| REGN | Regeneron Pharmaceuticals Inc | $40.87B | +590489.60% |
| VRTX | Vertex Pharmaceuticals Inc | $26.48B | +382622.54% |
| BNTX | BioNTech SE | $21.10B | +304756.62% |
| RPRX | Royalty Pharma plc - Class A | $19.82B | +286249.93% |
| GMAB | Genmab | $12.38B | +178741.04% |
| JAZZ | Jazz Pharmaceuticals plc | $11.86B | +171281.50% |
| MRNA | Moderna Inc | $11.49B | +165911.56% |
| ARGX | Argen X SE | $8.68B | +125372.51% |
| BMRN | Biomarin Pharmaceutical Inc | $8.59B | +124047.63% |
| ONC | BeiGene Ltd | $8.55B | +123507.21% |
| SVA | Sinovac Biotech Ltd | $8.54B | +123335.33% |
| INCY | Incyte Corp | $7.34B | +105956.55% |
| ROIV | Roivant Sciences Ltd | $5.71B | +82395.48% |
| ALNY | Alnylam Pharmaceuticals Inc | $4.97B | +71667.79% |
| AAPG | Ascentage Pharma Group International | $3.97B | +57213.60% |
| IONS | Ionis Pharmaceuticals Inc | $3.45B | +49755.04% |
| GLPG | Galapagos NV | $3.41B | +49106.19% |
| PCVX | Vaxcyte Inc | $3.35B | +48285.95% |
| SRPT | Sarepta Therapeutics Inc | $3.18B | +45838.35% |
| PTCT | PTC Therapeutics Inc | $2.87B | +41361.04% |
| CRSP | CRISPR Therapeutics AG | $2.73B | +39290.46% |
| FTRE | Fortrea Holdings Inc | $2.68B | +38677.46% |
| HALO | Halozyme Therapeutics Inc | $2.67B | +38523.11% |
| NBP | NovaBridge Biosciences. | $2.61B | +37659.64% |
| EXEL | Exelixis Inc | $2.59B | +37379.67% |
| TECH | Bio-Techne Corp | $2.55B | +36758.40% |
| ENLV | Enlivex Ltd | $2.33B | +33527.14% |
| ARWR | Arrowhead Pharmaceuticals Inc | $2.27B | +32678.40% |
| RVMD | Revolution Medicines Inc | $2.25B | +32468.45% |
| INSM | Insmed Inc | $2.08B | +29898.02% |
| ASND | Ascendis Pharma A/S | $2.01B | +28879.31% |
| INVA | Innoviva Inc | $1.84B | +26440.27% |
| TLX | Telix Pharmaceuticals Ltd | $1.77B | +25491.25% |
| KYMR | Kymera Therapeutics Inc | $1.67B | +24018.73% |
| ACAD | Acadia Pharmaceuticals Inc | $1.61B | +23096.97% |
| LEGN | Legend Biotech Corp | $1.60B | +22974.42% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $1.53B | +22040.25% |
| TGTX | TG Therapeutics Inc | $1.53B | +21993.02% |
| GPCR | Structure Therapeutics Inc | $1.51B | +21693.70% |
| BEAM | Beam Therapeutics Inc | $1.48B | +21298.82% |
| PRAX | Praxis Precision Medicines Inc | $1.46B | +21001.18% |
| CRNX | Crinetics Pharmaceuticals Inc | $1.40B | +20150.33% |
| KRYS | Krystal Biotech Inc | $1.40B | +20087.38% |
| XENE | Xenon Pharmaceuticals Inc | $1.39B | +19940.61% |
| BBIO | BridgeBio Pharma Inc | $1.37B | +19711.86% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.34B | +19257.25% |
| NUVL | Nuvalent Inc - Class A | $1.33B | +19136.24% |
| ABCL | AbCellera Biologics Inc | $1.31B | +18788.90% |
| RARE | Ultragenyx Pharmaceutical Inc | $1.30B | +18628.32% |
| APGE | Apogee Therapeutics Inc | $1.29B | +18594.42% |
| CYTK | Cytokinetics Inc | $1.27B | +18302.86% |
| HRMY | Harmony Biosciences Holdings Inc | $1.27B | +18278.96% |
| DNLI | Denali Therapeutics Inc | $1.27B | +18195.13% |
| DNTH | Dianthus Therapeutics Inc | $1.25B | +17918.55% |
| MDGL | Madrigal Pharmaceuticals Inc | $1.23B | +17635.94% |
| AGIO | Agios Pharmaceuticals Inc | $1.18B | +17024.13% |
| CAI | Caris Life Sciences Inc - Class A | $1.16B | +16697.51% |
| CPRX | Catalyst Pharmaceuticals Inc | $1.15B | +16483.96% |
| CVAC | CureVac N.V. | $1.14B | +16354.03% |
| CGON | Cg Oncology Inc | $1.14B | +16305.52% |
| ZLAB | Zai Lab Ltd | $1.10B | +15734.35% |
| APLS | Apellis Pharmaceuticals Inc | $1.08B | +15543.53% |
| DYN | Dyne Therapeutics Inc | $1.08B | +15506.21% |
| IMCR | Immunocore Holdings plc | $1.07B | +15392.70% |
| NVAX | Novavax Inc | $1.04B | +14974.60% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $1.03B | +14828.83% |
| IDYA | Ideaya Biosciences Inc | $1.03B | +14789.42% |
| JANX | Janux Therapeutics Inc | $1.03B | +14758.74% |
| VIR | Vir Biotechnology Inc | $1.03B | +14720.59% |
| TERN | Terns Pharmaceuticals Inc | $1.03B | +14713.27% |
| AKRO | Akero Therapeutics Inc | $1.01B | +14431.46% |
| RCUS | Arcus Biosciences Inc | $997.00M | +14307.51% |
| IMVT | Immunovant Inc | $957.01M | +13729.68% |
| FOLD | Amicus Therapeutics Inc | $949.87M | +13626.45% |
| IOVA | Iovance Biotherapeutics Inc | $925.66M | +13276.66% |
| MRUS | Merus N.V | $904.20M | +12966.42% |
