| REGN | Regeneron Pharmaceuticals Inc | $40.87B | +356832.75% |
| VRTX | Vertex Pharmaceuticals Inc | $26.48B | +231204.80% |
| BNTX | BioNTech SE | $21.10B | +184145.22% |
| RPRX | Royalty Pharma plc - Class A | $19.82B | +172960.39% |
| GMAB | Genmab | $12.38B | +107985.59% |
| JAZZ | Jazz Pharmaceuticals plc | $11.86B | +103477.29% |
| MRNA | Moderna Inc | $11.49B | +100231.88% |
| ARGX | Argen X SE | $8.68B | +75731.42% |
| BMRN | Biomarin Pharmaceutical Inc | $8.59B | +74930.71% |
| ONC | BeiGene Ltd | $8.55B | +74604.10% |
| SVA | Sinovac Biotech Ltd | $8.54B | +74500.22% |
| INCY | Incyte Corp | $7.34B | +63997.06% |
| ROIV | Roivant Sciences Ltd | $5.71B | +49757.53% |
| ALNY | Alnylam Pharmaceuticals Inc | $4.97B | +43274.07% |
| AAPG | Ascentage Pharma Group International | $3.97B | +34538.44% |
| IONS | Ionis Pharmaceuticals Inc | $3.45B | +30030.73% |
| GLPG | Galapagos NV | $3.41B | +29638.59% |
| PCVX | Vaxcyte Inc | $3.35B | +29142.86% |
| SRPT | Sarepta Therapeutics Inc | $3.18B | +27663.62% |
| PTCT | PTC Therapeutics Inc | $2.87B | +24957.68% |
| CRSP | CRISPR Therapeutics AG | $2.73B | +23706.29% |
| FTRE | Fortrea Holdings Inc | $2.68B | +23335.81% |
| HALO | Halozyme Therapeutics Inc | $2.67B | +23242.52% |
| NBP | NovaBridge Biosciences. | $2.61B | +22720.67% |
| EXEL | Exelixis Inc | $2.59B | +22551.47% |
| TECH | Bio-Techne Corp | $2.55B | +22175.99% |
| ENLV | Enlivex Ltd | $2.33B | +20223.13% |
| ARWR | Arrowhead Pharmaceuticals Inc | $2.27B | +19710.17% |
| RVMD | Revolution Medicines Inc | $2.25B | +19583.29% |
| INSM | Insmed Inc | $2.08B | +18029.81% |
| ASND | Ascendis Pharma A/S | $2.01B | +17414.13% |
| INVA | Innoviva Inc | $1.84B | +15940.06% |
| TLX | Telix Pharmaceuticals Ltd | $1.77B | +15366.50% |
| KYMR | Kymera Therapeutics Inc | $1.67B | +14476.56% |
| ACAD | Acadia Pharmaceuticals Inc | $1.61B | +13919.48% |
| LEGN | Legend Biotech Corp | $1.60B | +13845.41% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $1.53B | +13280.83% |
| TGTX | TG Therapeutics Inc | $1.53B | +13252.29% |
| GPCR | Structure Therapeutics Inc | $1.51B | +13071.39% |
| BEAM | Beam Therapeutics Inc | $1.48B | +12832.73% |
| PRAX | Praxis Precision Medicines Inc | $1.46B | +12652.86% |
| CRNX | Crinetics Pharmaceuticals Inc | $1.40B | +12138.63% |
| KRYS | Krystal Biotech Inc | $1.40B | +12100.59% |
| XENE | Xenon Pharmaceuticals Inc | $1.39B | +12011.88% |
| BBIO | BridgeBio Pharma Inc | $1.37B | +11873.63% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.34B | +11598.88% |
| NUVL | Nuvalent Inc - Class A | $1.33B | +11525.75% |
| ABCL | AbCellera Biologics Inc | $1.31B | +11315.83% |
| RARE | Ultragenyx Pharmaceutical Inc | $1.30B | +11218.78% |
| APGE | Apogee Therapeutics Inc | $1.29B | +11198.29% |
| CYTK | Cytokinetics Inc | $1.27B | +11022.08% |
| HRMY | Harmony Biosciences Holdings Inc | $1.27B | +11007.63% |
| DNLI | Denali Therapeutics Inc | $1.27B | +10956.97% |
| DNTH | Dianthus Therapeutics Inc | $1.25B | +10789.82% |
| MDGL | Madrigal Pharmaceuticals Inc | $1.23B | +10619.01% |
| AGIO | Agios Pharmaceuticals Inc | $1.18B | +10249.26% |
| CAI | Caris Life Sciences Inc - Class A | $1.16B | +10051.86% |
| CPRX | Catalyst Pharmaceuticals Inc | $1.15B | +9922.79% |
| CVAC | CureVac N.V. | $1.14B | +9844.27% |
| CGON | Cg Oncology Inc | $1.14B | +9814.95% |
| ZLAB | Zai Lab Ltd | $1.10B | +9469.76% |
| APLS | Apellis Pharmaceuticals Inc | $1.08B | +9354.43% |
| DYN | Dyne Therapeutics Inc | $1.08B | +9331.88% |
| IMCR | Immunocore Holdings plc | $1.07B | +9263.28% |
| NVAX | Novavax Inc | $1.04B | +9010.59% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $1.03B | +8922.49% |
| IDYA | Ideaya Biosciences Inc | $1.03B | +8898.67% |
| JANX | Janux Therapeutics Inc | $1.03B | +8880.13% |
| VIR | Vir Biotechnology Inc | $1.03B | +8857.07% |
| TERN | Terns Pharmaceuticals Inc | $1.03B | +8852.65% |
| AKRO | Akero Therapeutics Inc | $1.01B | +8682.33% |
| RCUS | Arcus Biosciences Inc | $997.00M | +8607.42% |
| IMVT | Immunovant Inc | $957.01M | +8258.20% |
| FOLD | Amicus Therapeutics Inc | $949.87M | +8195.81% |
| IOVA | Iovance Biotherapeutics Inc | $925.66M | +7984.41% |
| MRUS | Merus N.V | $904.20M | +7796.91% |
