| VRTX | Vertex Pharmaceuticals Inc | $121.26B | +41083.10% |
| VRNA | Verona Pharma Plc | $77.75B | +26305.83% |
| REGN | Regeneron Pharmaceuticals Inc | $69.10B | +23369.81% |
| ARGX | Argen X SE | $57.12B | +19301.16% |
| ALNY | Alnylam Pharmaceuticals Inc | $36.95B | +12450.04% |
| RVMD | Revolution Medicines Inc | $36.92B | +12439.69% |
| ONC | BeiGene Ltd | $36.03B | +12138.78% |
| MRNA | Moderna Inc | $27.11B | +9106.57% |
| ROIV | Roivant Sciences Ltd | $25.13B | +8436.11% |
| RPRX | Royalty Pharma plc - Class A | $24.60B | +8253.57% |
| INSM | Insmed Inc | $23.78B | +7975.28% |
| BNTX | BioNTech SE | $23.26B | +7800.89% |
| INCY | Incyte Corp | $23.01B | +7715.73% |
| GMAB | Genmab | $18.57B | +6206.76% |
| ASND | Ascendis Pharma A/S | $17.33B | +5785.44% |
| BBIO | BridgeBio Pharma Inc | $16.18B | +5394.36% |
| JAZZ | Jazz Pharmaceuticals plc | $14.81B | +4931.34% |
| EXEL | Exelixis Inc | $14.09B | +4686.52% |
| MDGL | Madrigal Pharmaceuticals Inc | $12.68B | +4206.18% |
| AXSM | Axsome Therapeutics Inc | $12.21B | +4048.28% |
| SMMT | Summit Therapeutics Inc | $11.69B | +3871.90% |
| BMRN | Biomarin Pharmaceutical Inc | $11.39B | +3769.54% |
| TECH | Bio-Techne Corp | $11.19B | +3699.77% |
| ABVX | Abivax | $10.86B | +3587.81% |
| KRYS | Krystal Biotech Inc | $10.31B | +3401.65% |
| CYTK | Cytokinetics Inc | $10.18B | +3359.13% |
| ARWR | Arrowhead Pharmaceuticals Inc | $10.10B | +3328.90% |
| APGE | Apogee Therapeutics Inc | $10.06B | +3315.37% |
| NUVL | Nuvalent Inc - Class A | $9.75B | +3212.12% |
| KYMR | Kymera Therapeutics Inc | $9.38B | +3085.32% |
| CORT | Corcept Therapeutics Inc | $9.35B | +3077.04% |
| IONS | Ionis Pharmaceuticals Inc | $9.08B | +2983.83% |
| HALO | Halozyme Therapeutics Inc | $8.99B | +2952.11% |
| PRAX | Praxis Precision Medicines Inc | $8.87B | +2912.92% |
| CRNX | Crinetics Pharmaceuticals Inc | $8.84B | +2900.97% |
| PTGX | Protagonist Therapeutics Inc | $8.70B | +2854.90% |
| TGTX | TG Therapeutics Inc | $8.64B | +2833.11% |
| PCVX | Vaxcyte Inc | $8.19B | +2681.09% |
| IMVT | Immunovant Inc | $8.13B | +2662.31% |
| IBRX | ImmunityBio Inc | $8.10B | +2649.68% |
| SYRE | Spyre Therapeutics Inc | $8.05B | +2633.11% |
| RYTM | Rhythm Pharmaceuticals Inc | $7.51B | +2449.90% |
| MTSR | Metsera Inc | $7.40B | +2414.88% |
| MIRM | Mirum Pharmaceuticals Inc | $7.37B | +2403.82% |
| MRUS | Merus N.V | $6.83B | +2218.25% |
| COGT | Cogent Biosciences Inc | $6.71B | +2179.44% |
| ACLX | Arcellx Inc | $6.67B | +2163.99% |
| XENE | Xenon Pharmaceuticals Inc | $6.54B | +2122.04% |
| PTCT | PTC Therapeutics Inc | $6.53B | +2119.32% |
| CDTX | Cidara Therapeutics Inc | $6.49B | +2105.69% |
| SRRK | Scholar Rock Holding Corp | $6.44B | +2086.02% |
| CGON | Cg Oncology Inc | $6.42B | +2082.01% |
| CNTA | Centessa Pharmaceuticals plc | $6.27B | +2028.34% |
| TERN | Terns Pharmaceuticals Inc | $5.95B | +1920.02% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $5.93B | +1915.33% |
| BLTE | Belite Bio Inc | $5.88B | +1897.11% |
| ERAS | Erasca Inc | $5.51B | +1770.19% |
| DNTH | Dianthus Therapeutics Inc | $5.45B | +1752.16% |
