharma Inc | $1.37B | +3137.26% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.34B | +3062.98% |
| NUVL | Nuvalent Inc - Class A | $1.33B | +3043.21% |
| ABCL | AbCellera Biologics Inc | $1.31B | +2986.45% |
| RARE | Ultragenyx Pharmaceutical Inc | $1.30B | +2960.21% |
| APGE | Apogee Therapeutics Inc | $1.29B | +2954.67% |
| CYTK | Cytokinetics Inc | $1.27B | +2907.03% |
| HRMY | Harmony Biosciences Holdings Inc | $1.27B | +2903.13% |
| DNLI | Denali Therapeutics Inc | $1.27B | +2889.43% |
| DNTH | Dianthus Therapeutics Inc | $1.25B | +2844.24% |
| MDGL | Madrigal Pharmaceuticals Inc | $1.23B | +2798.06% |
| AGIO | Agios Pharmaceuticals Inc | $1.18B | +2698.09% |
| CAI | Caris Life Sciences Inc - Class A | $1.16B | +2644.72% |
| CPRX | Catalyst Pharmaceuticals Inc | $1.15B | +2609.82% |
| CVAC | CureVac N.V. | $1.14B | +2588.59% |
| CGON | Cg Oncology Inc | $1.14B | +2580.67% |
| ZLAB | Zai Lab Ltd | $1.10B | +2487.34% |
| APLS | Apellis Pharmaceuticals Inc | $1.08B | +2456.16% |
| DYN | Dyne Therapeutics Inc | $1.08B | +2450.06% |
| IMCR | Immunocore Holdings plc | $1.07B | +2431.51% |
| NVAX | Novavax Inc | $1.04B | +2363.19% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $1.03B | +2339.37% |
| IDYA | Ideaya Biosciences Inc | $1.03B | +2332.94% |
| JANX | Janux Therapeutics Inc | $1.03B | +2327.92% |
| VIR | Vir Biotechnology Inc | $1.03B | +2321.69% |
| TERN | Terns Pharmaceuticals Inc | $1.03B | +2320.49% |
| AKRO | Akero Therapeutics Inc | $1.01B | +2274.44% |
| RCUS | Arcus Biosciences Inc | $997.00M | +2254.19% |
| IMVT | Immunovant Inc | $957.01M | +2159.77% |
| FOLD | Amicus Therapeutics Inc | $949.87M | +2142.90% |
| IOVA | Iovance Biotherapeutics Inc | $925.66M | +2085.75% |
| MRUS | Merus N.V | $904.20M | +2035.06% |
| COGT | Cogent Biosciences Inc | $903.01M | +2032.25% |
| MIRM | Mirum Pharmaceuticals Inc | $890.92M | +2003.70% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $849.19M | +1905.17% |
| CRMD | CorMedix Inc | $815.64M | +1825.94% |
| CORT | Corcept Therapeutics Inc | $814.88M | +1824.16% |
| VRDN | Viridian Therapeutics Inc | $789.02M | +1763.09% |
| MESO | Mesoblast Ltd | $784.68M | +1752.85% |
| BLTE | Belite Bio Inc | $780.56M | +1743.11% |
| QURE | uniQure N.V. | $778.71M | +1738.74% |
| SYRE | Spyre Therapeutics Inc | $763.95M | +1703.90% |
| NKTR | Nektar Therapeutics | $763.27M | +1702.29% |
| NTLA | Intellia Therapeutics Inc | $758.78M | +1691.69% |
| IRON | Disc Medicine Inc | $750.21M | +1671.46% |
| ZBIO | Zenas Biopharma Inc | $747.68M | +1665.48% |
| MNKD | Mannkind Corp | $744.40M | +1657.74% |
| XNCR | Xencor Inc | $736.85M | +1639.90% |
| GLUE | Monte Rosa Therapeutics Inc | $736.43M | +1638.91% |
| NAMS | NewAmsterdam Pharma Company NV | $732.64M | +1629.97% |
| OCUL | Ocular Therapeutix Inc | $732.53M | +1629.70% |
| AUPH | Aurinia Pharmaceuticals Inc | $724.00M | +1609.56% |
| AXSM | Axsome Therapeutics Inc | $713.61M | +1585.02% |
| RLAY | Relay Therapeutics Inc | $699.61M | +1551.98% |
| PTGX | Protagonist Therapeutics Inc | $697.46M | +1546.89% |
| ALMS | Alumis Inc | $671.59M | +1485.80% |
| ADMA | Adma Biologics Inc | $665.18M | +1470.68% |
| MLYS | Mineralys Therapeutics Inc | $652.86M | +1441.59% |
| KURA | Kura Oncology Inc | $652.55M | +1440.85% |
| BCYC | Bicycle Therapeutics Plc | $652.40M | +1440.49% |
| SMMT | Summit Therapeutics Inc | $647.86M | +1429.77% |
| ARVN | Arvinas Inc | $647.50M | +1428.93% |
| IBRX | ImmunityBio Inc | $646.64M | +1426.89% |
| CNTA | Centessa Pharmaceuticals plc | $641.76M | +1415.38% |
| NRIX | Nurix Therapeutics Inc | $636.13M | +1402.08% |
| VERA | Vera Therapeutics Inc - Class A | $621.74M | +1368.10% |
| IMNM | Immunome Inc | $619.79M | +1363.50% |
| NUVB | Nuvation Bio Inc - Class A | $610.24M | +1340.95% |
| SLNO | Soleno Therapeutics Inc | $608.39M | +1336.57% |
| VKTX | Viking Therapeutics Inc | $608.24M | +1336.23% |