| COGT | Cogent Biosciences Inc | $903.01M | +7786.52% |
| MIRM | Mirum Pharmaceuticals Inc | $890.92M | +7680.93% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $849.19M | +7316.52% |
| CRMD | CorMedix Inc | $815.64M | +7023.47% |
| CORT | Corcept Therapeutics Inc | $814.88M | +7016.86% |
| VRDN | Viridian Therapeutics Inc | $789.02M | +6790.98% |
| MESO | Mesoblast Ltd | $782.31M | +6732.38% |
| BLTE | Belite Bio Inc | $780.56M | +6717.08% |
| QURE | uniQure N.V. | $778.71M | +6700.93% |
| SYRE | Spyre Therapeutics Inc | $763.95M | +6572.08% |
| NKTR | Nektar Therapeutics | $763.27M | +6566.12% |
| NTLA | Intellia Therapeutics Inc | $758.78M | +6526.89% |
| IRON | Disc Medicine Inc | $750.21M | +6452.08% |
| ZBIO | Zenas Biopharma Inc | $747.68M | +6429.97% |
| MNKD | Mannkind Corp | $744.40M | +6401.34% |
| XNCR | Xencor Inc | $736.85M | +6335.34% |
| GLUE | Monte Rosa Therapeutics Inc | $736.43M | +6331.69% |
| NAMS | NewAmsterdam Pharma Company NV | $732.64M | +6298.63% |
| OCUL | Ocular Therapeutix Inc | $732.53M | +6297.63% |
| AUPH | Aurinia Pharmaceuticals Inc | $724.00M | +6223.12% |
| AXSM | Axsome Therapeutics Inc | $713.61M | +6132.38% |
| RLAY | Relay Therapeutics Inc | $699.61M | +6010.16% |
| PTGX | Protagonist Therapeutics Inc | $697.46M | +5991.34% |
| ALMS | Alumis Inc | $671.59M | +5765.40% |
| ADMA | Adma Biologics Inc | $665.18M | +5709.47% |
| MLYS | Mineralys Therapeutics Inc | $652.86M | +5601.85% |
| KURA | Kura Oncology Inc | $652.55M | +5599.14% |
| BCYC | Bicycle Therapeutics Plc | $652.40M | +5597.78% |
| SMMT | Summit Therapeutics Inc | $647.86M | +5558.13% |
| ARVN | Arvinas Inc | $647.50M | +5555.02% |
| IBRX | ImmunityBio Inc | $646.64M | +5547.48% |
| CNTA | Centessa Pharmaceuticals plc | $641.76M | +5504.92% |
| VERA | Vera Therapeutics Inc - Class A | $621.74M | +5330.03% |
| IMNM | Immunome Inc | $619.79M | +5313.03% |
| NUVB | Nuvation Bio Inc - Class A | $610.24M | +5229.62% |
| SLNO | Soleno Therapeutics Inc | $608.39M | +5213.43% |
| VKTX | Viking Therapeutics Inc | $608.24M | +5212.16% |
| ACLX | Arcellx Inc | $603.99M | +5175.02% |
| THAR | Tharimmune Inc | $584.65M | +5006.15% |
| WVE | Wave Life Sciences Ltd | $583.54M | +4996.45% |
| TARS | Tarsus Pharmaceuticals Inc | $581.13M | +4975.41% |
| VRNA | Verona Pharma Plc | $572.87M | +4903.24% |
| SEPN | Septerna Inc | $569.69M | +4875.44% |
| TVTX | Travere Therapeutics Inc | $555.19M | +4748.80% |
| BCAX | Bicara Therapeutics Inc | $553.60M | +4734.93% |
| PRTC | PureTech Health plc American Depositary Shares | $553.24M | +4731.81% |
| ABVX | Abivax | $547.14M | +4678.53% |
| IMTX | Immatics N.V | $543.83M | +4649.61% |
| NRIX | Nurix Therapeutics Inc | $535.54M | +4577.21% |
| GLTO | Galecto Inc | $535.44M | +4576.35% |
| SRRK | Scholar Rock Holding Corp | $535.25M | +4574.71% |
| GERN | Geron Corp | $534.12M | +4564.80% |
| OLMA | Olema Pharmaceuticals Inc | $530.64M | +4534.45% |
| AUTL | Autolus Therapeutics plc | $527.07M | +4503.19% |
| CDTX | Cidara Therapeutics Inc | $518.65M | +4429.69% |
| EWTX | Edgewise Therapeutics Inc | $518.52M | +4428.58% |
| FDMT | 4D Molecular Therapeutics Inc | $512.90M | +4379.52% |
| CLDX | Celldex Therapeutics Inc | $511.25M | +4365.10% |
| DAWN | Day One Biopharmaceuticals Inc | $507.83M | +4335.17% |
| VOR | Vor Biopharma Inc | $506.75M | +4325.73% |
| RIGL | Rigel Pharmaceuticals | $504.61M | +4307.06% |
| ARDX | Ardelyx Inc | $504.51M | +4306.17% |
| ORKA | ARCA biopharma Inc | $504.48M | +4305.94% |
| RAPP | Rapport Therapeutics Inc | $497.60M | +4245.83% |
| PHAR | Pharming Group N.V. | $489.37M | +4173.93% |
| VCEL | Vericel Corp | $485.63M | +4141.28% |
| ZYME | Zymeworks BC Inc | $478.21M | +4076.55% |
| SNDX | Syndax Pharmaceuticals Inc | $472.67M | +4028.10% |
| TBPH | Theravance Biopharma Inc | $472.31M | +4025.00% |
| BHVN | Biohaven Ltd | $466.41M | +3973.41% |
| ELVN | Enliven Therapeutics Inc | $464.85M | +3959.84% |
| RVNC | Revance Therapeutics Inc | $461.56M | +3931.13% |
| ERAS | Erasca Inc | $461.23M | +3928.24% |
| ARQT | Arcutis Biotherapeutics Inc | $460.00M | +3917.49% |
| MBX | MBX Biosciences Inc | $452.70M | +3853.72% |
| STOK | Stoke Therapeutics Inc | $443.28M | +3771.41% |
| RYTM | Rhythm Pharmaceuticals Inc | $442.32M | +3763.02% |