| APLS | Apellis Pharmaceuticals Inc | $5.25B | +1682.64% |
| TVTX | Travere Therapeutics Inc | $5.24B | +1680.71% |
| CRSP | CRISPR Therapeutics AG | $4.95B | +1581.65% |
| CAI | Caris Life Sciences Inc - Class A | $4.94B | +1576.13% |
| FOLD | Amicus Therapeutics Inc | $4.50B | +1429.81% |
| ACAD | Acadia Pharmaceuticals Inc | $4.43B | +1406.13% |
| CELC | Celcuity Inc | $4.42B | +1402.64% |
| EWTX | Edgewise Therapeutics Inc | $4.39B | +1390.48% |
| VKTX | Viking Therapeutics Inc | $4.38B | +1388.27% |
| AKRO | Akero Therapeutics Inc | $4.38B | +1387.66% |
| TNGX | Tango Therapeutics Inc | $4.36B | +1381.12% |
| ORKA | ARCA biopharma Inc | $4.35B | +1376.41% |
| LEGN | Legend Biotech Corp | $4.26B | +1345.58% |
| DYN | Dyne Therapeutics Inc | $3.96B | +1246.04% |
| CPRX | Catalyst Pharmaceuticals Inc | $3.85B | +1206.75% |
| TLX | Telix Pharmaceuticals Ltd | $3.82B | +1199.04% |
| NAMS | NewAmsterdam Pharma Company NV | $3.73B | +1166.91% |
| RLAY | Relay Therapeutics Inc | $3.69B | +1153.76% |
| DNLI | Denali Therapeutics Inc | $3.65B | +1140.44% |
| ALMS | Alumis Inc | $3.60B | +1123.61% |
| GPCR | Structure Therapeutics Inc | $3.53B | +1097.71% |
| RCUS | Arcus Biosciences Inc | $3.52B | +1094.33% |
| ARQT | Arcutis Biotherapeutics Inc | $3.47B | +1079.78% |
| ELVN | Enliven Therapeutics Inc | $3.24B | +999.37% |
| IDYA | Ideaya Biosciences Inc | $3.23B | +996.29% |
| BEAM | Beam Therapeutics Inc | $3.17B | +976.16% |
| RARE | Ultragenyx Pharmaceutical Inc | $3.12B | +958.68% |
| VERA | Vera Therapeutics Inc - Class A | $3.04B | +931.73% |
| IRON | Disc Medicine Inc | $2.90B | +886.04% |
| MBX | MBX Biosciences Inc | $2.89B | +880.30% |
| SLNO | Soleno Therapeutics Inc | $2.74B | +831.14% |
| KOD | Kodiak Sciences Inc | $2.64B | +795.50% |
| QURE | uniQure N.V. | $2.58B | +777.74% |
| CLDX | Celldex Therapeutics Inc | $2.55B | +766.16% |
| TARS | Tarsus Pharmaceuticals Inc | $2.47B | +740.17% |
| NRIX | Nurix Therapeutics Inc | $2.47B | +740.02% |
| MLYS | Mineralys Therapeutics Inc | $2.43B | +725.93% |
| VCEL | Vericel Corp | $2.38B | +709.42% |
| AGIO | Agios Pharmaceuticals Inc | $2.37B | +703.56% |
| MESO | Mesoblast Ltd | $2.36B | +700.42% |
| ETNB | 89bio Inc | $2.34B | +695.75% |
| TRVI | Trevi Therapeutics Inc | $2.33B | +691.36% |
| SLS | SELLAS Life Sciences Group Inc | $2.32B | +687.70% |
| PHVS | Pharvaris NV | $2.30B | +679.85% |
| ZLAB | Zai Lab Ltd | $2.27B | +670.74% |
| BHVN | Biohaven Ltd | $2.24B | +660.12% |
| DAWN | Day One Biopharmaceuticals Inc | $2.22B | +653.05% |
| OCUL | Ocular Therapeutix Inc | $2.18B | +640.48% |
| PVLA | Palvella Therapeutics Inc | $2.18B | +638.79% |
| AUPH | Aurinia Pharmaceuticals Inc | $2.11B | +615.07% |
| SNDX | Syndax Pharmaceuticals Inc | $2.08B | +607.31% |
| IOVA | Iovance Biotherapeutics Inc | $2.08B | +605.30% |
| ABCL | AbCellera Biologics Inc | $2.05B | +595.78% |
| NUVB | Nuvation Bio Inc - Class A | $2.04B | +594.34% |
| HRMY | Harmony Biosciences Holdings Inc | $2.02B | +585.92% |
| ADMA | Adma Biologics Inc | $2.02B | +584.80% |