| ACLX | Arcellx Inc | $603.99M | +1326.19% |
| THAR | Tharimmune Inc | $584.65M | +1280.53% |
| WVE | Wave Life Sciences Ltd | $583.54M | +1277.91% |
| TARS | Tarsus Pharmaceuticals Inc | $581.13M | +1272.22% |
| VRNA | Verona Pharma Plc | $572.87M | +1252.71% |
| SEPN | Septerna Inc | $569.69M | +1245.19% |
| TVTX | Travere Therapeutics Inc | $555.19M | +1210.95% |
| BCAX | Bicara Therapeutics Inc | $553.60M | +1207.20% |
| PRTC | PureTech Health plc American Depositary Shares | $553.24M | +1206.36% |
| ABVX | Abivax | $547.14M | +1191.95% |
| IMTX | Immatics N.V | $543.83M | +1184.13% |
| GLTO | Galecto Inc | $535.44M | +1164.33% |
| SRRK | Scholar Rock Holding Corp | $535.25M | +1163.88% |
| GERN | Geron Corp | $534.12M | +1161.20% |
| OLMA | Olema Pharmaceuticals Inc | $530.64M | +1153.00% |
| AUTL | Autolus Therapeutics plc | $527.07M | +1144.55% |
| CDTX | Cidara Therapeutics Inc | $518.65M | +1124.68% |
| EWTX | Edgewise Therapeutics Inc | $518.52M | +1124.37% |
| FDMT | 4D Molecular Therapeutics Inc | $512.90M | +1111.11% |
| CLDX | Celldex Therapeutics Inc | $511.25M | +1107.21% |
| DAWN | Day One Biopharmaceuticals Inc | $507.83M | +1099.12% |
| VOR | Vor Biopharma Inc | $506.75M | +1096.57% |
| RIGL | Rigel Pharmaceuticals | $504.61M | +1091.52% |
| ARDX | Ardelyx Inc | $504.51M | +1091.28% |
| ORKA | ARCA biopharma Inc | $504.48M | +1091.22% |
| RAPP | Rapport Therapeutics Inc | $497.60M | +1074.96% |
| PHAR | Pharming Group N.V. | $489.37M | +1055.53% |
| ZYME | Zymeworks BC Inc | $478.21M | +1029.20% |
| SNDX | Syndax Pharmaceuticals Inc | $472.67M | +1016.10% |
| TBPH | Theravance Biopharma Inc | $472.31M | +1015.26% |
| BHVN | Biohaven Ltd | $466.41M | +1001.31% |
| ELVN | Enliven Therapeutics Inc | $464.85M | +997.64% |
| RVNC | Revance Therapeutics Inc | $461.56M | +989.88% |
| ERAS | Erasca Inc | $461.23M | +989.10% |
| ARQT | Arcutis Biotherapeutics Inc | $460.00M | +986.19% |
| MBX | MBX Biosciences Inc | $452.70M | +968.95% |
| STOK | Stoke Therapeutics Inc | $443.28M | +946.70% |
| RYTM | Rhythm Pharmaceuticals Inc | $442.32M | +944.43% |
| ORIC | ORIC Pharmaceuticals Inc | $436.76M | +931.32% |
| SLRN | Acelyrin Inc | $436.50M | +930.71% |
| TNGX | Tango Therapeutics Inc | $435.79M | +929.02% |
| VNDA | Vanda Pharmaceuticals Inc | $433.52M | +923.67% |
| SLDB | Solid Biosciences Inc | $422.89M | +898.57% |
| MAZE | Maze Therapeutics Inc | $419.71M | +891.05% |
| MPLT | MapLight Therapeutics Inc | $418.79M | +888.87% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $417.65M | +886.18% |
| TYRA | Tyra Biosciences Inc | $412.04M | +872.94% |
| CELC | Celcuity Inc | $410.16M | +868.51% |
| CGEM | Cullinan Oncology Inc | $402.98M | +851.56% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $401.29M | +847.56% |
| MLTX | MoonLake Immunotherapeutics - Class A | $400.37M | +845.39% |
| ALLO | Allogene Therapeutics Inc | $395.96M | +834.97% |
| LBRX | LB Pharmaceuticals Inc | $393.48M | +829.12% |
| SANA | Sana Biotechnology Inc | $373.59M | +782.16% |
| NKTX | Nkarta Inc | $372.07M | +778.57% |
| CTMX | CytomX Therapeutics Inc | $359.36M | +748.54% |
| FBIO | Fortress Biotech Inc | $356.87M | +742.68% |
| PROK | ProKidney Corp - Class A | $351.61M | +730.24% |
| LYEL | Lyell Immunopharma Inc | $350.63M | +727.92% |
| PRTA | Prothena Corporation plc | $349.89M | +726.20% |
| AVBP | ArriVent BioPharma Inc | $349.30M | +724.78% |
| FULC | Fulcrum Therapeutics Inc | $346.77M | +718.82% |
| RGNX | Regenxbio Inc | $341.89M | +707.31% |
| ENGN | enGene Holdings Inc | $337.11M | +696.02% |
| TRDA | Entrada Therapeutics Inc | $335.52M | +692.25% |
| REPL | Replimune Group Inc | $333.59M | +687.70% |
| ANAB | AnaptysBio Inc | $329.68M | +678.47% |
| KALV | KalVista Pharmaceuticals Inc | $328.92M | +676.66% |
| CCCC | C4 Therapeutics Inc | $328.86M | +676.53% |
| IPSC | Century Therapeutics Inc | $326.55M | +671.08% |