| ORIC | ORIC Pharmaceuticals Inc | $436.76M | +3714.52% |
| SLRN | Acelyrin Inc | $436.50M | +3712.26% |
| TNGX | Tango Therapeutics Inc | $435.79M | +3706.04% |
| VNDA | Vanda Pharmaceuticals Inc | $433.52M | +3686.24% |
| SLDB | Solid Biosciences Inc | $422.89M | +3593.39% |
| MAZE | Maze Therapeutics Inc | $419.71M | +3565.59% |
| MPLT | MapLight Therapeutics Inc | $418.79M | +3557.54% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $417.65M | +3547.56% |
| TYRA | Tyra Biosciences Inc | $412.04M | +3498.60% |
| CELC | Celcuity Inc | $410.16M | +3482.22% |
| CGEM | Cullinan Oncology Inc | $402.98M | +3419.51% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $401.29M | +3404.74% |
| MLTX | MoonLake Immunotherapeutics - Class A | $400.37M | +3396.72% |
| ALLO | Allogene Therapeutics Inc | $395.96M | +3358.15% |
| LBRX | LB Pharmaceuticals Inc | $393.48M | +3336.52% |
| SANA | Sana Biotechnology Inc | $373.59M | +3162.82% |
| VALN | Valneva SE | $372.40M | +3152.41% |
| NKTX | Nkarta Inc | $372.07M | +3149.55% |
| CTMX | CytomX Therapeutics Inc | $359.36M | +3038.50% |
| FBIO | Fortress Biotech Inc | $356.87M | +3016.80% |
| PROK | ProKidney Corp - Class A | $351.61M | +2970.81% |
| LYEL | Lyell Immunopharma Inc | $350.63M | +2962.24% |
| PRTA | Prothena Corporation plc | $349.89M | +2955.84% |
| AVBP | ArriVent BioPharma Inc | $349.30M | +2950.61% |
| FULC | Fulcrum Therapeutics Inc | $346.77M | +2928.56% |
| RGNX | Regenxbio Inc | $341.89M | +2885.97% |
| TRDA | Entrada Therapeutics Inc | $335.52M | +2830.29% |
| REPL | Replimune Group Inc | $332.39M | +2802.95% |
| ANAB | AnaptysBio Inc | $329.68M | +2779.34% |
| KALV | KalVista Pharmaceuticals Inc | $328.92M | +2772.64% |
| CCCC | C4 Therapeutics Inc | $328.86M | +2772.15% |
| IPSC | Century Therapeutics Inc | $326.55M | +2751.99% |
| CAPR | Capricor Therapeutics Inc | $326.28M | +2749.64% |
| CBUS | Cibus Global Ltd. Class A | $324.20M | +2731.46% |
| EVMN | Evommune Inc | $322.45M | +2716.20% |
| JBIO | Jade Biosciences Inc | $319.43M | +2689.81% |
| UPB | Upstream Bio Inc | $318.05M | +2677.76% |
| ENTA | Enanta Pharmaceuticals Inc | $314.70M | +2648.51% |
| KROS | Keros Therapeutics Inc | $312.29M | +2627.45% |
| DRUG | Bright Minds Biosciences Inc | $312.15M | +2626.16% |
| MDXG | Mimedx Group Inc | $308.68M | +2595.86% |
| ENGN | enGene Holdings Inc | $307.52M | +2585.80% |
| KOD | Kodiak Sciences Inc | $306.01M | +2572.54% |
| PHAT | Phathom Pharmaceuticals Inc | $305.12M | +2564.80% |
| SION | Sionna Therapeutics Inc | $305.04M | +2564.10% |
| TSHA | Taysha Gene Therapies Inc | $300.35M | +2523.15% |
| PRME | Prime Medicine Inc | $294.73M | +2474.06% |
| OABI | OmniAb Inc | $293.65M | +2464.63% |
| RNA | Atrium Therapeutics Inc | $292.36M | +2453.36% |
| CLLS | Cellectis | $289.19M | +2425.65% |
| RNAC | Cartesian Therapeutics Inc | $288.39M | +2418.70% |
| EYPT | EyePoint Pharmaceuticals Inc | $288.22M | +2417.18% |
| SPRY | ARS Pharmaceuticals Inc | $287.57M | +2411.54% |
| OMER | Omeros Corporation | $286.17M | +2399.33% |
| RCKT | Rocket Pharmaceuticals Inc | $285.41M | +2392.64% |
| FATE | Fate Therapeutics Inc | $284.92M | +2388.35% |
| ALT | Altimmune Inc | $279.93M | +2344.79% |
| THRD | Third Harmonic Bio Inc | $279.84M | +2343.98% |
| ZVRA | Zevra Therapeutics Inc | $278.58M | +2333.00% |
| ABUS | Arbutus Biopharma Corp | $277.16M | +2320.65% |
| ANRO | Alto Neuroscience Inc | $276.26M | +2312.74% |
| GHRS | GH Research PLC | $275.27M | +2304.08% |
| LENZ | LENZ Therapeutics Inc | $272.54M | +2280.22% |
| SEER | Seer Inc - Class A | $272.13M | +2276.70% |
| ATXS | Astria Therapeutics Inc | $271.87M | +2274.38% |
| XOMA | XOMA Royalty Corp | $271.86M | +2274.31% |
| XFOR | X4 Pharmaceuticals Inc | $270.28M | +2260.53% |
| TRML | Tourmaline Bio Inc | $269.30M | +2251.92% |
| ORMP | Oramed Pharmaceuticals Inc | $268.85M | +2248.01% |
| LXRX | Lexicon Pharmaceuticals Inc | $268.82M | +2247.76% |
| AVIR | Atea Pharmaceuticals Inc | $267.08M | +2232.54% |
| DBVT | DBV Technologies | $266.40M | +2226.64% |
| CHRS | Coherus Biosciences Inc | $266.02M | +2223.34% |
| ATAI | ATAI Life Sciences N.V. | $264.88M | +2213.34% |
| PVLA | Palvella Therapeutics Inc | $263.76M | +2203.57% |