| SION | Sionna Therapeutics Inc | $2.00B | +579.43% |
| GLUE | Monte Rosa Therapeutics Inc | $1.97B | +570.43% |
| ATAI | ATAI Life Sciences N.V. | $1.96B | +565.49% |
| VRDN | Viridian Therapeutics Inc | $1.95B | +563.26% |
| URGN | UroGen Pharma Ltd | $1.94B | +558.41% |
| TYRA | Tyra Biosciences Inc | $1.93B | +554.01% |
| NBTX | Nanobiotix | $1.91B | +549.00% |
| RAPP | Rapport Therapeutics Inc | $1.91B | +548.35% |
| GLPG | Galapagos NV | $1.90B | +544.72% |
| AAPG | Ascentage Pharma Group International | $1.87B | +534.69% |
| STOK | Stoke Therapeutics Inc | $1.86B | +532.27% |
| SRPT | Sarepta Therapeutics Inc | $1.86B | +531.42% |
| BCAX | Bicara Therapeutics Inc | $1.84B | +525.90% |
| ZBIO | Zenas Biopharma Inc | $1.83B | +523.13% |
| PGEN | Precigen Inc | $1.82B | +518.89% |
| ZYME | Zymeworks BC Inc | $1.80B | +512.27% |
| TSHA | Taysha Gene Therapies Inc | $1.78B | +503.96% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.76B | +496.53% |
| FTRE | Fortrea Holdings Inc | $1.69B | +475.44% |
| NKTR | Nektar Therapeutics | $1.69B | +473.81% |
| MPLT | MapLight Therapeutics Inc | $1.69B | +473.19% |
| GHRS | GH Research PLC | $1.67B | +467.18% |
| ANAB | AnaptysBio Inc | $1.62B | +450.38% |
| INVA | Innoviva Inc | $1.62B | +448.74% |
| NTLA | Intellia Therapeutics Inc | $1.57B | +433.44% |
| RAPT | RAPT Therapeutics Inc | $1.56B | +431.33% |
| VIR | Vir Biotechnology Inc | $1.55B | +426.25% |
| SEPN | Septerna Inc | $1.53B | +419.75% |
| AVBP | ArriVent BioPharma Inc | $1.49B | +407.05% |
| ABSI | Absci Corp | $1.49B | +407.05% |
| MAZE | Maze Therapeutics Inc | $1.46B | +396.48% |
| MLTX | MoonLake Immunotherapeutics - Class A | $1.42B | +383.17% |
| NVAX | Novavax Inc | $1.39B | +370.76% |
| KALV | KalVista Pharmaceuticals Inc | $1.38B | +369.86% |
| INBX | Inhibrx Biosciences Inc | $1.33B | +352.56% |
| ARDX | Ardelyx Inc | $1.31B | +344.57% |
| MNKD | Mannkind Corp | $1.26B | +329.11% |
| ANNX | Annexon Inc | $1.26B | +328.72% |
| CRVS | Corvus Pharmaceuticals Inc | $1.25B | +326.12% |
| TRML | Tourmaline Bio Inc | $1.24B | +319.70% |
| SVRA | Savara Inc | $1.19B | +304.37% |
| CAPR | Capricor Therapeutics Inc | $1.17B | +298.55% |
| EYPT | EyePoint Pharmaceuticals Inc | $1.16B | +292.56% |
| ORIC | ORIC Pharmaceuticals Inc | $1.15B | +291.55% |
| WVE | Wave Life Sciences Ltd | $1.14B | +286.07% |
| XNCR | Xencor Inc | $1.11B | +276.82% |
| DRTS | Alpha Tau Medical Ltd | $1.10B | +272.45% |
| CGEM | Cullinan Oncology Inc | $1.10B | +272.13% |
| JBIO | Jade Biosciences Inc | $1.08B | +266.37% |
| CVAC | CureVac N.V. | $1.05B | +256.38% |
| OLMA | Olema Pharmaceuticals Inc | $1.03B | +250.60% |
| MGTX | MeiraGTx Holdings plc | $1.02B | +247.44% |
| KURA | Kura Oncology Inc | $1.01B | +241.57% |
| VTYX | Ventyx Biosciences Inc | $998.72M | +239.20% |
| GRCL | Gracell Biotechnologies Inc | $989.87M | +236.19% |
| VOR | Vor Biopharma Inc | $979.68M | +232.73% |
| JANX | Janux Therapeutics Inc | $975.67M | +231.37% |
| ANRO | Alto Neuroscience Inc | $973.06M | +230.49% |
| SANA | Sana Biotechnology Inc | $957.85M | +225.32% |
