Performance analysis of Karyopharm Therapeutics (KPTI)
Annual Return
Over the past 3 years, KPTI has had an average annual return of -33.14%, underperforming the benchmark SPY, which returned +19.31% annual.
Over the past 5 years, KPTI has had an average annual return of -44.03%, underperforming the benchmark SPY, which returned +12.55% annual.
Over the past 10 years, KPTI has had an average annual return of -23.28%, underperforming the benchmark SPY, which returned +14.95% annual.
Since Nov 6, 2013, KPTI has had an average annual return of -23.91%, underperforming the benchmark SPY, which returned +13.85% annual.
| 2026 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| +1.31% | -27.32% | -21.89% | -74.55% | -47.13% | -58.47% | -19.25% | +104.59% | -2.39% | +2.12% | -29.05% | -64.60% |
| 2014 | 2013 | ||||||||||
| +63.31% | +42.80% |
Monthly Return
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Annually Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -11.44% | +44.28% | -40.92% | +49.35% | +9.57% | +7.41% | -23.65% | +1.31% | |||||
| 2025 | -7.84% | -14.95% | -53.03% | +80.65% | -37.86% | +2.87% | -11.73% | +86.71% | -7.80% | -11.40% | -3.32% | +31.33% | -27.32% |
| 2024 | -13.17% | +54.49% | +30.15% | -31.77% | -5.92% | -10.43% | +13.86% | -23.05% | +9.07% | +19.34% | -14.75% | -19.96% | -21.89% |
| 2023 | -2.93% | -8.46% | +28.80% | -7.96% | -36.89% | -20.81% | +0.54% | -28.81% | +4.64% | -35.09% | -11.44% | +12.29% | -74.55% |
| 2022 | +38.42% | +16.07% | -28.65% | -17.23% | +2.95% | -28.19% | -5.77% | +19.07% | +7.90% | -12.82% | +11.13% | -35.74% | -47.13% |
| 2021 | -1.62% | -9.25% | -23.88% | -11.23% | -0.64% | +11.21% | -19.28% | -30.37% | +0.33% | -6.18% | +27.28% | -7.48% | -58.47% |
| 2020 | -15.76% | +1.18% | +17.56% | +14.78% | -16.14% | +2.44% | -15.26% | -5.23% | -4.01% | +1.51% | +14.64% | -8.89% | -19.25% |
| 2019 | -9.61% | -51.24% | +41.43% | -20.03% | +20.76% | +6.20% | +47.08% | -1.93% | +11.35% | +21.62% | +49.74% | +9.42% | +104.59% |
| 2018 | +23.12% | +24.96% | -9.14% | -2.52% | +42.04% | -8.55% | +4.65% | +18.39% | -19.09% | -38.11% | -1.32% | -9.91% | -2.39% |
| 2017 | +10.11% | +0.19% | +23.82% | -20.40% | -20.56% | +11.46% | -6.74% | +21.09% | +7.43% | -7.02% | +9.61% | -14.21% | +2.12% |
Drawdown analysis of Karyopharm Therapeutics (KPTI)
The maximum drawdown for the KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.
The current KPTI drawdown is -98.94%.
Since Nov 6, 2013 KPTI has experienced the following drawdowns:
- 50% or more: 1 time
- 40% or more: 2 times
- 30% or more: 2 times
- 20% or more: 2 times
- 10% or more: 3 times
| Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -99.50% | Jun 13, 2014 | 2716 | Apr 1, 2025 | Ongoing | Ongoing | Ongoing |
| -43.74% | Mar 6, 2014 | 68 | Jun 12, 2014 | 1 | Jun 13, 2014 | 69 |
| -10.42% | Dec 20, 2013 | 14 | Jan 13, 2014 | 2 | Jan 15, 2014 | 16 |
| -9.08% | Jan 31, 2014 | 3 | Feb 5, 2014 | 5 | Feb 12, 2014 | 8 |
| -8.83% | Mar 4, 2014 | 1 | Mar 5, 2014 | 1 | Mar 6, 2014 | 2 |
| -5.88% | Jan 22, 2014 | 3 | Jan 27, 2014 | 3 | Jan 30, 2014 | 6 |
| -4.87% | Feb 27, 2014 | 2 | Mar 3, 2014 | 1 | Mar 4, 2014 | 3 |
| -4.36% | Feb 13, 2014 | 3 | Feb 19, 2014 | 1 | Feb 20, 2014 | 4 |
| -3.38% | Dec 9, 2013 | 2 | Dec 11, 2013 | 2 | Dec 13, 2013 | 4 |
| -1.60% | Nov 29, 2013 | 4 | Dec 5, 2013 | 1 | Dec 6, 2013 | 5 |
| -1.47% | Nov 8, 2013 | 2 | Nov 12, 2013 | 12 | Nov 29, 2013 | 14 |
| -0.44% | Nov 6, 2013 | 1 | Nov 7, 2013 | 1 | Nov 8, 2013 | 2 |