| NGNE | Neoleukin Therapeutics Inc | $263.14M | +2198.17% |
| ANNX | Annexon Inc | $262.89M | +2195.97% |
| TCRX | Tscan Therapeutics Inc | $262.23M | +2190.17% |
| CTNM | Contineum Therapeutics Inc - Class A | $261.35M | +2182.52% |
| PHVS | Pharvaris NV | $259.79M | +2168.89% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $257.91M | +2152.51% |
| KYTX | Kyverna Therapeutics Inc | $257.02M | +2144.75% |
| URGN | UroGen Pharma Ltd | $253.69M | +2115.63% |
| CRVS | Corvus Pharmaceuticals Inc | $253.19M | +2111.31% |
| ZNTL | Zentalis Pharmaceuticals Inc | $253.07M | +2110.18% |
| LXEO | Lexeo Therapeutics Inc | $250.36M | +2086.52% |
| SABS | SAB Biotherapeutics Inc | $248.47M | +2070.05% |
| TECX | AvroBio Inc | $246.58M | +2053.51% |
| HRTX | Heron Therapeutics Inc | $246.22M | +2050.36% |
| ARCT | Arcturus Therapeutics Holdings Inc | $245.41M | +2043.33% |
| MGTX | MeiraGTx Holdings plc | $244.66M | +2036.72% |
| OCS | Oculis Holding AG | $243.26M | +2024.58% |
| STRO | Sutro Biopharma Inc | $241.99M | +2013.43% |
| IVVD | Invivyd Inc | $241.74M | +2011.28% |
| ALEC | Alector Inc | $239.92M | +1995.34% |
| ASMB | Assembly Biosciences Inc | $235.51M | +1956.84% |
| RLMD | Relmada Therapeutics Inc | $235.36M | +1955.57% |
| DSGN | Design Therapeutics Inc | $230.44M | +1912.59% |
| ZURA | Zura Bio Ltd - Class A | $228.64M | +1896.86% |
| VSTM | Verastem Inc | $227.81M | +1889.59% |
| OVID | Ovid Therapeutics Inc | $225.63M | +1870.55% |
| FHTX | Foghorn Therapeutics Inc | $222.17M | +1840.32% |
| SVRA | Savara Inc | $221.65M | +1835.76% |
| VYGR | Voyager Therapeutics Inc | $219.32M | +1815.50% |
| MGNX | Macrogenics Inc | $217.87M | +1802.82% |
| IMRX | Immuneering Corp Class A | $214.81M | +1776.07% |
| VTYX | Ventyx Biosciences Inc | $211.47M | +1746.86% |
| LRMR | Larimar Therapeutics Inc | $208.51M | +1721.06% |
| IMAB | I-Mab | $206.71M | +1705.31% |
| SNSE | Sensei Biotherapeutics Inc | $205.38M | +1693.72% |
| CMPX | Compass Therapeutics Inc | $205.17M | +1691.88% |
| PLRX | Pliant Therapeutics Inc | $202.60M | +1669.40% |
| CADL | Candel Therapeutics Inc | $201.92M | +1663.49% |
| TIL | Instil Bio Inc | $200.43M | +1650.46% |
| CBIO | N/A | $199.13M | +1639.13% |
| ACRS | Aclaris Therapeutics Inc | $198.72M | +1635.55% |
| ABEO | Abeona Therapeutics Inc | $198.49M | +1633.57% |
| MGX | Metagenomi Inc | $196.95M | +1620.11% |
| ABSI | Absci Corp | $195.59M | +1608.24% |
| MIST | Milestone Pharmaceuticals Inc | $193.73M | +1592.00% |
| PBYI | Puma Biotechnology Inc | $192.70M | +1582.96% |
| TARA | Protara Therapeutics Inc | $191.92M | +1576.18% |
| IMUX | Immunic Inc | $189.74M | +1557.14% |
| BNTC | Benitec Biopharma Inc | $187.00M | +1533.19% |
| AGEN | Agenus Inc | $186.46M | +1528.44% |
| INBX | Inhibrx Biosciences Inc | $183.97M | +1506.70% |
| KRRO | Korro Bio Inc | $183.62M | +1503.69% |
| VXRT | Vaxart Inc | $180.06M | +1472.53% |
| NBY | Stablecoin Development Corp | $179.74M | +1469.81% |
| TRVI | Trevi Therapeutics Inc | $179.61M | +1468.61% |
| IVA | Inventiva | $178.52M | +1459.11% |
| ALXO | Alx Oncology Holdings Inc | $178.33M | +1457.45% |
| NAUT | Nautilus Biotechnology Inc | $177.78M | +1452.66% |
| HLVX | HilleVax Inc | $174.91M | +1427.63% |
| IKT | Inhibikase Therapeutics Inc | $173.33M | +1413.82% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $172.19M | +1403.82% |
| AURA | Aura Biosciences Inc | $169.43M | +1379.74% |
| ACET | Adicet Bio Inc | $169.38M | +1379.32% |
| RAPT | RAPT Therapeutics Inc | $165.74M | +1347.50% |
| XLO | Xilio Therapeutics Inc | $163.49M | +1327.83% |
| GYRE | Gyre Therapeutics Inc | $162.01M | +1314.98% |
| RNAZ | TransCode Therapeutics Inc | $157.16M | +1272.62% |
| CGEN | Compugen Ltd | $156.57M | +1267.42% |
| PEPG | PepGen Inc | $156.29M | +1265.02% |
| NMRA | Neumora Therapeutics Inc | $153.88M | +1243.90% |
| CLYM | Eliem Therapeutics Inc | $152.37M | +1230.76% |
| EDIT | Editas Medicine Inc | $149.34M | +1204.26% |
| CRBU | Caribou Biosciences Inc | $149.00M | +1201.29% |
| CABA | Cabaletta Bio Inc | $148.15M | +1193.85% |
| IMMP | Immutep Ltd | $147.20M | +1185.61% |
| ELDN | Eledon Pharmaceuticals Inc | $146.67M | +1180.93% |
| CMRX | Chimerix Inc | $146.01M | +1175.18% |
| OPT | Opthea Ltd | $145.77M | +1173.10% |