| GERN | Geron Corp | $950.51M | +222.83% |
| SLDB | Solid Biosciences Inc | $946.56M | +221.48% |
| PHAR | Pharming Group N.V. | $939.88M | +219.22% |
| LXRX | Lexicon Pharmaceuticals Inc | $936.56M | +218.09% |
| DBVT | DBV Technologies | $930.17M | +215.92% |
| LBRX | LB Pharmaceuticals Inc | $922.18M | +213.21% |
| ABUS | Arbutus Biopharma Corp | $898.08M | +205.02% |
| PHAT | Phathom Pharmaceuticals Inc | $877.84M | +198.15% |
| TBPH | Theravance Biopharma Inc | $872.15M | +196.21% |
| DSGN | Design Therapeutics Inc | $844.21M | +186.72% |
| REPL | Replimune Group Inc | $800.70M | +171.95% |
| ACRS | Aclaris Therapeutics Inc | $782.06M | +165.61% |
| OCS | Oculis Holding AG | $772.84M | +162.48% |
| ZVRA | Zevra Therapeutics Inc | $766.13M | +160.20% |
| CMRX | Chimerix Inc | $766.03M | +160.17% |
| RIGL | Rigel Pharmaceuticals | $758.21M | +157.51% |
| SPRY | ARS Pharmaceuticals Inc | $749.72M | +154.63% |
| OMER | Omeros Corporation | $746.63M | +153.58% |
| MNPR | Monopar Therapeutics Inc | $728.12M | +147.30% |
| DRUG | Bright Minds Biosciences Inc | $728.06M | +147.28% |
| ATXS | Astria Therapeutics Inc | $709.95M | +141.12% |
| CADL | Candel Therapeutics Inc | $706.21M | +139.85% |
| XOMA | XOMA Royalty Corp | $699.64M | +137.62% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $673.55M | +128.76% |
| CLYM | Eliem Therapeutics Inc | $662.55M | +125.03% |
| CRMD | CorMedix Inc | $660.09M | +124.19% |
| IVA | Inventiva | $655.21M | +122.53% |
| CTMX | CytomX Therapeutics Inc | $652.36M | +121.57% |
| RLMD | Relmada Therapeutics Inc | $651.37M | +121.23% |
| MDXG | Mimedx Group Inc | $635.94M | +115.99% |
| RGNX | Regenxbio Inc | $633.34M | +115.11% |
| PRME | Prime Medicine Inc | $630.35M | +114.09% |
| NGNE | Neoleukin Therapeutics Inc | $616.04M | +109.23% |
| TECX | AvroBio Inc | $611.99M | +107.85% |
| FDMT | 4D Molecular Therapeutics Inc | $610.53M | +107.36% |
| GYRE | Gyre Therapeutics Inc | $599.17M | +103.50% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $555.56M | +88.69% |
| CTNM | Contineum Therapeutics Inc - Class A | $546.27M | +85.53% |
| ARVN | Arvinas Inc | $534.06M | +81.39% |
| NVCT | Nuvectis Pharma Inc | $519.64M | +76.49% |
| STTK | Shattuck Labs Inc | $511.69M | +73.79% |
| ZURA | Zura Bio Ltd - Class A | $511.41M | +73.69% |
| VSTM | Verastem Inc | $503.34M | +70.95% |
| SLN | Silence Therapeutics Plc | $493.60M | +67.64% |
| OCGN | Ocugen Inc | $483.80M | +64.31% |
| KYTX | Kyverna Therapeutics Inc | $470.94M | +59.95% |
| ALLO | Allogene Therapeutics Inc | $465.15M | +57.98% |
| SVA | Sinovac Biotech Ltd | $464.94M | +57.91% |
| CABA | Cabaletta Bio Inc | $463.15M | +57.30% |
| RZLT | Rezolute Inc | $456.43M | +55.02% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $451.41M | +53.32% |
| EVMN | Evommune Inc | $447.71M | +52.06% |
| PRTA | Prothena Corporation plc | $447.44M | +51.97% |
| BNTC | Benitec Biopharma Inc | $447.29M | +51.92% |
| VALN | Valneva SE | $440.98M | +49.77% |
| CBIO | N/A | $432.05M | +46.74% |
| STRO | Sutro Biopharma Inc | $430.74M | +46.29% |
| AURA | Aura Biosciences Inc | $430.49M | +46.21% |