| CAPR | Capricor Therapeutics Inc | $326.28M | +670.45% |
| CBUS | Cibus Global Ltd. Class A | $324.20M | +665.53% |
| EVMN | Evommune Inc | $322.45M | +661.40% |
| JBIO | Jade Biosciences Inc | $319.43M | +654.27% |
| UPB | Upstream Bio Inc | $318.05M | +651.01% |
| ENTA | Enanta Pharmaceuticals Inc | $314.70M | +643.10% |
| KROS | Keros Therapeutics Inc | $312.29M | +637.41% |
| DRUG | Bright Minds Biosciences Inc | $312.15M | +637.06% |
| MDXG | Mimedx Group Inc | $308.68M | +628.87% |
| KOD | Kodiak Sciences Inc | $306.01M | +622.56% |
| PHAT | Phathom Pharmaceuticals Inc | $305.12M | +620.47% |
| SION | Sionna Therapeutics Inc | $305.04M | +620.28% |
| TSHA | Taysha Gene Therapies Inc | $300.35M | +609.21% |
| PRME | Prime Medicine Inc | $294.73M | +595.94% |
| OABI | OmniAb Inc | $293.65M | +593.39% |
| RNA | Atrium Therapeutics Inc | $292.36M | +590.34% |
| ADCT | Adc Therapeutics SA | $291.50M | +588.30% |
| CLLS | Cellectis | $289.19M | +582.85% |
| RNAC | Cartesian Therapeutics Inc | $288.39M | +580.97% |
| EYPT | EyePoint Pharmaceuticals Inc | $288.22M | +580.56% |
| SPRY | ARS Pharmaceuticals Inc | $287.57M | +579.03% |
| OMER | Omeros Corporation | $286.17M | +575.73% |
| RCKT | Rocket Pharmaceuticals Inc | $285.41M | +573.92% |
| FATE | Fate Therapeutics Inc | $284.92M | +572.77% |
| ALT | Altimmune Inc | $279.93M | +560.99% |
| THRD | Third Harmonic Bio Inc | $279.84M | +560.77% |
| ZVRA | Zevra Therapeutics Inc | $278.58M | +557.80% |
| ABUS | Arbutus Biopharma Corp | $277.16M | +554.46% |
| ANRO | Alto Neuroscience Inc | $276.26M | +552.32% |
| GHRS | GH Research PLC | $275.27M | +549.98% |
| LENZ | LENZ Therapeutics Inc | $272.54M | +543.53% |
| SEER | Seer Inc - Class A | $272.13M | +542.58% |
| ATXS | Astria Therapeutics Inc | $271.87M | +541.95% |
| XOMA | XOMA Corp | $271.86M | +541.93% |
| XFOR | X4 Pharmaceuticals Inc | $270.28M | +538.21% |
| TRML | Tourmaline Bio Inc | $269.30M | +535.88% |
| ORMP | Oramed Pharmaceuticals Inc | $268.85M | +534.82% |
| LXRX | Lexicon Pharmaceuticals Inc | $268.82M | +534.76% |
| AVIR | Atea Pharmaceuticals Inc | $267.08M | +530.64% |
| DBVT | DBV Technologies | $266.40M | +529.04% |
| CHRS | Coherus Biosciences Inc | $266.02M | +528.15% |
| ATAI | ATAI Life Sciences N.V. | $264.88M | +525.45% |
| PVLA | Palvella Therapeutics Inc | $263.76M | +522.81% |
| NGNE | Neoleukin Therapeutics Inc | $263.14M | +521.35% |
| ANNX | Annexon Inc | $262.89M | +520.75% |
| TCRX | Tscan Therapeutics Inc | $262.23M | +519.19% |
| CTNM | Contineum Therapeutics Inc - Class A | $261.35M | +517.12% |
| PHVS | Pharvaris NV | $259.79M | +513.43% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $257.91M | +509.00% |
| KYTX | Kyverna Therapeutics Inc | $257.02M | +506.90% |
| URGN | UroGen Pharma Ltd | $253.69M | +499.03% |
| CRVS | Corvus Pharmaceuticals Inc | $253.19M | +497.86% |
| ZNTL | Zentalis Pharmaceuticals Inc | $253.07M | +497.56% |
| LXEO | Lexeo Therapeutics Inc | $250.36M | +491.16% |
| SABS | SAB Biotherapeutics Inc | $248.47M | +486.71% |
| TECX | AvroBio Inc | $246.58M | +482.24% |
| HRTX | Heron Therapeutics Inc | $246.22M | +481.38% |
| ARCT | Arcturus Therapeutics Holdings Inc | $245.41M | +479.48% |
| MGTX | MeiraGTx Holdings plc | $244.66M | +477.70% |
| OCS | Oculis Holding AG | $243.26M | +474.41% |
| STRO | Sutro Biopharma Inc | $241.99M | +471.40% |
| IVVD | Invivyd Inc | $241.74M | +470.82% |
| ALEC | Alector Inc | $239.92M | +466.51% |
| ASMB | Assembly Biosciences Inc | $235.51M | +456.10% |
| RLMD | Relmada Therapeutics Inc | $235.36M | +455.76% |
| DSGN | Design Therapeutics Inc | $230.44M | +444.14% |
| ZURA | Zura Bio Ltd - Class A | $228.64M | +439.88% |
| VSTM | Verastem Inc | $227.81M | +437.92% |
| OVID | Ovid Therapeutics Inc | $225.63M | +432.77% |
| FHTX | Foghorn Therapeutics Inc | $222.17M | +424.60% |
| SVRA | Savara Inc | $221.65M | +423.36% |