| PTHS | Channel Therapeutics Corporation | $145.38M | +1169.68% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $144.48M | +1161.83% |
| DTIL | Precision Biosciences Inc | $143.89M | +1156.69% |
| BOLD | Boundless Bio Inc | $140.97M | +1131.18% |
| XBIT | XBiotech Inc | $139.84M | +1121.28% |
| PGEN | Precigen Inc | $138.63M | +1110.72% |
| MNPR | Monopar Therapeutics Inc | $137.98M | +1105.10% |
| ACIU | AC Immune SA | $137.42M | +1100.18% |
| IMA | Ikena Oncology Inc | $136.68M | +1093.73% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $135.37M | +1082.27% |
| TNYA | Tenaya Therapeutics Inc | $135.07M | +1079.65% |
| ABOS | Acumen Pharmaceuticals Inc | $133.63M | +1067.07% |
| PALI | Palisade Bio Inc | $133.31M | +1064.32% |
| AVXL | Anavex Life Sciences Corporation | $132.99M | +1061.48% |
| BDTX | Black Diamond Therapeutics Inc | $132.92M | +1060.89% |
| CTXR | Citius Pharmaceuticals Inc | $132.54M | +1057.56% |
| KPTI | Karyopharm Therapeutics Inc | $131.42M | +1047.75% |
| ARTV | Artiva Biotherapeutics Inc | $130.94M | +1043.58% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $130.63M | +1040.90% |
| CDXS | Codexis Inc | $129.37M | +1029.87% |
| GOSS | Gossamer Bio Inc | $128.90M | +1025.76% |
| WHWK | Whitehawk Therapeutics Inc | $127.23M | +1011.19% |
| RPTX | Repare Therapeutics Inc | $126.75M | +1006.96% |
| RZLT | Rezolute Inc | $125.46M | +995.71% |
| TENX | Tenax Therapeutics Inc | $123.18M | +975.79% |
| GBIO | Generation Bio Company | $121.90M | +964.59% |
| SRZN | Surrozen Inc | $120.71M | +954.23% |
| PRLD | Prelude Therapeutics Inc | $119.64M | +944.91% |
| MCRB | Seres Therapeutics Inc | $117.62M | +927.23% |
| YMAB | Y-Mabs Therapeutics Inc | $117.21M | +923.68% |
| SGMT | Sagimet Biosciences Inc - Class A | $116.48M | +917.31% |
| AVTX | Avalo Therapeutics Inc | $116.46M | +917.10% |
| SLN | Silence Therapeutics Plc | $115.12M | +905.44% |
| NAGE | Niagen Bioscience Inc | $114.33M | +898.51% |
| SLS | SELLAS Life Sciences Group Inc | $114.18M | +897.18% |
| HUMA | Humacyte Inc | $110.56M | +865.56% |
| EPIX | Essa Pharma Inc | $110.50M | +865.08% |
| KLRS | Kalaris Therapeutics Inc | $109.81M | +859.00% |
| FGEN | FibroGen Inc | $109.63M | +857.46% |
| LCTX | Lineage Cell Therapeutics Inc | $109.53M | +856.62% |
| SAVA | Cassava Sciences Inc. | $108.37M | +846.44% |
| ACRV | Acrivon Therapeutics Inc | $107.83M | +841.76% |
| CELU | Celularity Inc - Class A | $107.33M | +837.37% |
| DRTS | Alpha Tau Medical Ltd | $105.65M | +822.72% |
| CAMP | CAMP4 Therapeutics Corp | $105.46M | +821.02% |
| PLX | Protalix BioTherapeutics Inc | $102.34M | +793.76% |
| STTK | Shattuck Labs Inc | $102.12M | +791.89% |
| OBIO | Orchestra BioMed Holdings Inc | $100.66M | +779.11% |
| VTVT | vTv Therapeutics Inc - Class A | $99.49M | +768.94% |
| GUTS | Fractyl Health Inc | $99.39M | +767.99% |
| PRQR | ProQR Therapeutics N.V | $99.14M | +765.83% |
| AARD | Aardvark Therapeutics Inc | $98.59M | +761.05% |
| PMVP | PMV Pharmaceuticals Inc | $96.56M | +743.34% |
| IMMX | Immix Biopharma Inc | $95.82M | +736.82% |
| DWTX | Virios Therapeutics Inc | $95.21M | +731.51% |
| NERV | Minerva Neurosciences Inc | $94.03M | +721.20% |
| BRNS | Barinthus Biotherapeutics Plc. | $92.14M | +704.74% |
| ANTX | AN2 Therapeutics Inc | $87.49M | +664.11% |
| MOLN | Molecular Partners AG | $87.40M | +663.29% |
| EPRX | Eupraxia Pharmaceuticals Inc | $86.15M | +652.40% |
| IBIO | iBio Inc | $85.83M | +649.64% |
| FBRX | Forte Biosciences Inc | $82.78M | +622.96% |
| MDWD | MediWound Ltd | $79.98M | +598.53% |
| ATYR | Atyr Pharma Inc | $79.65M | +595.67% |
| ADAG | Adagene Inc | $78.26M | +583.52% |
| ADVM | Adverum Biotechnologies Inc | $72.40M | +532.32% |
| FENC | Fennec Pharmaceuticals Inc | $71.82M | +527.27% |
| ATHA | Athira Pharma Inc | $71.59M | +525.24% |
| HYPD | Eyenovia Inc | $70.07M | +511.93% |
| ARMP | Armata Pharmaceuticals Inc | $69.80M | +509.61% |
| ACOG | Alpha Cognition Inc | $69.25M | +504.79% |
| KZR | Kezar Life Sciences Inc | $68.00M | +493.88% |
| NBTX | Nanobiotix | $67.76M | +491.79% |
| PMN | ProMIS Neurosciences Inc | $67.41M | +488.75% |
| IRD | Ocuphire Pharma Inc | $66.79M | +483.29% |
| GRCE | Acasti Pharma Inc | $66.65M | +482.13% |