| PBYI | Puma Biotechnology Inc | $427.89M | +45.33% |
| ASMB | Assembly Biosciences Inc | $424.80M | +44.28% |
| OVID | Ovid Therapeutics Inc | $416.49M | +41.46% |
| ABEO | Abeona Therapeutics Inc | $414.56M | +40.80% |
| DMAC | DiaMedica Therapeutics Inc | $411.67M | +39.82% |
| CYBN | Cybin Inc | $408.43M | +38.72% |
| AVTX | Avalo Therapeutics Inc | $403.76M | +37.13% |
| AUTL | Autolus Therapeutics plc | $401.88M | +36.49% |
| RCKT | Rocket Pharmaceuticals Inc | $398.30M | +35.28% |
| LRMR | Larimar Therapeutics Inc | $395.79M | +34.43% |
| UPB | Upstream Bio Inc | $395.63M | +34.37% |
| CCCC | C4 Therapeutics Inc | $395.34M | +34.27% |
| IPSC | Century Therapeutics Inc | $390.82M | +32.74% |
| YMAB | Y-Mabs Therapeutics Inc | $390.19M | +32.52% |
| AVIR | Atea Pharmaceuticals Inc | $388.93M | +32.10% |
| CMPX | Compass Therapeutics Inc | $385.39M | +30.89% |
| ENTA | Enanta Pharmaceuticals Inc | $384.48M | +30.58% |
| RVNC | Revance Therapeutics Inc | $380.38M | +29.19% |
| PRTC | PureTech Health plc American Depositary Shares | $376.98M | +28.04% |
| ALT | Altimmune Inc | $373.67M | +26.91% |
| TENX | Tenax Therapeutics Inc | $372.39M | +26.48% |
| PRLD | Prelude Therapeutics Inc | $368.04M | +25.00% |
| XFOR | X4 Pharmaceuticals Inc | $367.85M | +24.93% |
| FENC | Fennec Pharmaceuticals Inc | $366.13M | +24.35% |
| VNDA | Vanda Pharmaceuticals Inc | $351.79M | +19.48% |
| LXEO | Lexeo Therapeutics Inc | $351.17M | +19.27% |
| EDIT | Editas Medicine Inc | $349.39M | +18.66% |
| FATE | Fate Therapeutics Inc | $347.65M | +18.08% |
| FBRX | Forte Biosciences Inc | $340.15M | +15.53% |
| ZNTL | Zentalis Pharmaceuticals Inc | $340.13M | +15.52% |
| PALI | Palisade Bio Inc | $339.87M | +15.43% |
| EPRX | Eupraxia Pharmaceuticals Inc | $338.64M | +15.02% |
| LYEL | Lyell Immunopharma Inc | $332.66M | +12.98% |
| FHTX | Foghorn Therapeutics Inc | $319.97M | +8.67% |
| INDP | Indaptus Therapeutics Inc | $319.34M | +8.46% |
| ANL | Adlai Nortye Ltd | $317.46M | +7.82% |
| GALT | Galectin Therapeutics Inc | $313.48M | +6.47% |
| LCTX | Lineage Cell Therapeutics Inc | $305.39M | +3.72% |
| VTVT | vTv Therapeutics Inc - Class A | $305.06M | +3.61% |
| ELDN | Eledon Pharmaceuticals Inc | $304.92M | +3.56% |
| SCPH | scPharmaceuticals Inc | $304.59M | +3.45% |
| ARTV | Artiva Biotherapeutics Inc | $302.86M | +2.86% |
| OABI | OmniAb Inc | $301.15M | +2.28% |
| BCYC | Bicycle Therapeutics Plc | $294.16M | -0.09% |
| NMRA | Neumora Therapeutics Inc | $293.19M | -0.42% |
| GLSI | Greenwich LifeSciences Inc | $286.57M | -2.67% |
| TTRX | Turn Therapeutics Inc | $285.37M | -3.08% |
| CLLS | Cellectis | $282.48M | -4.06% |
| TRDA | Entrada Therapeutics Inc | $276.01M | -6.26% |
| NAGE | Niagen Bioscience Inc | $275.72M | -6.36% |
| MGNX | Macrogenics Inc | $274.58M | -6.74% |
| SABS | SAB Biotherapeutics Inc | $274.20M | -6.87% |
| ALXO | Alx Oncology Holdings Inc | $273.12M | -7.24% |
| SRZN | Surrozen Inc | $250.37M | -14.97% |
| IRD | Ocuphire Pharma Inc | $248.48M | -15.61% |
| RNAC | Cartesian Therapeutics Inc | $247.77M | -15.85% |