| COGT | Cogent Biosciences Inc | $903.01M | +12949.22% |
| MIRM | Mirum Pharmaceuticals Inc | $890.92M | +12774.51% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $849.19M | +12171.55% |
| CRMD | CorMedix Inc | $815.64M | +11686.66% |
| CORT | Corcept Therapeutics Inc | $814.88M | +11675.74% |
| VRDN | Viridian Therapeutics Inc | $789.02M | +11301.98% |
| MESO | Mesoblast Ltd | $782.31M | +11205.01% |
| BLTE | Belite Bio Inc | $780.56M | +11179.71% |
| QURE | uniQure N.V. | $778.71M | +11152.98% |
| SYRE | Spyre Therapeutics Inc | $763.95M | +10939.78% |
| NKTR | Nektar Therapeutics | $763.27M | +10929.93% |
| NTLA | Intellia Therapeutics Inc | $758.78M | +10865.01% |
| IRON | Disc Medicine Inc | $750.21M | +10741.23% |
| ZBIO | Zenas Biopharma Inc | $747.68M | +10704.65% |
| MNKD | Mannkind Corp | $744.40M | +10657.27% |
| XNCR | Xencor Inc | $736.85M | +10548.06% |
| GLUE | Monte Rosa Therapeutics Inc | $736.43M | +10542.02% |
| NAMS | NewAmsterdam Pharma Company NV | $732.64M | +10487.33% |
| OCUL | Ocular Therapeutix Inc | $732.53M | +10485.68% |
| AUPH | Aurinia Pharmaceuticals Inc | $724.00M | +10362.38% |
| AXSM | Axsome Therapeutics Inc | $713.61M | +10212.24% |
| RLAY | Relay Therapeutics Inc | $699.61M | +10010.01% |
| PTGX | Protagonist Therapeutics Inc | $697.46M | +9978.89% |
| ALMS | Alumis Inc | $671.59M | +9605.03% |
| ADMA | Adma Biologics Inc | $665.18M | +9512.49% |
| MLYS | Mineralys Therapeutics Inc | $652.86M | +9334.42% |
| KURA | Kura Oncology Inc | $652.55M | +9329.93% |
| BCYC | Bicycle Therapeutics Plc | $652.40M | +9327.69% |
| SMMT | Summit Therapeutics Inc | $647.86M | +9262.08% |
| ARVN | Arvinas Inc | $647.50M | +9256.94% |
| IBRX | ImmunityBio Inc | $646.64M | +9244.47% |
| CNTA | Centessa Pharmaceuticals plc | $641.76M | +9174.03% |
| VERA | Vera Therapeutics Inc - Class A | $621.74M | +8884.67% |
| IMNM | Immunome Inc | $619.79M | +8856.53% |
| NUVB | Nuvation Bio Inc - Class A | $610.24M | +8718.51% |
| SLNO | Soleno Therapeutics Inc | $608.39M | +8691.73% |
| VKTX | Viking Therapeutics Inc | $608.24M | +8689.62% |
| ACLX | Arcellx Inc | $603.99M | +8628.18% |
| THAR | Tharimmune Inc | $584.65M | +8348.77% |
| WVE | Wave Life Sciences Ltd | $583.54M | +8332.72% |
| TARS | Tarsus Pharmaceuticals Inc | $581.13M | +8297.90% |
| VRNA | Verona Pharma Plc | $572.87M | +8178.48% |
| SEPN | Septerna Inc | $569.69M | +8132.49% |
| TVTX | Travere Therapeutics Inc | $555.19M | +7922.95% |
| BCAX | Bicara Therapeutics Inc | $553.60M | +7899.99% |
| PRTC | PureTech Health plc American Depositary Shares | $553.24M | +7894.83% |
| ABVX | Abivax | $547.14M | +7806.68% |
| IMTX | Immatics N.V | $543.83M | +7758.82% |
| NRIX | Nurix Therapeutics Inc | $535.54M | +7639.02% |
| GLTO | Galecto Inc | $535.44M | +7637.60% |
| SRRK | Scholar Rock Holding Corp | $535.25M | +7634.88% |
| GERN | Geron Corp | $534.12M | +7618.50% |
| OLMA | Olema Pharmaceuticals Inc | $530.64M | +7568.28% |
| AUTL | Autolus Therapeutics plc | $527.07M | +7516.55% |
| CDTX | Cidara Therapeutics Inc | $518.65M | +7394.94% |
| EWTX | Edgewise Therapeutics Inc | $518.52M | +7393.09% |
| FDMT | 4D Molecular Therapeutics Inc | $512.90M | +7311.92% |
| CLDX | Celldex Therapeutics Inc | $511.25M | +7288.06% |
| DAWN | Day One Biopharmaceuticals Inc | $507.83M | +7238.54% |
| VOR | Vor Biopharma Inc | $506.75M | +7222.92% |
| RIGL | Rigel Pharmaceuticals | $504.61M | +7192.02% |
| ARDX | Ardelyx Inc | $504.51M | +7190.56% |
| ORKA | ARCA biopharma Inc | $504.48M | +7190.17% |
| RAPP | Rapport Therapeutics Inc | $497.60M | +7090.71% |
| PHAR | Pharming Group N.V. | $489.37M | +6971.75% |
| VCEL | Vericel Corp | $485.63M | +6917.73% |
| ZYME | Zymeworks BC Inc | $478.21M | +6810.62% |
| SNDX | Syndax Pharmaceuticals Inc | $472.67M | +6730.46% |
| TBPH | Theravance Biopharma Inc | $472.31M | +6725.33% |
| BHVN | Biohaven Ltd | $466.41M | +6639.97% |
| ELVN | Enliven Therapeutics Inc | $464.85M | +6617.51% |
| RVNC | Revance Therapeutics Inc | $461.56M | +6570.00% |
| ERAS | Erasca Inc | $461.23M | +6565.23% |
| ARQT | Arcutis Biotherapeutics Inc | $460.00M | +6547.44% |
| MBX | MBX Biosciences Inc | $452.70M | +6441.92% |
| STOK | Stoke Therapeutics Inc | $443.28M | +6305.74% |