| ALDX | Aldeyra Therapeutics Inc | $66.48M | +480.64% |
| MURA | Mural Oncology plc | $65.76M | +474.31% |
| ALGS | Aligos Therapeutics Inc | $64.56M | +463.83% |
| UNCY | Unicycive Therapeutics Inc | $64.41M | +462.50% |
| PYXS | Pyxis Oncology Inc | $64.30M | +461.57% |
| QTTB | Q32 Bio Inc | $63.67M | +456.11% |
| EQ | Equillium Inc | $63.08M | +450.94% |
| IPHA | Innate Pharma | $62.69M | +447.53% |
| MRSN | Mersana Therapeutics Inc | $62.69M | +447.48% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $62.12M | +442.51% |
| HOOK | Hookipa Pharma Inc | $61.26M | +434.99% |
| CNTB | Connect Biopharma Holdings Ltd | $60.07M | +424.59% |
| SGMO | Sangamo Therapeutics Inc | $59.97M | +423.71% |
| KLTO | Klotho Neurosciences Inc Com | $59.74M | +421.72% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $59.74M | +421.72% |
| SPRO | Spero Therapeutics Inc | $59.02M | +415.47% |
| CNTX | Context Therapeutics Inc | $58.86M | +414.05% |
| HOWL | Werewolf Therapeutics Inc | $58.02M | +406.74% |
| LITS | Lite Strategy Inc | $57.79M | +404.71% |
| OCGN | Ocugen Inc | $56.91M | +396.99% |
| ATHE | Alterity Therapeutics Ltd | $56.86M | +396.62% |
| KTTA | Pasithea Therapeutics Corp | $56.35M | +392.18% |
| SPRB | Spruce Biosciences Inc | $56.17M | +390.53% |
| PMCB | PharmaCyte Biotech Inc | $55.87M | +387.98% |
| RLYB | Rallybio Corp | $54.47M | +375.74% |
| COYA | Coya Therapeutics Inc | $53.27M | +365.25% |
| DMAC | DiaMedica Therapeutics Inc | $53.08M | +363.58% |
| LVTX | LAVA Therapeutics NV | $51.91M | +353.41% |
| RANI | Rani Therapeutics Holdings Inc Class A | $51.88M | +353.09% |
| PHXM | PHAXIAM Therapeutics SA ADR | $51.31M | +348.10% |
| INO | Inovio Pharmaceuticals Inc | $49.78M | +334.73% |
| JAGX | Jaguar Health Inc | $49.47M | +332.07% |
| CRDF | Cardiff Oncology Inc | $49.17M | +329.45% |
| IFRX | InflaRx N.V. | $48.94M | +327.43% |
| VTGN | VistaGen Therapeutics Inc | $48.56M | +324.14% |
| BOLT | Bolt Biotherapeutics Inc | $48.03M | +319.45% |
| GRDX | Entero Therapeutics Inc | $47.97M | +318.91% |
| APRE | Aprea Therapeutics Inc | $47.61M | +315.83% |
| BMEA | Biomea Fusion Inc | $46.38M | +305.11% |
| ATNM | Actinium Pharmaceuticals Inc | $45.44M | +296.84% |
| AKTX | Akari Therapeutics Plc | $45.38M | +296.30% |
| ICCC | Immucell Corp | $44.11M | +285.23% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $43.47M | +279.65% |
| VERU | Veru Inc | $43.08M | +276.27% |
| MNOV | Medicinova Inc | $42.70M | +272.97% |
| VANI | Vivani Medical Inc | $42.35M | +269.90% |
| ACHV | Achieve Life Sciences Inc | $41.79M | +264.98% |
| MREO | Mereo Biopharma Group Plc | $40.61M | +254.71% |
| IOBT | IO Biotech Inc | $39.96M | +248.96% |
| BLRX | Bioline Rx Ltd | $38.80M | +238.84% |
| VRCA | Verrica Pharmaceuticals Inc | $38.79M | +238.74% |
| TOVX | Theriva Biologics Inc | $38.25M | +234.04% |
| SNTI | Senti Biosciences Inc | $38.24M | +233.98% |
| NXTC | Nextcure Inc | $37.98M | +231.68% |
| ATOS | Atossa Therapeutics Inc | $37.94M | +231.38% |
| PASG | Passage Bio Inc | $36.46M | +218.45% |
| CGTX | Cognition Therapeutics Inc | $36.14M | +215.63% |
| LYRA | Lyra Therapeutics Inc | $36.11M | +215.35% |
| MAIA | MAIA Biotechnology Inc | $35.32M | +208.49% |
| ALLR | Allarity Therapeutics Inc | $34.92M | +205.00% |
| NEUP | Neuphoria Therapeutics Inc | $34.81M | +204.01% |
| APLT | Applied Therapeutics Inc | $34.37M | +200.21% |
| ITRM | Iterum Therapeutics Plc | $32.50M | +183.87% |
| GNLX | Genelux Corp | $32.37M | +182.72% |
| GNTA | Genenta Science SpA | $31.89M | +178.51% |
| CUE | Cue Biopharma Inc | $30.88M | +169.67% |
| CING | Cingulate Inc | $30.86M | +169.53% |
| SLGL | Sol-Gel Technologies Ltd | $29.92M | +161.28% |
| HURA | TuHURA Biosciences Inc | $29.70M | +159.43% |
| CRIS | Curis Inc | $29.69M | +159.27% |
| CSBR | Champions Oncology Inc | $28.45M | +148.45% |
| DARE | Dare Bioscience Inc | $27.83M | +143.04% |
| NCNA | NuCana plc | $27.55M | +140.65% |
| HCWB | HCW Biologics Inc | $27.34M | +138.80% |
| SER | AgeX Therapeutics Inc | $27.30M | +138.42% |
| BCTX | BriaCell Therapeutics Corp - New | $27.07M | +136.43% |
| QNCX | Quince Therapeutics Inc | $26.62M | +132.52% |
| INAB | IN8bio Inc | $26.27M | +129.39% |
| PLUR | Pluri Inc | $26.06M | +127.57% |