| THRD | Third Harmonic Bio Inc | $241.86M | -17.85% |
| FULC | Fulcrum Therapeutics Inc | $237.12M | -19.46% |
| GNFT | GENFIT S.A. American Depositary Shares | $233.01M | -20.86% |
| ACIU | AC Immune SA | $232.87M | -20.91% |
| AVXL | Anavex Life Sciences Corporation | $231.68M | -21.31% |
| IVVD | Invivyd Inc | $231.05M | -21.53% |
| QTTB | Q32 Bio Inc | $229.68M | -21.99% |
| SLRN | Acelyrin Inc | $228.54M | -22.38% |
| DTIL | Precision Biosciences Inc | $227.35M | -22.78% |
| TARA | Protara Therapeutics Inc | $226.83M | -22.96% |
| CGEN | Compugen Ltd | $223.15M | -24.21% |
| CHRS | Coherus Biosciences Inc | $222.07M | -24.58% |
| NAUT | Nautilus Biotechnology Inc | $221.10M | -24.91% |
| CAMP | CAMP4 Therapeutics Corp | $218.61M | -25.75% |
| KROS | Keros Therapeutics Inc | $217.65M | -26.08% |
| ADAG | Adagene Inc | $217.38M | -26.17% |
| SLGL | Sol-Gel Technologies Ltd | $215.10M | -26.94% |
| KPTI | Karyopharm Therapeutics Inc | $214.84M | -27.03% |
| OBIO | Orchestra BioMed Holdings Inc | $214.00M | -27.32% |
| RNA | Atrium Therapeutics Inc | $210.40M | -28.54% |
| IMUX | Immunic Inc | $205.68M | -30.14% |
| TLSA | Tiziana Life Sciences Ltd | $201.81M | -31.46% |
| CDXS | Codexis Inc | $200.88M | -31.78% |
| NKTX | Nkarta Inc | $197.53M | -32.91% |
| AGEN | Agenus Inc | $192.99M | -34.45% |
| VYGR | Voyager Therapeutics Inc | $192.99M | -34.45% |
| NERV | Minerva Neurosciences Inc | $189.40M | -35.67% |
| KRRO | Korro Bio Inc | $187.93M | -36.17% |
| PRQR | ProQR Therapeutics N.V | $186.49M | -36.66% |
| PLX | Protalix BioTherapeutics Inc | $186.05M | -36.81% |
| TNYA | Tenaya Therapeutics Inc | $182.97M | -37.86% |
| MDWD | MediWound Ltd | $182.55M | -38.00% |
| IFRX | InflaRx N.V. | $182.18M | -38.13% |
| WHWK | Whitehawk Therapeutics Inc | $181.71M | -38.29% |
| ARCT | Arcturus Therapeutics Holdings Inc | $181.62M | -38.31% |
| SGMT | Sagimet Biosciences Inc - Class A | $180.81M | -38.59% |
| ACOG | Alpha Cognition Inc | $180.73M | -38.62% |
| MENS | Jyong Biotech Ltd | $174.10M | -40.87% |
| ACHV | Achieve Life Sciences Inc | $173.54M | -41.06% |
| PEPG | PepGen Inc | $168.86M | -42.65% |
| ANTX | AN2 Therapeutics Inc | $168.05M | -42.92% |
| CRBU | Caribou Biosciences Inc | $167.73M | -43.03% |
| THTX | Theratechnologies Inc | $167.34M | -43.17% |
| ALEC | Alector Inc | $166.54M | -43.44% |
| ORMP | Oramed Pharmaceuticals Inc | $166.16M | -43.57% |
| EQ | Equillium Inc | $165.65M | -43.74% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $164.92M | -43.99% |
| IPHA | Innate Pharma | $164.54M | -44.12% |
| OTLK | Outlook Therapeutics Inc | $163.20M | -44.57% |
| YDES | YD Bio Ltd | $160.69M | -45.42% |
| ABOS | Acumen Pharmaceuticals Inc | $160.35M | -45.54% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $159.83M | -45.72% |
| LENZ | LENZ Therapeutics Inc | $156.46M | -46.86% |
| PYXS | Pyxis Oncology Inc | $152.68M | -48.14% |
| CNTB | Connect Biopharma Holdings Ltd | $152.39M | -48.24% |
| HUMA | Humacyte Inc | $151.33M | -48.60% |
| MIST | Milestone Pharmaceuticals Inc | $149.60M | -49.19% |