| VYGR | Voyager Therapeutics Inc | $219.32M | +417.89% |
| MGNX | Macrogenics Inc | $217.87M | +414.46% |
| IMRX | Immuneering Corp Class A | $214.81M | +407.23% |
| VTYX | Ventyx Biosciences Inc | $211.47M | +399.33% |
| LRMR | Larimar Therapeutics Inc | $208.51M | +392.35% |
| IMAB | I-Mab | $206.71M | +388.09% |
| SNSE | Sensei Biotherapeutics Inc | $205.38M | +384.96% |
| CMPX | Compass Therapeutics Inc | $205.17M | +384.46% |
| PLRX | Pliant Therapeutics Inc | $202.60M | +378.38% |
| CADL | Candel Therapeutics Inc | $201.92M | +376.79% |
| TIL | Instil Bio Inc | $200.43M | +373.27% |
| CBIO | N/A | $199.13M | +370.20% |
| ACRS | Aclaris Therapeutics Inc | $198.72M | +369.23% |
| ABEO | Abeona Therapeutics Inc | $198.49M | +368.70% |
| MGX | Metagenomi Inc | $196.95M | +365.06% |
| ABSI | Absci Corp | $195.59M | +361.85% |
| MIST | Milestone Pharmaceuticals Inc | $193.73M | +357.46% |
| PBYI | Puma Biotechnology Inc | $192.70M | +355.02% |
| TARA | Protara Therapeutics Inc | $191.92M | +353.18% |
| IMUX | Immunic Inc | $189.74M | +348.03% |
| BNTC | Benitec Biopharma Inc | $187.00M | +341.56% |
| AGEN | Agenus Inc | $186.46M | +340.27% |
| INBX | Inhibrx Biosciences Inc | $183.97M | +334.40% |
| KRRO | Korro Bio Inc | $183.62M | +333.58% |
| VXRT | Vaxart Inc | $180.06M | +325.16% |
| NBY | Stablecoin Development Corp | $179.74M | +324.42% |
| TRVI | Trevi Therapeutics Inc | $179.61M | +324.10% |
| IVA | Inventiva | $178.52M | +321.53% |
| ALXO | Alx Oncology Holdings Inc | $178.33M | +321.08% |
| NAUT | Nautilus Biotechnology Inc | $177.78M | +319.79% |
| HLVX | HilleVax Inc | $174.91M | +313.02% |
| IKT | Inhibikase Therapeutics Inc | $173.33M | +309.29% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $172.19M | +306.58% |
| AURA | Aura Biosciences Inc | $169.43M | +300.07% |
| ACET | Adicet Bio Inc | $169.38M | +299.96% |
| RAPT | RAPT Therapeutics Inc | $165.74M | +291.36% |
| XLO | Xilio Therapeutics Inc | $163.49M | +286.04% |
| GYRE | Gyre Therapeutics Inc | $162.01M | +282.56% |
| RNAZ | TransCode Therapeutics Inc | $157.16M | +271.11% |
| CGEN | Compugen Ltd | $156.57M | +269.70% |
| PEPG | PepGen Inc | $156.29M | +269.06% |
| NMRA | Neumora Therapeutics Inc | $153.88M | +263.35% |
| CLYM | Eliem Therapeutics Inc | $152.37M | +259.79% |
| EDIT | Editas Medicine Inc | $149.34M | +252.63% |
| CRBU | Caribou Biosciences Inc | $149.00M | +251.83% |
| CABA | Cabaletta Bio Inc | $148.15M | +249.81% |
| IMMP | Immutep Ltd | $147.20M | +247.58% |
| ELDN | Eledon Pharmaceuticals Inc | $146.67M | +246.32% |
| CMRX | Chimerix Inc | $146.01M | +244.77% |
| OPT | Opthea Ltd | $145.77M | +244.20% |
| PTHS | Channel Therapeutics Corporation | $145.38M | +243.28% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $144.48M | +241.16% |
| DTIL | Precision Biosciences Inc | $143.89M | +239.77% |
| BOLD | Boundless Bio Inc | $140.97M | +232.87% |
| XBIT | XBiotech Inc | $139.84M | +230.19% |
| PGEN | Precigen Inc | $138.63M | +227.34% |
| MNPR | Monopar Therapeutics Inc | $137.98M | +225.82% |
| ACIU | AC Immune SA | $137.42M | +224.49% |
| IMA | Ikena Oncology Inc | $136.68M | +222.74% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $135.37M | +219.65% |
| TNYA | Tenaya Therapeutics Inc | $135.07M | +218.94% |
| ABOS | Acumen Pharmaceuticals Inc | $133.63M | +215.53% |
| PALI | Palisade Bio Inc | $133.31M | +214.79% |
| AVXL | Anavex Life Sciences Corporation | $132.99M | +214.02% |
| BDTX | Black Diamond Therapeutics Inc | $132.92M | +213.87% |
| CTXR | Citius Pharmaceuticals Inc | $132.54M | +212.96% |
| KPTI | Karyopharm Therapeutics Inc | $131.42M | +210.31% |
| ARTV | Artiva Biotherapeutics Inc | $130.94M | +209.19% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $130.63M | +208.46% |
| CDXS | Codexis Inc | $129.37M | +205.48% |
| GOSS | Gossamer Bio Inc | $128.90M | +204.37% |
| WHWK | Whitehawk Therapeutics Inc | $127.23M | +200.43% |