| RYTM | Rhythm Pharmaceuticals Inc | $442.32M | +6291.85% |
| ORIC | ORIC Pharmaceuticals Inc | $436.76M | +6211.59% |
| SLRN | Acelyrin Inc | $436.50M | +6207.86% |
| TNGX | Tango Therapeutics Inc | $435.79M | +6197.57% |
| VNDA | Vanda Pharmaceuticals Inc | $433.52M | +6164.81% |
| SLDB | Solid Biosciences Inc | $422.89M | +6011.17% |
| MAZE | Maze Therapeutics Inc | $419.71M | +5965.17% |
| MPLT | MapLight Therapeutics Inc | $418.79M | +5951.85% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $417.65M | +5935.35% |
| TYRA | Tyra Biosciences Inc | $412.04M | +5854.34% |
| CELC | Celcuity Inc | $410.16M | +5827.23% |
| CGEM | Cullinan Oncology Inc | $402.98M | +5723.47% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $401.29M | +5699.03% |
| MLTX | MoonLake Immunotherapeutics - Class A | $400.37M | +5685.75% |
| ALLO | Allogene Therapeutics Inc | $395.96M | +5621.94% |
| LBRX | LB Pharmaceuticals Inc | $393.48M | +5586.16% |
| SANA | Sana Biotechnology Inc | $373.59M | +5298.74% |
| VALN | Valneva SE | $372.40M | +5281.52% |
| NKTX | Nkarta Inc | $372.07M | +5276.78% |
| CTMX | CytomX Therapeutics Inc | $359.36M | +5093.03% |
| FBIO | Fortress Biotech Inc | $356.87M | +5057.14% |
| PROK | ProKidney Corp - Class A | $351.61M | +4981.04% |
| LYEL | Lyell Immunopharma Inc | $350.63M | +4966.85% |
| PRTA | Prothena Corporation plc | $349.89M | +4956.27% |
| AVBP | ArriVent BioPharma Inc | $349.30M | +4947.62% |
| FULC | Fulcrum Therapeutics Inc | $346.77M | +4911.13% |
| RGNX | Regenxbio Inc | $341.89M | +4840.66% |
| TRDA | Entrada Therapeutics Inc | $335.52M | +4748.53% |
| REPL | Replimune Group Inc | $332.39M | +4703.29% |
| ANAB | AnaptysBio Inc | $329.68M | +4664.22% |
| KALV | KalVista Pharmaceuticals Inc | $328.92M | +4653.14% |
| CCCC | C4 Therapeutics Inc | $328.86M | +4652.33% |
| IPSC | Century Therapeutics Inc | $326.55M | +4618.97% |
| CAPR | Capricor Therapeutics Inc | $326.28M | +4615.08% |
| CBUS | Cibus Global Ltd. Class A | $324.20M | +4585.00% |
| EVMN | Evommune Inc | $322.45M | +4559.75% |
| JBIO | Jade Biosciences Inc | $319.43M | +4516.08% |
| UPB | Upstream Bio Inc | $318.05M | +4496.16% |
| ENTA | Enanta Pharmaceuticals Inc | $314.70M | +4447.75% |
| KROS | Keros Therapeutics Inc | $312.29M | +4412.90% |
| DRUG | Bright Minds Biosciences Inc | $312.15M | +4410.78% |
| MDXG | Mimedx Group Inc | $308.68M | +4360.64% |
| ENGN | enGene Holdings Inc | $307.52M | +4343.99% |
| KOD | Kodiak Sciences Inc | $306.01M | +4322.05% |
| PHAT | Phathom Pharmaceuticals Inc | $305.12M | +4309.25% |
| SION | Sionna Therapeutics Inc | $305.04M | +4308.08% |
| TSHA | Taysha Gene Therapies Inc | $300.35M | +4240.33% |
| PRME | Prime Medicine Inc | $294.73M | +4159.10% |
| OABI | OmniAb Inc | $293.65M | +4143.50% |
| RNA | Atrium Therapeutics Inc | $292.36M | +4124.86% |
| CLLS | Cellectis | $289.19M | +4079.00% |
| RNAC | Cartesian Therapeutics Inc | $288.39M | +4067.50% |
| EYPT | EyePoint Pharmaceuticals Inc | $288.22M | +4064.99% |
| SPRY | ARS Pharmaceuticals Inc | $287.57M | +4055.65% |
| OMER | Omeros Corporation | $286.17M | +4035.45% |
| RCKT | Rocket Pharmaceuticals Inc | $285.41M | +4024.38% |
| FATE | Fate Therapeutics Inc | $284.92M | +4017.28% |
| ALT | Altimmune Inc | $279.93M | +3945.22% |
| THRD | Third Harmonic Bio Inc | $279.84M | +3943.87% |
| ZVRA | Zevra Therapeutics Inc | $278.58M | +3925.71% |
| ABUS | Arbutus Biopharma Corp | $277.16M | +3905.26% |
| ANRO | Alto Neuroscience Inc | $276.26M | +3892.18% |
| GHRS | GH Research PLC | $275.27M | +3877.85% |
| LENZ | LENZ Therapeutics Inc | $272.54M | +3838.37% |
| SEER | Seer Inc - Class A | $272.13M | +3832.54% |
| ATXS | Astria Therapeutics Inc | $271.87M | +3828.70% |
| XOMA | XOMA Royalty Corp | $271.86M | +3828.58% |
| XFOR | X4 Pharmaceuticals Inc | $270.28M | +3805.79% |
| TRML | Tourmaline Bio Inc | $269.30M | +3791.55% |
| ORMP | Oramed Pharmaceuticals Inc | $268.85M | +3785.07% |
| LXRX | Lexicon Pharmaceuticals Inc | $268.82M | +3784.67% |
| AVIR | Atea Pharmaceuticals Inc | $267.08M | +3759.48% |
| DBVT | DBV Technologies | $266.40M | +3749.71% |
| CHRS | Coherus Biosciences Inc | $266.02M | +3744.25% |
| ATAI | ATAI Life Sciences N.V. | $264.88M | +3727.70% |
| PVLA | Palvella Therapeutics Inc | $263.76M | +3711.55% |