| NBP | NovaBridge Biosciences. | $149.30M | -49.29% |
| NRXP | NRX Pharmaceuticals Inc | $149.28M | -49.30% |
| AKTX | Akari Therapeutics Plc | $148.12M | -49.69% |
| MOLN | Molecular Partners AG | $146.63M | -50.20% |
| ARMP | Armata Pharmaceuticals Inc | $146.49M | -50.25% |
| AARD | Aardvark Therapeutics Inc | $145.52M | -50.58% |
| MRSN | Mersana Therapeutics Inc | $145.36M | -50.63% |
| HURA | TuHURA Biosciences Inc | $144.96M | -50.77% |
| GUTS | Fractyl Health Inc | $144.37M | -50.97% |
| PROK | ProKidney Corp - Class A | $137.85M | -53.18% |
| TCRX | Tscan Therapeutics Inc | $137.63M | -53.26% |
| CBUS | Cibus Global Ltd. Class A | $135.62M | -53.94% |
| THAR | Tharimmune Inc | $135.41M | -54.01% |
| SEER | Seer Inc - Class A | $132.16M | -55.11% |
| GNLX | Genelux Corp | $130.49M | -55.68% |
| VXRT | Vaxart Inc | $127.95M | -56.54% |
| ENGN | enGene Holdings Inc | $127.28M | -56.77% |
| UNCY | Unicycive Therapeutics Inc | $126.69M | -56.97% |
| PMN | ProMIS Neurosciences Inc | $125.59M | -57.34% |
| FBIO | Fortress Biotech Inc | $123.12M | -58.18% |
| RANI | Rani Therapeutics Holdings Inc Class A | $121.86M | -58.61% |
| VANI | Vivani Medical Inc | $119.35M | -59.46% |
| ANIX | Anixa Biosciences Inc | $118.73M | -59.68% |
| ALDX | Aldeyra Therapeutics Inc | $115.82M | -60.66% |
| SAVA | Cassava Sciences Inc. | $114.97M | -60.95% |
| RPTX | Repare Therapeutics Inc | $113.91M | -61.31% |
| COYA | Coya Therapeutics Inc | $113.53M | -61.44% |
| KLRS | Kalaris Therapeutics Inc | $110.82M | -62.36% |
| ONCY | Oncolytics Biotech Inc | $104.98M | -64.35% |
| HLVX | HilleVax Inc | $104.74M | -64.43% |
| BDTX | Black Diamond Therapeutics Inc | $103.72M | -64.77% |
| ADVM | Adverum Biotechnologies Inc | $102.40M | -65.22% |
| SPRO | Spero Therapeutics Inc | $98.42M | -66.57% |
| KZIA | Kazia Therapeutics Ltd | $97.74M | -66.80% |
| VRCA | Verrica Pharmaceuticals Inc | $97.23M | -66.98% |
| ICCC | Immucell Corp | $97.07M | -67.03% |
| PYPD | Polypid Ltd | $94.84M | -67.79% |
| BMEA | Biomea Fusion Inc | $93.27M | -68.32% |
| CUE | Cue Biopharma Inc | $92.75M | -68.50% |
| ENLV | Enlivex Ltd | $92.47M | -68.59% |
| PTHS | Channel Therapeutics Corporation | $91.66M | -68.87% |
| MAIA | MAIA Biotechnology Inc | $89.19M | -69.71% |
| NTHI | NeOnc Technologies Holdings Inc | $87.88M | -70.15% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $86.99M | -70.45% |
| CRDF | Cardiff Oncology Inc | $85.46M | -70.97% |
| RLYB | Rallybio Corp | $85.33M | -71.02% |
| CGTX | Cognition Therapeutics Inc | $84.81M | -71.20% |
| LPTX | Leap Therapeutics Inc | $84.76M | -71.21% |
| ATHE | Alterity Therapeutics Ltd | $84.66M | -71.25% |
| ACET | Adicet Bio Inc | $83.31M | -71.71% |
| HRTX | Heron Therapeutics Inc | $83.25M | -71.72% |
| ENTX | Entera Bio Ltd | $82.99M | -71.81% |
| INO | Inovio Pharmaceuticals Inc | $81.63M | -72.27% |
| CSBR | Champions Oncology Inc | $80.27M | -72.74% |
| NRXS | Neuraxis Inc | $79.92M | -72.86% |
| FBIOP | Fortress Biotech Inc | $77.72M | -73.60% |
| ATHA | Athira Pharma Inc | $77.21M | -73.78% |
| PMVP | PMV Pharmaceuticals Inc | $74.66M | -74.64% |