| RPTX | Repare Therapeutics Inc | $126.75M | +199.28% |
| RZLT | Rezolute Inc | $125.46M | +196.24% |
| TENX | Tenax Therapeutics Inc | $123.18M | +190.86% |
| GBIO | Generation Bio Company | $121.90M | +187.83% |
| SRZN | Surrozen Inc | $120.71M | +185.03% |
| PRLD | Prelude Therapeutics Inc | $119.64M | +182.51% |
| MCRB | Seres Therapeutics Inc | $117.62M | +177.73% |
| YMAB | Y-Mabs Therapeutics Inc | $117.21M | +176.77% |
| SGMT | Sagimet Biosciences Inc - Class A | $116.48M | +175.05% |
| AVTX | Avalo Therapeutics Inc | $116.46M | +174.99% |
| SLN | Silence Therapeutics Plc | $115.12M | +171.84% |
| NAGE | Niagen Bioscience Inc | $114.33M | +169.96% |
| SLS | SELLAS Life Sciences Group Inc | $114.18M | +169.60% |
| HUMA | Humacyte Inc | $110.56M | +161.06% |
| EPIX | Essa Pharma Inc | $110.50M | +160.93% |
| KLRS | Kalaris Therapeutics Inc | $109.81M | +159.28% |
| FGEN | FibroGen Inc | $109.63M | +158.86% |
| LCTX | Lineage Cell Therapeutics Inc | $109.53M | +158.64% |
| SAVA | Cassava Sciences Inc. | $108.37M | +155.88% |
| ACRV | Acrivon Therapeutics Inc | $107.83M | +154.62% |
| CELU | Celularity Inc - Class A | $107.33M | +153.43% |
| DRTS | Alpha Tau Medical Ltd | $105.65M | +149.47% |
| CAMP | CAMP4 Therapeutics Corp | $105.46M | +149.01% |
| PLX | Protalix BioTherapeutics Inc | $102.34M | +141.64% |
| STTK | Shattuck Labs Inc | $102.12M | +141.14% |
| OBIO | Orchestra BioMed Holdings Inc | $100.66M | +137.68% |
| VTVT | vTv Therapeutics Inc - Class A | $99.49M | +134.93% |
| GUTS | Fractyl Health Inc | $99.39M | +134.68% |
| PRQR | ProQR Therapeutics N.V | $99.14M | +134.09% |
| AARD | Aardvark Therapeutics Inc | $98.59M | +132.80% |
| PMVP | PMV Pharmaceuticals Inc | $96.56M | +128.01% |
| IMMX | Immix Biopharma Inc | $95.82M | +126.25% |
| DWTX | Virios Therapeutics Inc | $95.21M | +124.81% |
| NERV | Minerva Neurosciences Inc | $94.03M | +122.02% |
| BRNS | Barinthus Biotherapeutics Plc. | $92.14M | +117.57% |
| ANTX | AN2 Therapeutics Inc | $87.49M | +106.59% |
| MOLN | Molecular Partners AG | $87.40M | +106.37% |
| EPRX | Eupraxia Pharmaceuticals Inc | $86.15M | +103.42% |
| IBIO | iBio Inc | $85.83M | +102.68% |
| FBRX | Forte Biosciences Inc | $82.78M | +95.46% |
| MDWD | MediWound Ltd | $79.98M | +88.86% |
| ATYR | Atyr Pharma Inc | $79.65M | +88.09% |
| ADAG | Adagene Inc | $78.26M | +84.80% |
| ADVM | Adverum Biotechnologies Inc | $72.40M | +70.96% |
| FENC | Fennec Pharmaceuticals Inc | $71.82M | +69.59% |
| ATHA | Athira Pharma Inc | $71.59M | +69.04% |
| HYPD | Eyenovia Inc | $70.07M | +65.45% |
| ARMP | Armata Pharmaceuticals Inc | $69.80M | +64.82% |
| ACOG | Alpha Cognition Inc | $69.25M | +63.51% |
| GRCE | Acasti Pharma Inc | $68.49M | +61.72% |
| KZR | Kezar Life Sciences Inc | $68.00M | +60.56% |
| NBTX | Nanobiotix | $67.76M | +60.00% |
| PMN | ProMIS Neurosciences Inc | $67.41M | +59.18% |
| IRD | Ocuphire Pharma Inc | $66.79M | +57.70% |
| ALDX | Aldeyra Therapeutics Inc | $66.48M | +56.98% |
| MURA | Mural Oncology plc | $65.76M | +55.27% |
| VTGN | VistaGen Therapeutics Inc | $65.06M | +53.62% |
| ALGS | Aligos Therapeutics Inc | $64.56M | +52.44% |
| UNCY | Unicycive Therapeutics Inc | $64.41M | +52.08% |
| PYXS | Pyxis Oncology Inc | $64.30M | +51.83% |
| QTTB | Q32 Bio Inc | $63.67M | +50.35% |
| EQ | Equillium Inc | $63.08M | +48.96% |
| IPHA | Innate Pharma | $62.69M | +48.03% |
| MRSN | Mersana Therapeutics Inc | $62.69M | +48.02% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $62.12M | +46.68% |
| HOOK | Hookipa Pharma Inc | $61.26M | +44.64% |
| CNTB | Connect Biopharma Holdings Ltd | $60.07M | +41.83% |
| SGMO | Sangamo Therapeutics Inc | $59.97M | +41.59% |
| KLTO | Klotho Neurosciences Inc Com | $59.74M | +41.06% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $59.74M | +41.06% |
| SPRO | Spero Therapeutics Inc | $59.02M | +39.36% |
| CNTX | Context Therapeutics Inc | $58.86M | +38.98% |