| VYNE | VYNE Therapeutics Inc | $25.87M | +125.97% |
| INMB | INmune Bio Inc | $25.82M | +125.48% |
| TVRD | Cara Therapeutics Inc | $25.82M | +125.48% |
| CASI | CASI Pharmaceuticals Inc | $25.65M | +124.02% |
| NVCT | Nuvectis Pharma Inc | $25.40M | +121.82% |
| LPCN | Lipocine Inc | $25.36M | +121.47% |
| PDSB | PDS Biotechnology Corporation | $24.66M | +115.40% |
| RNTX | Rein Therapeutics Inc | $24.16M | +110.99% |
| EVAX | Evaxion Biotech A/S | $23.64M | +106.48% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $23.56M | +105.76% |
| MBRX | Moleculin Biotech Inc | $23.36M | +104.04% |
| HYFT | MindWalk Holdings Corp | $23.17M | +102.33% |
| CVM | Cel-Sci Corp | $22.89M | +99.95% |
| ELTX | Elicio Therapeutics Inc | $22.69M | +98.16% |
| PYPD | Polypid Ltd | $22.31M | +94.82% |
| OTLK | Outlook Therapeutics Inc | $21.89M | +91.20% |
| PLRZ | Polyrizon Ltd | $21.44M | +87.22% |
| KPRX | Kiora Pharmaceuticals Inc | $21.23M | +85.39% |
| LGVN | Longeveron Inc - Class A | $21.21M | +85.24% |
| JSPR | Jasper Therapeutics Inc | $21.18M | +85.01% |
| MENS | Jyong Biotech Ltd | $20.78M | +81.47% |
| GNPX | Genprex Inc | $20.31M | +77.35% |
| LPTX | Leap Therapeutics Inc | $20.04M | +75.04% |
| ATRA | Atara Biotherapeutics Inc | $20.00M | +74.65% |
| PSTV | Plus Therapeutics Inc | $19.92M | +73.94% |
| APVO | Aptevo Therapeutics Inc | $19.90M | +73.82% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $19.79M | +72.81% |
| ABVC | ABVC BioPharma Inc | $19.73M | +72.34% |
| SKYE | Skye Bioscience Inc | $19.42M | +69.58% |
| GANX | Gain Therapeutics Inc | $18.74M | +63.65% |
| APM | Aptorum Group Limited Class A Ordinary Shares | $18.69M | +63.24% |
| TTRX | Turn Therapeutics Inc | $18.64M | +62.83% |
| GLMD | Galmed Pharmaceuticals Ltd | $18.63M | +62.68% |
| BYSI | BeyondSpring Inc | $18.41M | +60.75% |
| BDRX | Biodexa Pharmaceuticals Plc | $18.15M | +58.49% |
| EVGN | Evogene Ltd | $17.95M | +56.75% |
| BIVI | BioVie Inc - Class A | $17.51M | +52.97% |
| MRKR | Marker Therapeutics Inc | $17.43M | +52.26% |
| PHIO | Phio Pharmaceuticals Corp | $17.41M | +52.07% |
| IBO | Impact BioMedical Inc | $17.09M | +49.22% |
| MBIO | Mustang Bio Inc | $16.58M | +44.82% |
| ANVS | Annovis Bio Inc | $16.24M | +41.87% |
| GALT | Galectin Therapeutics Inc | $15.76M | +37.63% |
| QNRX | Quoin Pharmaceuticals Ltd | $15.69M | +37.06% |
| ONCT | Oncternal Therapeutics Inc | $15.60M | +36.25% |
| IMRN | Immuron Ltd | $15.12M | +32.07% |
| CRVO | CervoMed Inc | $15.11M | +31.99% |
| PPCB | Propanc Biopharma Inc | $15.11M | +31.98% |
| REVB | Revelation Biosciences Inc | $15.04M | +31.39% |
| CLRB | Cellectar Biosciences Inc | $14.98M | +30.82% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $14.98M | +30.79% |
| ELAB | PMGC Holdings Inc | $14.94M | +30.46% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $14.88M | +30.00% |
| ANIX | Anixa Biosciences Inc | $14.87M | +29.83% |
| ONCO | Onconetix Inc | $14.83M | +29.54% |
| SYBX | Synlogic Inc | $14.61M | +27.61% |
| CMND | Clearmind Medicine Inc | $14.52M | +26.84% |
| MTVA | MetaVia Inc | $14.39M | +25.66% |
| LSTA | Lisata Therapeutics Inc | $14.06M | +22.79% |
| RNXT | RenovoRx Inc | $13.96M | +21.96% |
| ADTX | Aditxt Inc | $13.91M | +21.46% |
| CMMB | Chemomab Therapeutics Ltd | $13.81M | +20.63% |
| YDES | YD Bio Ltd | $13.78M | +20.34% |
| PTN | Palatin Technologies Inc | $13.23M | +15.51% |
| ENTX | Entera Bio Ltd | $13.13M | +14.66% |
| PBM | Psyence Biomedical Ltd | $12.81M | +11.88% |
| XCUR | Exicure Inc | $12.76M | +11.40% |
| ARTL | Artelo Biosciences Inc | $12.52M | +9.33% |
| EDSA | Edesa Biotech Inc | $12.38M | +8.16% |
| KALA | Kala Bio Inc | $12.32M | +7.58% |
| INTS | Intensity Therapeutics Inc | $12.29M | +7.34% |
| AZTR | Azitra Inc | $12.13M | +5.91% |
| NRXP | NRX Pharmaceuticals Inc | $11.90M | +3.96% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $11.64M | +1.67% |
| SCNI | Scinai Immunotherapeutics Ltd | $11.63M | +1.54% |
| GRI | GRI Bio Inc | $11.34M | -0.97% |
| ICU | SeaStar Medical Holding Corp | $11.26M | -1.63% |
| TPST | Tempest Therapeutics Inc | $10.75M | -6.13% |
| ERNA | Ernexa Therapeutics Inc | $10.54M | -7.92% |
| GLSI | Greenwich LifeSciences Inc | $10.51M | -8.25% |