| NGNE | Neoleukin Therapeutics Inc | $263.14M | +3702.62% |
| ANNX | Annexon Inc | $262.89M | +3698.96% |
| TCRX | Tscan Therapeutics Inc | $262.23M | +3689.38% |
| CTNM | Contineum Therapeutics Inc - Class A | $261.35M | +3676.72% |
| PHVS | Pharvaris NV | $259.79M | +3654.16% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $257.91M | +3627.05% |
| KYTX | Kyverna Therapeutics Inc | $257.02M | +3614.22% |
| URGN | UroGen Pharma Ltd | $253.69M | +3566.04% |
| CRVS | Corvus Pharmaceuticals Inc | $253.19M | +3558.89% |
| ZNTL | Zentalis Pharmaceuticals Inc | $253.07M | +3557.02% |
| LXEO | Lexeo Therapeutics Inc | $250.36M | +3517.86% |
| SABS | SAB Biotherapeutics Inc | $248.47M | +3490.61% |
| TECX | AvroBio Inc | $246.58M | +3463.25% |
| HRTX | Heron Therapeutics Inc | $246.22M | +3458.03% |
| ARCT | Arcturus Therapeutics Holdings Inc | $245.41M | +3446.40% |
| MGTX | MeiraGTx Holdings plc | $244.66M | +3435.48% |
| OCS | Oculis Holding AG | $243.26M | +3415.38% |
| STRO | Sutro Biopharma Inc | $241.99M | +3396.94% |
| IVVD | Invivyd Inc | $241.74M | +3393.38% |
| ALEC | Alector Inc | $239.92M | +3366.99% |
| ASMB | Assembly Biosciences Inc | $235.51M | +3303.29% |
| RLMD | Relmada Therapeutics Inc | $235.36M | +3301.20% |
| DSGN | Design Therapeutics Inc | $230.44M | +3230.09% |
| ZURA | Zura Bio Ltd - Class A | $228.64M | +3204.06% |
| VSTM | Verastem Inc | $227.81M | +3192.02% |
| OVID | Ovid Therapeutics Inc | $225.63M | +3160.52% |
| FHTX | Foghorn Therapeutics Inc | $222.17M | +3110.51% |
| SVRA | Savara Inc | $221.65M | +3102.96% |
| VYGR | Voyager Therapeutics Inc | $219.32M | +3069.44% |
| MGNX | Macrogenics Inc | $217.87M | +3048.45% |
| IMRX | Immuneering Corp Class A | $214.81M | +3004.19% |
| VTYX | Ventyx Biosciences Inc | $211.47M | +2955.85% |
| LRMR | Larimar Therapeutics Inc | $208.51M | +2913.16% |
| IMAB | I-Mab | $206.71M | +2887.11% |
| SNSE | Sensei Biotherapeutics Inc | $205.38M | +2867.93% |
| CMPX | Compass Therapeutics Inc | $205.17M | +2864.88% |
| PLRX | Pliant Therapeutics Inc | $202.60M | +2827.69% |
| CADL | Candel Therapeutics Inc | $201.92M | +2817.92% |
| TIL | Instil Bio Inc | $200.43M | +2796.36% |
| CBIO | N/A | $199.13M | +2777.60% |
| ACRS | Aclaris Therapeutics Inc | $198.72M | +2771.68% |
| ABEO | Abeona Therapeutics Inc | $198.49M | +2768.41% |
| MGX | Metagenomi Inc | $196.95M | +2746.14% |
| ABSI | Absci Corp | $195.59M | +2726.49% |
| MIST | Milestone Pharmaceuticals Inc | $193.73M | +2699.62% |
| PBYI | Puma Biotechnology Inc | $192.70M | +2684.67% |
| TARA | Protara Therapeutics Inc | $191.92M | +2673.45% |
| IMUX | Immunic Inc | $189.74M | +2641.94% |
| BNTC | Benitec Biopharma Inc | $187.00M | +2602.31% |
| AGEN | Agenus Inc | $186.46M | +2594.45% |
| INBX | Inhibrx Biosciences Inc | $183.97M | +2558.48% |
| KRRO | Korro Bio Inc | $183.62M | +2553.50% |
| VXRT | Vaxart Inc | $180.06M | +2501.95% |
| NBY | Stablecoin Development Corp | $179.74M | +2497.44% |
| IVA | Inventiva | $178.52M | +2479.74% |
| ALXO | Alx Oncology Holdings Inc | $178.33M | +2476.99% |
| NAUT | Nautilus Biotechnology Inc | $177.78M | +2469.06% |
| HLVX | HilleVax Inc | $174.91M | +2427.66% |
| IKT | Inhibikase Therapeutics Inc | $173.33M | +2404.80% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $172.19M | +2388.26% |
| AURA | Aura Biosciences Inc | $169.43M | +2348.41% |
| ACET | Adicet Bio Inc | $169.38M | +2347.72% |
| RAPT | RAPT Therapeutics Inc | $165.74M | +2295.07% |
| XLO | Xilio Therapeutics Inc | $163.49M | +2262.53% |
| GYRE | Gyre Therapeutics Inc | $162.01M | +2241.26% |
| RNAZ | TransCode Therapeutics Inc | $157.16M | +2171.17% |
| CGEN | Compugen Ltd | $156.57M | +2162.57% |
| PEPG | PepGen Inc | $156.29M | +2158.60% |
| NMRA | Neumora Therapeutics Inc | $153.88M | +2123.66% |
| CLYM | Eliem Therapeutics Inc | $152.37M | +2101.91% |
| EDIT | Editas Medicine Inc | $149.34M | +2058.06% |
| CRBU | Caribou Biosciences Inc | $149.00M | +2053.15% |
| CABA | Cabaletta Bio Inc | $148.15M | +2040.84% |
| IMMP | Immutep Ltd | $147.20M | +2027.20% |
| ELDN | Eledon Pharmaceuticals Inc | $146.67M | +2019.47% |
| CMRX | Chimerix Inc | $146.01M | +2009.94% |
| OPT | Opthea Ltd | $145.77M | +2006.50% |