| HOWL | Werewolf Therapeutics Inc | $58.02M | +37.01% |
| LITS | Lite Strategy Inc | $57.79M | +36.46% |
| OCGN | Ocugen Inc | $56.91M | +34.37% |
| ATHE | Alterity Therapeutics Ltd | $56.86M | +34.27% |
| KTTA | Pasithea Therapeutics Corp | $56.35M | +33.07% |
| SPRB | Spruce Biosciences Inc | $56.17M | +32.62% |
| PMCB | PharmaCyte Biotech Inc | $55.87M | +31.93% |
| RLYB | Rallybio Corp | $54.47M | +28.62% |
| COYA | Coya Therapeutics Inc | $53.27M | +25.79% |
| DMAC | DiaMedica Therapeutics Inc | $53.08M | +25.34% |
| LVTX | LAVA Therapeutics NV | $51.91M | +22.59% |
| RANI | Rani Therapeutics Holdings Inc Class A | $51.88M | +22.50% |
| PHXM | PHAXIAM Therapeutics SA ADR | $51.31M | +21.15% |
| INO | Inovio Pharmaceuticals Inc | $49.78M | +17.54% |
| JAGX | Jaguar Health Inc | $49.47M | +16.82% |
| CRDF | Cardiff Oncology Inc | $49.17M | +16.11% |
| IFRX | InflaRx N.V. | $48.94M | +15.56% |
| BOLT | Bolt Biotherapeutics Inc | $48.03M | +13.40% |
| GRDX | Entero Therapeutics Inc | $47.97M | +13.26% |
| APRE | Aprea Therapeutics Inc | $47.61M | +12.43% |
| BMEA | Biomea Fusion Inc | $46.38M | +9.53% |
| ATNM | Actinium Pharmaceuticals Inc | $45.44M | +7.29% |
| AKTX | Akari Therapeutics Plc | $45.38M | +7.15% |
| ICCC | Immucell Corp | $44.11M | +4.15% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $43.47M | +2.65% |
| VERU | Veru Inc | $43.08M | +1.73% |
| MNOV | Medicinova Inc | $42.70M | +0.84% |
| ACHV | Achieve Life Sciences Inc | $41.79M | -1.32% |
| MREO | Mereo Biopharma Group Plc | $40.61M | -4.10% |
| IOBT | IO Biotech Inc | $39.96M | -5.65% |
| BLRX | Bioline Rx Ltd | $38.80M | -8.39% |
| VRCA | Verrica Pharmaceuticals Inc | $38.79M | -8.42% |
| TOVX | Theriva Biologics Inc | $38.25M | -9.69% |
| SNTI | Senti Biosciences Inc | $38.24M | -9.70% |
| NXTC | Nextcure Inc | $37.98M | -10.33% |
| ATOS | Atossa Therapeutics Inc | $37.94M | -10.41% |
| PASG | Passage Bio Inc | $36.46M | -13.90% |
| CGTX | Cognition Therapeutics Inc | $36.14M | -14.66% |
| LYRA | Lyra Therapeutics Inc | $36.11M | -14.74% |
| MAIA | MAIA Biotechnology Inc | $35.32M | -16.59% |
| ALLR | Allarity Therapeutics Inc | $34.92M | -17.54% |
| NEUP | Neuphoria Therapeutics Inc | $34.81M | -17.81% |
| APLT | Applied Therapeutics Inc | $34.37M | -18.83% |
| ITRM | Iterum Therapeutics Plc | $32.50M | -23.25% |
| GNLX | Genelux Corp | $32.37M | -23.56% |
| GNTA | Genenta Science SpA | $31.89M | -24.70% |
| CUE | Cue Biopharma Inc | $30.88M | -27.09% |
| CING | Cingulate Inc | $30.86M | -27.13% |
| SLGL | Sol-Gel Technologies Ltd | $29.92M | -29.36% |
| HURA | TuHURA Biosciences Inc | $29.70M | -29.86% |
| CRIS | Curis Inc | $29.69M | -29.90% |
| CSBR | Champions Oncology Inc | $28.45M | -32.83% |
| DARE | Dare Bioscience Inc | $27.83M | -34.29% |
| NCNA | NuCana plc | $27.55M | -34.94% |
| HCWB | HCW Biologics Inc | $27.34M | -35.44% |
| SER | AgeX Therapeutics Inc | $27.30M | -35.54% |
| BCTX | BriaCell Therapeutics Corp - New | $27.07M | -36.08% |
| QNCX | Quince Therapeutics Inc | $26.62M | -37.14% |
| INAB | IN8bio Inc | $26.27M | -37.98% |
| PLUR | Pluri Inc | $26.06M | -38.47% |
| VYNE | VYNE Therapeutics Inc | $25.87M | -38.91% |
| INMB | INmune Bio Inc | $25.82M | -39.04% |
| TVRD | Cara Therapeutics Inc | $25.82M | -39.04% |
| CASI | CASI Pharmaceuticals Inc | $25.65M | -39.43% |
| NVCT | Nuvectis Pharma Inc | $25.40M | -40.03% |
| LPCN | Lipocine Inc | $25.36M | -40.12% |
| PDSB | PDS Biotechnology Corporation | $24.66M | -41.76% |
| RNTX | Rein Therapeutics Inc | $24.16M | -42.96% |
| EVAX | Evaxion Biotech A/S | $23.64M | -44.17% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $23.56M | -44.37% |
| MBRX | Moleculin Biotech Inc | $23.36M | -44.83% |
| HYFT | MindWalk Holdings Corp | $23.17M | -45.30% |
| CVM | Cel-Sci Corp | $22.89M | -45.94% |
| ELTX | Elicio Therapeutics Inc | $22.69M | -46.43% |
| PYPD | Polypid Ltd | $22.31M | -47.33% |