| INKT | MiNK Therapeutics Inc | $10.38M | -9.37% |
| NNVC | NanoViricides Inc | $10.22M | -10.75% |
| HIND | ReShape Lifesciences Inc | $10.19M | -11.04% |
| LNAI | Lunai Bioworks Inc | $9.86M | -13.88% |
| CLDI | Calidi Biotherapeutics Inc | $9.59M | -16.24% |
| CDIO | Cardio Diagnostics Holdings Inc | $9.56M | -16.51% |
| ACXP | Acurx Pharmaceuticals Inc | $9.54M | -16.68% |
| CANF | Can-Fite Biopharma Ltd | $9.51M | -16.91% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $9.42M | -17.71% |
| IGC | IGC Pharma Inc | $9.19M | -19.78% |
| CLGN | CollPlant Biotechnologies Ltd New | $9.18M | -19.80% |
| ACTU | Actuate Therapeutics Inc | $8.91M | -22.17% |
| NRXS | Neuraxis Inc | $8.75M | -23.62% |
| AEON | AEON Biopharma Inc - Class A | $8.63M | -24.63% |
| CALC | CalciMedica Inc | $8.61M | -24.81% |
| AIM | AIM ImmunoTech Inc. | $8.59M | -25.02% |
| BCAB | BioAtla Inc | $8.57M | -25.19% |
| CDT | CDT Equity Inc | $8.55M | -25.31% |
| CYCN | Cyclerion Therapeutics Inc | $8.51M | -25.72% |
| SLRX | Decoy Therapeutics Inc | $8.42M | -26.43% |
| CURX | Curanex Pharmaceuticals Inc | $8.41M | -26.54% |
| ONCY | Oncolytics Biotech Inc | $8.16M | -28.72% |
| TRAW | Traws Pharma Inc | $8.16M | -28.77% |
| IMNN | Imunon Inc | $8.02M | -29.97% |
| GDTC | CytoMed Therapeutics Ltd | $7.98M | -30.26% |
| XBIO | Xenetic Biosciences Inc | $7.91M | -30.93% |
| DYAI | Dyadic International Inc DE | $7.81M | -31.79% |
| BGMS | Bio Green Med Solution Inc | $7.56M | -33.94% |
| OGEN | Oragenics Inc | $7.49M | -34.59% |
| DRMA | Dermata Therapeutics Inc | $7.47M | -34.80% |
| COCP | Cocrystal Pharma Inc | $7.43M | -35.14% |
| VIVS | VivoSim Labs Inc | $7.39M | -35.49% |
| TELO | Telomir Pharmaceuticals Inc | $7.34M | -35.88% |
| OSTX | OS Therapies Inc | $7.30M | -36.25% |
| LTRN | Lantern Pharma Inc | $7.22M | -36.92% |
| ASBP | Aspire Biopharma Holdings Inc | $7.12M | -37.84% |
| SILO | SILO Pharma Inc | $7.02M | -38.71% |
| SNGX | Soligenix Inc | $6.92M | -39.54% |
| NTRB | Nutriband Inc | $6.89M | -39.81% |
| INDP | Indaptus Therapeutics Inc | $6.84M | -40.26% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $6.76M | -40.93% |
| GTBP | GT Biopharma Inc | $6.76M | -40.97% |
| APLM | Apollomics Inc - Class A | $6.71M | -41.36% |
| CELZ | Creative Medical Technology Holdings Inc | $6.44M | -43.75% |
| FBLG | FibroBiologics Inc | $5.94M | -48.14% |
| MTNB | Matinas Biopharma Holdings Inc | $5.87M | -48.70% |
| KAPA | Kairos Pharma Ltd | $5.74M | -49.83% |
| VRAX | Virax Biolabs Group Ltd - Class A | $5.72M | -50.09% |
| HOTH | Hoth Therapeutics Inc | $5.59M | -51.14% |
| ENVB | Enveric Biosciences Inc | $5.52M | -51.78% |
| ADIL | Adial Pharmaceuticals Inc | $5.23M | -54.35% |
| BBLG | Bone Biologics Corp | $4.98M | -56.51% |
| TVGN | Tevogen Bio Holdings Inc | $4.92M | -57.02% |
| LEXX | Lexaria Bioscience Corp | $4.78M | -58.24% |
| ADXN | Addex Therapeutics Ltd | $4.76M | -58.43% |
| CNSP | Cns Pharmaceuticals Inc | $4.65M | -59.36% |
| OKYO | OKYO Pharma Ltd - New | $4.64M | -59.44% |
| BRTX | BioRestorative Therapies Inc | $4.64M | -59.47% |
| SLXN | Silexion Therapeutics Corp | $4.60M | -59.81% |
| PCSA | Processa Pharmaceuticals Inc | $4.52M | -60.52% |
| PULM | Pulmatrix Inc | $4.50M | -60.73% |
| PTIX | Protagenic Therapeutics Inc | $4.43M | -61.30% |
| ALZN | Alzamend Neuro Inc | $4.04M | -64.70% |
| EXOZ | Invizyne Technologies Inc | $4.02M | -64.90% |
| JUNS | Jupiter Neurosciences Inc | $3.95M | -65.51% |
| ESLA | Estrella Immunopharma Inc | $3.66M | -68.06% |
| NTHI | NeOnc Technologies Holdings Inc | $3.33M | -70.92% |
| TTNP | Titan Pharmaceuticals Inc (de) | $3.05M | -73.35% |
| GOVX | Geovax Labs Inc | $2.98M | -73.95% |
| CVKD | Cadrenal Therapeutics Inc | $2.86M | -75.00% |
| LIMN | Liminatus Pharma Inc | $2.79M | -75.63% |
| ENSC | Ensysce Biosciences Inc | $2.17M | -81.07% |
| XRTX | XORTX Therapeutics Inc | $2.15M | -81.21% |
| TCRT | Alaunos Therapeutics Inc | $1.88M | -83.55% |
| BCDA | BioCardia Inc | $1.71M | -85.05% |
| ABP | Abpro Holdings, Inc Common Stock | $1.06M | -90.72% |
| NRSN | NeuroSense Therapeutics Ltd | $1.03M | -91.02% |
| BCLI | Brainstorm Cell Therapeutics Inc | $755000.00 | -93.41% |
| ZVSA | ZyVersa Therapeutics Inc | $742223.00 | -93.52% |