| PTHS | Channel Therapeutics Corporation | $145.38M | +2000.84% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $144.48M | +1987.86% |
| DTIL | Precision Biosciences Inc | $143.89M | +1979.35% |
| BOLD | Boundless Bio Inc | $140.97M | +1937.14% |
| XBIT | XBiotech Inc | $139.84M | +1920.75% |
| PGEN | Precigen Inc | $138.63M | +1903.28% |
| MNPR | Monopar Therapeutics Inc | $137.98M | +1893.98% |
| ACIU | AC Immune SA | $137.42M | +1885.85% |
| IMA | Ikena Oncology Inc | $136.68M | +1875.17% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $135.37M | +1856.22% |
| TNYA | Tenaya Therapeutics Inc | $135.07M | +1851.88% |
| ABOS | Acumen Pharmaceuticals Inc | $133.63M | +1831.05% |
| PALI | Palisade Bio Inc | $133.31M | +1826.52% |
| AVXL | Anavex Life Sciences Corporation | $132.99M | +1821.81% |
| BDTX | Black Diamond Therapeutics Inc | $132.92M | +1820.84% |
| CTXR | Citius Pharmaceuticals Inc | $132.54M | +1815.33% |
| KPTI | Karyopharm Therapeutics Inc | $131.42M | +1799.09% |
| ARTV | Artiva Biotherapeutics Inc | $130.94M | +1792.20% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $130.63M | +1787.76% |
| CDXS | Codexis Inc | $129.37M | +1769.51% |
| GOSS | Gossamer Bio Inc | $128.90M | +1762.70% |
| WHWK | Whitehawk Therapeutics Inc | $127.23M | +1738.60% |
| RPTX | Repare Therapeutics Inc | $126.75M | +1731.60% |
| RZLT | Rezolute Inc | $125.46M | +1712.99% |
| TENX | Tenax Therapeutics Inc | $123.18M | +1680.03% |
| GBIO | Generation Bio Company | $121.90M | +1661.50% |
| SRZN | Surrozen Inc | $120.71M | +1644.35% |
| PRLD | Prelude Therapeutics Inc | $119.64M | +1628.93% |
| MCRB | Seres Therapeutics Inc | $117.62M | +1599.68% |
| YMAB | Y-Mabs Therapeutics Inc | $117.21M | +1593.80% |
| SGMT | Sagimet Biosciences Inc - Class A | $116.48M | +1583.27% |
| AVTX | Avalo Therapeutics Inc | $116.46M | +1582.92% |
| SLN | Silence Therapeutics Plc | $115.12M | +1563.63% |
| NAGE | Niagen Bioscience Inc | $114.33M | +1552.15% |
| SLS | SELLAS Life Sciences Group Inc | $114.18M | +1549.96% |
| HUMA | Humacyte Inc | $110.56M | +1497.64% |
| EPIX | Essa Pharma Inc | $110.50M | +1496.85% |
| KLRS | Kalaris Therapeutics Inc | $109.81M | +1486.78% |
| FGEN | FibroGen Inc | $109.63M | +1484.23% |
| LCTX | Lineage Cell Therapeutics Inc | $109.53M | +1482.85% |
| SAVA | Cassava Sciences Inc. | $108.37M | +1466.00% |
| ACRV | Acrivon Therapeutics Inc | $107.83M | +1458.27% |
| CELU | Celularity Inc - Class A | $107.33M | +1451.00% |
| DRTS | Alpha Tau Medical Ltd | $105.65M | +1426.76% |
| CAMP | CAMP4 Therapeutics Corp | $105.46M | +1423.95% |
| PLX | Protalix BioTherapeutics Inc | $102.34M | +1378.84% |
| STTK | Shattuck Labs Inc | $102.12M | +1375.74% |
| OBIO | Orchestra BioMed Holdings Inc | $100.66M | +1354.60% |
| VTVT | vTv Therapeutics Inc - Class A | $99.49M | +1337.77% |
| GUTS | Fractyl Health Inc | $99.39M | +1336.20% |
| PRQR | ProQR Therapeutics N.V | $99.14M | +1332.62% |
| AARD | Aardvark Therapeutics Inc | $98.59M | +1324.71% |
| PMVP | PMV Pharmaceuticals Inc | $96.56M | +1295.40% |
| IMMX | Immix Biopharma Inc | $95.82M | +1284.63% |
| DWTX | Virios Therapeutics Inc | $95.21M | +1275.84% |
| NERV | Minerva Neurosciences Inc | $94.03M | +1258.77% |
| BRNS | Barinthus Biotherapeutics Plc. | $92.14M | +1231.55% |
| ANTX | AN2 Therapeutics Inc | $87.49M | +1164.32% |
| MOLN | Molecular Partners AG | $87.40M | +1162.95% |
| EPRX | Eupraxia Pharmaceuticals Inc | $86.15M | +1144.94% |
| IBIO | iBio Inc | $85.83M | +1140.38% |
| FBRX | Forte Biosciences Inc | $82.78M | +1096.23% |
| MDWD | MediWound Ltd | $79.98M | +1055.81% |
| ATYR | Atyr Pharma Inc | $79.65M | +1051.07% |
| ADAG | Adagene Inc | $78.26M | +1030.97% |
| ADVM | Adverum Biotechnologies Inc | $72.40M | +946.26% |
| FENC | Fennec Pharmaceuticals Inc | $71.82M | +937.89% |
| ATHA | Athira Pharma Inc | $71.59M | +934.54% |
| HYPD | Eyenovia Inc | $70.07M | +912.51% |
| ARMP | Armata Pharmaceuticals Inc | $69.80M | +908.67% |
| ACOG | Alpha Cognition Inc | $69.25M | +900.70% |
| KZR | Kezar Life Sciences Inc | $68.00M | +882.64% |
| NBTX | Nanobiotix | $67.76M | +879.19% |
| PMN | ProMIS Neurosciences Inc | $67.41M | +874.16% |
| IRD | Ocuphire Pharma Inc | $66.79M | +865.13% |
| GRCE | Acasti Pharma Inc | $66.65M | +863.21% |