| OTLK | Outlook Therapeutics Inc | $21.89M | -48.31% |
| PLRZ | Polyrizon Ltd | $21.44M | -49.38% |
| KPRX | Kiora Pharmaceuticals Inc | $21.23M | -49.88% |
| LGVN | Longeveron Inc - Class A | $21.21M | -49.92% |
| JSPR | Jasper Therapeutics Inc | $21.18M | -49.98% |
| MENS | Jyong Biotech Ltd | $20.78M | -50.94% |
| GNPX | Genprex Inc | $20.31M | -52.05% |
| LPTX | Leap Therapeutics Inc | $20.04M | -52.68% |
| ATRA | Atara Biotherapeutics Inc | $20.00M | -52.78% |
| PSTV | Plus Therapeutics Inc | $19.92M | -52.97% |
| APVO | Aptevo Therapeutics Inc | $19.90M | -53.01% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $19.79M | -53.28% |
| ABVC | ABVC BioPharma Inc | $19.73M | -53.41% |
| SKYE | Skye Bioscience Inc | $19.42M | -54.15% |
| GANX | Gain Therapeutics Inc | $18.74M | -55.75% |
| APM | Aptorum Group Ltd - Class A | $18.69M | -55.86% |
| TTRX | Turn Therapeutics Inc | $18.64M | -55.98% |
| GLMD | Galmed Pharmaceuticals Ltd | $18.63M | -56.02% |
| BYSI | BeyondSpring Inc | $18.41M | -56.54% |
| BDRX | Biodexa Pharmaceuticals Plc | $18.15M | -57.15% |
| EVGN | Evogene Ltd | $17.95M | -57.62% |
| BIVI | BioVie Inc - Class A | $17.51M | -58.64% |
| MRKR | Marker Therapeutics Inc | $17.43M | -58.83% |
| PHIO | Phio Pharmaceuticals Corp | $17.41M | -58.89% |
| IBO | Impact BioMedical Inc | $17.09M | -59.66% |
| MBIO | Mustang Bio Inc | $16.58M | -60.85% |
| ANVS | Annovis Bio Inc | $16.24M | -61.64% |
| GALT | Galectin Therapeutics Inc | $15.76M | -62.79% |
| QNRX | Quoin Pharmaceuticals Ltd | $15.69M | -62.94% |
| ONCT | Oncternal Therapeutics Inc | $15.60M | -63.16% |
| ANIX | Anixa Biosciences Inc | $15.23M | -64.03% |
| IMRN | Immuron Ltd | $15.12M | -64.29% |
| CRVO | CervoMed Inc | $15.11M | -64.31% |
| PPCB | Propanc Biopharma Inc | $15.11M | -64.32% |
| REVB | Revelation Biosciences Inc | $15.04M | -64.48% |
| CLRB | Cellectar Biosciences Inc | $14.98M | -64.63% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $14.98M | -64.64% |
| ELAB | PMGC Holdings Inc | $14.94M | -64.73% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $14.88M | -64.85% |
| ONCO | Onconetix Inc | $14.83M | -64.98% |
| SYBX | Synlogic Inc | $14.61M | -65.50% |
| MTVA | MetaVia Inc | $14.39M | -66.03% |
| LSTA | Lisata Therapeutics Inc | $14.06M | -66.80% |
| RNXT | RenovoRx Inc | $13.96M | -67.03% |
| CMMB | Chemomab Therapeutics Ltd | $13.81M | -67.39% |
| YDES | YD Bio Ltd | $13.78M | -67.46% |
| PTN | Palatin Technologies Inc | $13.23M | -68.77% |
| ENTX | Entera Bio Ltd | $13.13M | -69.00% |
| PBM | Psyence Biomedical Ltd | $12.81M | -69.75% |
| XCUR | Exicure Inc | $12.76M | -69.88% |
| ARTL | Artelo Biosciences Inc | $12.52M | -70.44% |
| EDSA | Edesa Biotech Inc | $12.38M | -70.76% |
| KALA | Kala Bio Inc | $12.32M | -70.91% |
| INTS | Intensity Therapeutics Inc | $12.29M | -70.98% |
| AZTR | Azitra Inc | $12.13M | -71.37% |
| NRXP | NRX Pharmaceuticals Inc | $11.90M | -71.89% |
| ADTX | Aditxt Inc | $11.80M | -72.14% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $11.64M | -72.51% |
| SCNI | Scinai Immunotherapeutics Ltd | $11.63M | -72.55% |
| NCEL | NLS Pharmaceutics Ltd | $11.45M | -72.98% |
| GRI | GRI Bio Inc | $11.34M | -73.23% |
| ICU | SeaStar Medical Holding Corp | $11.26M | -73.40% |
| CMND | Clearmind Medicine Inc | $11.14M | -73.70% |
| LIXT | Lixte Biotechnology Holdings Inc | $10.87M | -74.34% |
| CLGN | CollPlant Biotechnologies Ltd New | $10.79M | -74.53% |
| TPST | Tempest Therapeutics Inc | $10.75M | -74.62% |
| TRAW | Traws Pharma Inc | $10.62M | -74.93% |
| ERNA | Ernexa Therapeutics Inc | $10.54M | -75.11% |
| GLSI | Greenwich LifeSciences Inc | $10.51M | -75.19% |
| INKT | MiNK Therapeutics Inc | $10.38M | -75.50% |
| NNVC | NanoViricides Inc | $10.22M | -75.87% |
| HIND | ReShape Lifesciences Inc | $10.19M | -75.95% |
| LNAI | Lunai Bioworks Inc | $9.86M | -76.72% |
