Performance analysis of Upstream Bio (UPB)
Annual Return
Since Oct 11, 2024, UPB has had an average annual return of -47.62%, underperforming the benchmark SPY, which returned +16.81% annual.
| 2026 | 2025 | 2024 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| -74.29% | +65.14% | -25.27% |
Monthly Return
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Annually Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | +14.47% | -75.29% | +17.19% | +2% | -8.94% | -17.24% | +0.89% | -74.29% | |||||
| 2025 | -34.50% | -26.35% | -22.83% | +51.29% | -0.33% | +18.97% | +39.43% | +11.88% | +9.81% | +37.43% | +10.64% | -5.07% | +65.14% |
| 2024 | +12.73% | -11.82% | -24.83% | -25.27% |
Drawdown analysis of Upstream Bio (UPB)
The maximum drawdown for the UPB was -81.84%, occurring on Jun 16, 2026. This drawdown has not yet recovered.
The current UPB drawdown is -78.59%.
Since Oct 11, 2024 UPB has experienced the following drawdowns:
- 50% or more: 2 times
- 40% or more: 2 times
- 30% or more: 2 times
- 20% or more: 2 times
- 10% or more: 4 times
| Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -81.84% | Jan 13, 2026 | 106 | Jun 16, 2026 | Ongoing | Ongoing | Ongoing |
| -77.84% | Nov 5, 2024 | 104 | Apr 8, 2025 | 160 | Nov 25, 2025 | 264 |
| -14.99% | Dec 22, 2025 | 9 | Jan 6, 2026 | 4 | Jan 12, 2026 | 13 |
| -13.70% | Dec 1, 2025 | 1 | Dec 2, 2025 | 10 | Dec 16, 2025 | 11 |
| -6.45% | Oct 21, 2024 | 5 | Oct 28, 2024 | 6 | Nov 5, 2024 | 11 |
| -3.38% | Dec 16, 2025 | 1 | Dec 17, 2025 | 1 | Dec 18, 2025 | 2 |
| -2.88% | Nov 25, 2025 | 1 | Nov 26, 2025 | 2 | Dec 1, 2025 | 3 |
| -1.71% | Dec 18, 2025 | 1 | Dec 19, 2025 | 1 | Dec 22, 2025 | 2 |
| -1.62% | Oct 14, 2024 | 1 | Oct 15, 2024 | 1 | Oct 16, 2024 | 2 |
| -0.13% | Oct 16, 2024 | 1 | Oct 17, 2024 | 1 | Oct 18, 2024 | 2 |