| ALDX | Aldeyra Therapeutics Inc | $66.48M | +860.74% |
| MURA | Mural Oncology plc | $65.76M | +850.26% |
| ALGS | Aligos Therapeutics Inc | $64.56M | +832.92% |
| UNCY | Unicycive Therapeutics Inc | $64.41M | +830.72% |
| PYXS | Pyxis Oncology Inc | $64.30M | +829.19% |
| QTTB | Q32 Bio Inc | $63.67M | +820.16% |
| EQ | Equillium Inc | $63.08M | +811.60% |
| IPHA | Innate Pharma | $62.69M | +805.96% |
| MRSN | Mersana Therapeutics Inc | $62.69M | +805.87% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $62.12M | +797.64% |
| HOOK | Hookipa Pharma Inc | $61.26M | +785.20% |
| CNTB | Connect Biopharma Holdings Ltd | $60.07M | +768.01% |
| SGMO | Sangamo Therapeutics Inc | $59.97M | +766.55% |
| KLTO | Klotho Neurosciences Inc Com | $59.74M | +763.25% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $59.74M | +763.25% |
| SPRO | Spero Therapeutics Inc | $59.02M | +752.90% |
| CNTX | Context Therapeutics Inc | $58.86M | +750.56% |
| HOWL | Werewolf Therapeutics Inc | $58.02M | +738.47% |
| LITS | Lite Strategy Inc | $57.79M | +735.10% |
| OCGN | Ocugen Inc | $56.91M | +722.33% |
| ATHE | Alterity Therapeutics Ltd | $56.86M | +721.71% |
| KTTA | Pasithea Therapeutics Corp | $56.35M | +714.38% |
| SPRB | Spruce Biosciences Inc | $56.17M | +711.65% |
| PMCB | PharmaCyte Biotech Inc | $55.87M | +707.42% |
| RLYB | Rallybio Corp | $54.47M | +687.17% |
| COYA | Coya Therapeutics Inc | $53.27M | +669.81% |
| DMAC | DiaMedica Therapeutics Inc | $53.08M | +667.05% |
| LVTX | LAVA Therapeutics NV | $51.91M | +650.22% |
| RANI | Rani Therapeutics Holdings Inc Class A | $51.88M | +649.70% |
| PHXM | PHAXIAM Therapeutics SA ADR | $51.31M | +641.43% |
| INO | Inovio Pharmaceuticals Inc | $49.78M | +619.32% |
| JAGX | Jaguar Health Inc | $49.47M | +614.91% |
| CRDF | Cardiff Oncology Inc | $49.17M | +610.58% |
| IFRX | InflaRx N.V. | $48.94M | +607.24% |
| VTGN | VistaGen Therapeutics Inc | $48.56M | +601.79% |
| BOLT | Bolt Biotherapeutics Inc | $48.03M | +594.03% |
| GRDX | Entero Therapeutics Inc | $47.97M | +593.15% |
| APRE | Aprea Therapeutics Inc | $47.61M | +588.04% |
| BMEA | Biomea Fusion Inc | $46.38M | +570.30% |
| ATNM | Actinium Pharmaceuticals Inc | $45.44M | +556.62% |
| AKTX | Akari Therapeutics Plc | $45.38M | +555.72% |
| ICCC | Immucell Corp | $44.11M | +537.40% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $43.47M | +528.18% |
| VERU | Veru Inc | $43.08M | +522.58% |
| MNOV | Medicinova Inc | $42.70M | +517.12% |
| VANI | Vivani Medical Inc | $42.35M | +512.04% |
| ACHV | Achieve Life Sciences Inc | $41.79M | +503.90% |
| MREO | Mereo Biopharma Group Plc | $40.61M | +486.91% |
| IOBT | IO Biotech Inc | $39.96M | +477.40% |
| BLRX | Bioline Rx Ltd | $38.80M | +460.65% |
| VRCA | Verrica Pharmaceuticals Inc | $38.79M | +460.49% |
| TOVX | Theriva Biologics Inc | $38.25M | +452.72% |
| SNTI | Senti Biosciences Inc | $38.24M | +452.62% |
| NXTC | Nextcure Inc | $37.98M | +448.80% |
| ATOS | Atossa Therapeutics Inc | $37.94M | +448.31% |
| PASG | Passage Bio Inc | $36.46M | +426.91% |
| CGTX | Cognition Therapeutics Inc | $36.14M | +422.25% |
| LYRA | Lyra Therapeutics Inc | $36.11M | +421.79% |
| MAIA | MAIA Biotechnology Inc | $35.32M | +410.44% |
| ALLR | Allarity Therapeutics Inc | $34.92M | +404.67% |
| NEUP | Neuphoria Therapeutics Inc | $34.81M | +403.02% |
| APLT | Applied Therapeutics Inc | $34.37M | +396.73% |
| ITRM | Iterum Therapeutics Plc | $32.50M | +369.70% |
| GNLX | Genelux Corp | $32.37M | +367.80% |
| GNTA | Genenta Science SpA | $31.89M | +360.83% |
| CUE | Cue Biopharma Inc | $30.88M | +346.20% |
| CING | Cingulate Inc | $30.86M | +345.98% |
| SLGL | Sol-Gel Technologies Ltd | $29.92M | +332.33% |
| HURA | TuHURA Biosciences Inc | $29.70M | +329.26% |
| CRIS | Curis Inc | $29.69M | +328.99% |
| CSBR | Champions Oncology Inc | $28.45M | +311.08% |
| DARE | Dare Bioscience Inc | $27.83M | +302.14% |
| NCNA | NuCana plc | $27.55M | +298.18% |
| HCWB | HCW Biologics Inc | $27.34M | +295.12% |
| SER | AgeX Therapeutics Inc | $27.30M | +294.49% |
| BCTX | BriaCell Therapeutics Corp - New | $27.07M | +291.20% |
| QNCX | Quince Therapeutics Inc | $26.62M | +284.73% |
| INAB | IN8bio Inc | $26.27M | +279.55% |
| PLUR | Pluri Inc | $26.06M | +276.55% |