| CLDI | Calidi Biotherapeutics Inc | $9.59M | -77.35% |
| CDIO | Cardio Diagnostics Holdings Inc | $9.56M | -77.43% |
| ACXP | Acurx Pharmaceuticals Inc | $9.54M | -77.47% |
| CANF | Can-Fite Biopharma Ltd | $9.51M | -77.53% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $9.42M | -77.75% |
| IGC | IGC Pharma Inc | $9.19M | -78.31% |
| ACTU | Actuate Therapeutics Inc | $8.91M | -78.96% |
| NRXS | Neuraxis Inc | $8.75M | -79.35% |
| AEON | AEON Biopharma Inc - Class A | $8.63M | -79.62% |
| CALC | CalciMedica Inc | $8.61M | -79.67% |
| AIM | AIM ImmunoTech Inc. | $8.59M | -79.73% |
| BCAB | BioAtla Inc | $8.57M | -79.77% |
| CDT | CDT Equity Inc | $8.55M | -79.81% |
| CYCN | Cyclerion Therapeutics Inc | $8.51M | -79.92% |
| SLRX | Decoy Therapeutics Inc | $8.42M | -80.11% |
| CURX | Curanex Pharmaceuticals Inc | $8.41M | -80.14% |
| ONCY | Oncolytics Biotech Inc | $8.16M | -80.73% |
| IMNN | Imunon Inc | $8.02M | -81.07% |
| GDTC | CytoMed Therapeutics Ltd | $7.98M | -81.15% |
| XBIO | Xenetic Biosciences Inc | $7.91M | -81.32% |
| DYAI | Dyadic International Inc DE | $7.81M | -81.56% |
| BGMS | Bio Green Med Solution Inc | $7.56M | -82.14% |
| NTRB | Nutriband Inc | $7.55M | -82.18% |
| OGEN | Oragenics Inc | $7.49M | -82.31% |
| DRMA | Dermata Therapeutics Inc | $7.47M | -82.37% |
| COCP | Cocrystal Pharma Inc | $7.43M | -82.47% |
| TELO | Telomir Pharmaceuticals Inc | $7.34M | -82.67% |
| OSTX | OS Therapies Inc | $7.30M | -82.76% |
| LTRN | Lantern Pharma Inc | $7.22M | -82.94% |
| ASBP | Aspire Biopharma Holdings Inc | $7.12M | -83.19% |
| SILO | SILO Pharma Inc | $7.02M | -83.43% |
| VIVS | VivoSim Labs Inc | $6.96M | -83.57% |
| SNGX | Soligenix Inc | $6.92M | -83.65% |
| INDP | Indaptus Therapeutics Inc | $6.84M | -83.85% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $6.76M | -84.03% |
| GTBP | GT Biopharma Inc | $6.76M | -84.04% |
| APLM | Apollomics Inc - Class A | $6.71M | -84.15% |
| LEXX | Lexaria Bioscience Corp | $6.49M | -84.68% |
| CELZ | Creative Medical Technology Holdings Inc | $6.44M | -84.79% |
| ADXN | Addex Therapeutics Ltd | $6.37M | -84.97% |
| FBLG | FibroBiologics Inc | $5.94M | -85.98% |
| MTNB | Matinas Biopharma Holdings Inc | $5.87M | -86.13% |
| KAPA | Kairos Pharma Ltd | $5.74M | -86.44% |
| VRAX | Virax Biolabs Group Ltd - Class A | $5.72M | -86.51% |
| HOTH | Hoth Therapeutics Inc | $5.59M | -86.79% |
| ENVB | Enveric Biosciences Inc | $5.52M | -86.96% |
| ADIL | Adial Pharmaceuticals Inc | $5.23M | -87.66% |
| BBLG | Bone Biologics Corp | $4.98M | -88.24% |
| TVGN | Tevogen Bio Holdings Inc | $4.92M | -88.38% |
| CNSP | Cns Pharmaceuticals Inc | $4.65M | -89.01% |
| OKYO | OKYO Pharma Ltd - New | $4.64M | -89.03% |
| BRTX | BioRestorative Therapies Inc | $4.64M | -89.04% |
| SLXN | Silexion Therapeutics Corp | $4.60M | -89.13% |
| PCSA | Processa Pharmaceuticals Inc | $4.52M | -89.32% |
| PULM | Pulmatrix Inc | $4.50M | -89.38% |
| PTIX | Protagenic Therapeutics Inc | $4.43M | -89.54% |
| ALZN | Alzamend Neuro Inc | $4.04M | -90.46% |
| EXOZ | Invizyne Technologies Inc | $4.02M | -90.51% |
| JUNS | Jupiter Neurosciences Inc | $3.95M | -90.68% |
| ESLA | Estrella Immunopharma Inc | $3.66M | -91.36% |
| NTHI | NeOnc Technologies Holdings Inc | $3.33M | -92.14% |
| TTNP | Titan Pharmaceuticals Inc (de) | $3.05M | -92.80% |
| GOVX | Geovax Labs Inc | $2.98M | -92.96% |
| CVKD | Cadrenal Therapeutics Inc | $2.86M | -93.24% |
| LIMN | Liminatus Pharma Inc | $2.79M | -93.41% |
| ENSC | Ensysce Biosciences Inc | $2.17M | -94.88% |
| XRTX | XORTX Therapeutics Inc | $2.15M | -94.92% |
| TCRT | Alaunos Therapeutics Inc | $1.88M | -95.55% |
| BCDA | BioCardia Inc | $1.71M | -95.96% |
| ABP | Abpro Holdings, Inc Common Stock | $1.06M | -97.49% |
| NRSN | NeuroSense Therapeutics Ltd | $1.03M | -97.57% |
| BCLI | Brainstorm Cell Therapeutics Inc | $755000.00 | -98.22% |
| ZVSA | ZyVersa Therapeutics Inc | $742223.00 | -98.25% |