| VYNE | VYNE Therapeutics Inc | $25.87M | +273.89% |
| INMB | INmune Bio Inc | $25.82M | +273.09% |
| TVRD | Cara Therapeutics Inc | $25.82M | +273.08% |
| CASI | CASI Pharmaceuticals Inc | $25.65M | +270.66% |
| NVCT | Nuvectis Pharma Inc | $25.40M | +267.02% |
| LPCN | Lipocine Inc | $25.36M | +266.45% |
| PDSB | PDS Biotechnology Corporation | $24.66M | +256.40% |
| RNTX | Rein Therapeutics Inc | $24.16M | +249.10% |
| EVAX | Evaxion Biotech A/S | $23.64M | +241.65% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $23.56M | +240.46% |
| MBRX | Moleculin Biotech Inc | $23.36M | +237.62% |
| HYFT | MindWalk Holdings Corp | $23.17M | +234.78% |
| CVM | Cel-Sci Corp | $22.89M | +230.85% |
| ELTX | Elicio Therapeutics Inc | $22.69M | +227.88% |
| PYPD | Polypid Ltd | $22.31M | +222.36% |
| OTLK | Outlook Therapeutics Inc | $21.89M | +216.36% |
| PLRZ | Polyrizon Ltd | $21.44M | +209.78% |
| KPRX | Kiora Pharmaceuticals Inc | $21.23M | +206.75% |
| LGVN | Longeveron Inc - Class A | $21.21M | +206.50% |
| JSPR | Jasper Therapeutics Inc | $21.18M | +206.13% |
| MENS | Jyong Biotech Ltd | $20.78M | +200.26% |
| GNPX | Genprex Inc | $20.31M | +193.44% |
| LPTX | Leap Therapeutics Inc | $20.04M | +189.62% |
| ATRA | Atara Biotherapeutics Inc | $20.00M | +188.97% |
| PSTV | Plus Therapeutics Inc | $19.92M | +187.80% |
| APVO | Aptevo Therapeutics Inc | $19.90M | +187.60% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $19.79M | +185.93% |
| ABVC | ABVC BioPharma Inc | $19.73M | +185.15% |
| SKYE | Skye Bioscience Inc | $19.42M | +180.59% |
| GANX | Gain Therapeutics Inc | $18.74M | +170.79% |
| APM | Aptorum Group Limited Class A Ordinary Shares | $18.69M | +170.11% |
| TTRX | Turn Therapeutics Inc | $18.64M | +169.42% |
| GLMD | Galmed Pharmaceuticals Ltd | $18.63M | +169.18% |
| BYSI | BeyondSpring Inc | $18.41M | +165.98% |
| BDRX | Biodexa Pharmaceuticals Plc | $18.15M | +162.24% |
| EVGN | Evogene Ltd | $17.95M | +159.36% |
| BIVI | BioVie Inc - Class A | $17.51M | +153.10% |
| MRKR | Marker Therapeutics Inc | $17.43M | +151.94% |
| PHIO | Phio Pharmaceuticals Corp | $17.41M | +151.62% |
| IBO | Impact BioMedical Inc | $17.09M | +146.91% |
| MBIO | Mustang Bio Inc | $16.58M | +139.62% |
| ANVS | Annovis Bio Inc | $16.24M | +134.74% |
| GALT | Galectin Therapeutics Inc | $15.76M | +127.73% |
| QNRX | Quoin Pharmaceuticals Ltd | $15.69M | +126.78% |
| ONCT | Oncternal Therapeutics Inc | $15.60M | +125.45% |
| IMRN | Immuron Ltd | $15.12M | +118.53% |
| CRVO | CervoMed Inc | $15.11M | +118.39% |
| PPCB | Propanc Biopharma Inc | $15.11M | +118.37% |
| REVB | Revelation Biosciences Inc | $15.04M | +117.40% |
| CLRB | Cellectar Biosciences Inc | $14.98M | +116.45% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $14.98M | +116.40% |
| ELAB | PMGC Holdings Inc | $14.94M | +115.87% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $14.88M | +115.09% |
| ANIX | Anixa Biosciences Inc | $14.87M | +114.81% |
| ONCO | Onconetix Inc | $14.83M | +114.34% |
| SYBX | Synlogic Inc | $14.61M | +111.14% |
| CMND | Clearmind Medicine Inc | $14.52M | +109.88% |
| MTVA | MetaVia Inc | $14.39M | +107.92% |
| LSTA | Lisata Therapeutics Inc | $14.06M | +103.16% |
| RNXT | RenovoRx Inc | $13.96M | +101.79% |
| ADTX | Aditxt Inc | $13.91M | +100.97% |
| CMMB | Chemomab Therapeutics Ltd | $13.81M | +99.60% |
| YDES | YD Bio Ltd | $13.78M | +99.12% |
| PTN | Palatin Technologies Inc | $13.23M | +91.12% |
| ENTX | Entera Bio Ltd | $13.13M | +89.73% |
| PBM | Psyence Biomedical Ltd | $12.81M | +85.12% |
| XCUR | Exicure Inc | $12.76M | +84.32% |
| ARTL | Artelo Biosciences Inc | $12.52M | +80.90% |
| EDSA | Edesa Biotech Inc | $12.38M | +78.97% |
| KALA | Kala Bio Inc | $12.32M | +78.01% |
| INTS | Intensity Therapeutics Inc | $12.29M | +77.62% |
| AZTR | Azitra Inc | $12.13M | +75.24% |
| NRXP | NRX Pharmaceuticals Inc | $11.90M | +72.01% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $11.64M | +68.22% |
| SCNI | Scinai Immunotherapeutics Ltd | $11.63M | +68.01% |
| NCEL | NLS Pharmaceutics Ltd | $11.45M | +65.39% |
| GRI | GRI Bio Inc | $11.34M | +63.86% |
| ICU | SeaStar Medical Holding Corp | $11.26M | +62.76% |
| TPST | Tempest Therapeutics Inc | $10.75M | +55.32% |
| ERNA | Ernexa Therapeutics Inc | $10.54M | +52.36% |
| GLSI | Greenwich LifeSciences Inc | $10.51M | +51.81% |
| INKT | MiNK Therapeutics Inc | $10.38M | +49.96% |
| NNVC | NanoViricides Inc | $10.22M | +47.67% |
| HIND | ReShape Lifesciences Inc | $10.19M | +47.19% |
| LNAI | Lunai Bioworks Inc | $9.86M | +42.49% |
| CLDI | Calidi Biotherapeutics Inc | $9.59M | +38.60% |
| CDIO | Cardio Diagnostics Holdings Inc | $9.56M | +38.14% |
| ACXP | Acurx Pharmaceuticals Inc | $9.54M | +37.86% |
| CANF | Can-Fite Biopharma Ltd | $9.51M | +37.49% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $9.42M | +36.16% |
| IGC | IGC Pharma Inc | $9.19M | +32.73% |
| CLGN | CollPlant Biotechnologies Ltd New | $9.18M | +32.70% |
| ACTU | Actuate Therapeutics Inc | $8.91M | +28.78% |
| NRXS | Neuraxis Inc | $8.75M | +26.38% |
| AEON | AEON Biopharma Inc - Class A | $8.63M | +24.71% |
| CALC | CalciMedica Inc | $8.61M | +24.41% |
| AIM | AIM ImmunoTech Inc. | $8.59M | +24.06% |
| BCAB | BioAtla Inc | $8.57M | +23.79% |
| CDT | CDT Equity Inc | $8.55M | +23.58% |
| CYCN | Cyclerion Therapeutics Inc | $8.51M | +22.90% |
| SLRX | Decoy Therapeutics Inc | $8.42M | +21.72% |
| CURX | Curanex Pharmaceuticals Inc | $8.41M | +21.55% |
| ONCY | Oncolytics Biotech Inc | $8.16M | +17.93% |
| TRAW | Traws Pharma Inc | $8.16M | +17.86% |
| IMNN | Imunon Inc | $8.02M | +15.88% |
| GDTC | CytoMed Therapeutics Ltd | $7.98M | +15.39% |
| XBIO | Xenetic Biosciences Inc | $7.91M | +14.29% |
| DYAI | Dyadic International Inc DE | $7.81M | +12.86% |
| BGMS | Bio Green Med Solution Inc | $7.56M | +9.31% |
| OGEN | Oragenics Inc | $7.49M | +8.23% |
| DRMA | Dermata Therapeutics Inc | $7.47M | +7.89% |
| COCP | Cocrystal Pharma Inc | $7.43M | +7.31% |
| VIVS | VivoSim Labs Inc | $7.39M | +6.73% |
| TELO | Telomir Pharmaceuticals Inc | $7.34M | +6.09% |
| OSTX | OS Therapies Inc | $7.30M | +5.48% |
| LTRN | Lantern Pharma Inc | $7.22M | +4.38% |
| ASBP | Aspire Biopharma Holdings Inc | $7.12M | +2.85% |
| SILO | SILO Pharma Inc | $7.02M | +1.42% |
| NTRB | Nutriband Inc | $6.89M | -0.40% |
| INDP | Indaptus Therapeutics Inc | $6.84M | -1.16% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $6.76M | -2.26% |
| GTBP | GT Biopharma Inc | $6.76M | -2.33% |
| APLM | Apollomics Inc - Class A | $6.71M | -2.98% |
| CELZ | Creative Medical Technology Holdings Inc | $6.44M | -6.93% |
| FBLG | FibroBiologics Inc | $5.94M | -14.19% |
| MTNB | Matinas Biopharma Holdings Inc | $5.87M | -15.12% |
| KAPA | Kairos Pharma Ltd | $5.74M | -16.99% |
| VRAX | Virax Biolabs Group Ltd - Class A | $5.72M | -17.41% |
| HOTH | Hoth Therapeutics Inc | $5.59M | -19.16% |
| ENVB | Enveric Biosciences Inc | $5.52M | -20.21% |
| ADIL | Adial Pharmaceuticals Inc | $5.23M | -24.46% |
| BBLG | Bone Biologics Corp | $4.98M | -28.04% |
| TVGN | Tevogen Bio Holdings Inc | $4.92M | -28.89% |
| LEXX | Lexaria Bioscience Corp | $4.78M | -30.91% |
| ADXN | Addex Therapeutics Ltd | $4.76M | -31.23% |
| CNSP | Cns Pharmaceuticals Inc | $4.65M | -32.76% |
| OKYO | OKYO Pharma Ltd - New | $4.64M | -32.89% |
| BRTX | BioRestorative Therapies Inc | $4.64M | -32.94% |
| SLXN | Silexion Therapeutics Corp | $4.60M | -33.50% |
| PCSA | Processa Pharmaceuticals Inc | $4.52M | -34.67% |
| PULM | Pulmatrix Inc | $4.50M | -35.03% |
| PTIX | Protagenic Therapeutics Inc | $4.43M | -35.97% |
| ALZN | Alzamend Neuro Inc | $4.04M | -41.59% |
| EXOZ | Invizyne Technologies Inc | $4.02M | -41.92% |
| JUNS | Jupiter Neurosciences Inc | $3.95M | -42.94% |
| ESLA | Estrella Immunopharma Inc | $3.66M | -47.15% |
| NTHI | NeOnc Technologies Holdings Inc | $3.33M | -51.88% |
| TTNP | Titan Pharmaceuticals Inc (de) | $3.05M | -55.91% |
| GOVX | Geovax Labs Inc | $2.98M | -56.90% |
| CVKD | Cadrenal Therapeutics Inc | $2.86M | -58.64% |
| LIMN | Liminatus Pharma Inc | $2.79M | -59.68% |
| ENSC | Ensysce Biosciences Inc | $2.17M | -68.67% |
| XRTX | XORTX Therapeutics Inc | $2.15M | -68.90% |
| TCRT | Alaunos Therapeutics Inc | $1.88M | -72.79% |
| BCDA | BioCardia Inc | $1.71M | -75.26% |
| ABP | Abpro Holdings, Inc Common Stock | $1.06M | -84.64% |
| NRSN | NeuroSense Therapeutics Ltd | $1.03M | -85.14% |
| BCLI | Brainstorm Cell Therapeutics Inc | $755000.00 | -89.09% |
| ZVSA | ZyVersa Therapeutics Inc | $742223.00 | -89.27% |