| GLTO | Galecto Inc | $74.66M | -74.64% |
| ACRV | Acrivon Therapeutics Inc | $74.39M | -74.73% |
| ATRA | Atara Biotherapeutics Inc | $72.78M | -75.28% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $71.93M | -75.57% |
| GANX | Gain Therapeutics Inc | $71.38M | -75.76% |
| XBIT | XBiotech Inc | $69.82M | -76.29% |
| PLRX | Pliant Therapeutics Inc | $69.34M | -76.45% |
| HYFT | MindWalk Holdings Corp | $69.31M | -76.46% |
| MNOV | Medicinova Inc | $68.91M | -76.60% |
| SPRB | Spruce Biosciences Inc | $67.96M | -76.92% |
| ELTX | Elicio Therapeutics Inc | $65.05M | -77.91% |
| KLTO | Klotho Neurosciences Inc Com | $63.55M | -78.42% |
| ACHL | Achilles Therapeutics Plc | $63.22M | -78.53% |
| EDSA | Edesa Biotech Inc | $61.04M | -79.27% |
| OSTX | OS Therapies Inc | $60.88M | -79.32% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $59.20M | -79.89% |
| IBIO | iBio Inc | $58.38M | -80.17% |
| CNTX | Context Therapeutics Inc | $57.91M | -80.33% |
| OKYO | OKYO Pharma Ltd - New | $56.13M | -80.94% |
| BOLD | Boundless Bio Inc | $55.35M | -81.20% |
| INMB | INmune Bio Inc | $55.03M | -81.31% |
| CING | Cingulate Inc | $54.66M | -81.44% |
| KZR | Kezar Life Sciences Inc | $53.76M | -81.74% |
| INKT | MiNK Therapeutics Inc | $53.21M | -81.93% |
| XLO | Xilio Therapeutics Inc | $52.74M | -82.09% |
| MREO | Mereo Biopharma Group Plc | $52.58M | -82.14% |
| ATYR | Atyr Pharma Inc | $52.39M | -82.21% |
| MCRB | Seres Therapeutics Inc | $52.28M | -82.24% |
| BYSI | BeyondSpring Inc | $52.22M | -82.26% |
| EXOZ | Invizyne Technologies Inc | $51.89M | -82.38% |
| RNTX | Rein Therapeutics Inc | $51.79M | -82.41% |
| TIL | Instil Bio Inc | $51.68M | -82.45% |
| ANVS | Annovis Bio Inc | $51.65M | -82.46% |
| GOSS | Gossamer Bio Inc | $51.14M | -82.63% |
| IBO | Impact BioMedical Inc | $50.13M | -82.98% |
| MGX | Metagenomi Inc | $48.56M | -83.51% |
| DWTX | Virios Therapeutics Inc | $48.10M | -83.66% |
| LVTX | LAVA Therapeutics NV | $45.77M | -84.45% |
| TELO | Telomir Pharmaceuticals Inc | $45.73M | -84.47% |
| DYAI | Dyadic International Inc DE | $44.46M | -84.90% |
| PDSB | PDS Biotechnology Corporation | $41.64M | -85.86% |
| APLM | Apollomics Inc - Class A | $41.33M | -85.96% |
| ACTU | Actuate Therapeutics Inc | $40.78M | -86.15% |
| FGEN | FibroGen Inc | $39.31M | -86.65% |
| GRCE | Acasti Pharma Inc | $38.94M | -86.78% |
| VERU | Veru Inc | $38.84M | -86.81% |
| RNXT | RenovoRx Inc | $38.73M | -86.85% |
| NNVC | NanoViricides Inc | $37.23M | -87.35% |
| NTRB | Nutriband Inc | $37.08M | -87.41% |
| RADX | Radiopharm Theranostics Ltd | $36.10M | -87.74% |
| GBIO | Generation Bio Company | $35.97M | -87.78% |
| GNTA | Genenta Science SpA | $35.85M | -87.82% |
| ALGS | Aligos Therapeutics Inc | $35.71M | -87.87% |
| MURA | Mural Oncology plc | $35.34M | -88.00% |
| LTRN | Lantern Pharma Inc | $34.89M | -88.15% |
| LITS | Lite Strategy Inc | $34.77M | -88.19% |
| HYPD | Eyenovia Inc | $34.51M | -88.28% |
| LSTA | Lisata Therapeutics Inc | $34.15M | -88.40% |
| ABVC | ABVC BioPharma Inc | $32.98M | -88.80% |
| ESLA | Estrella Immunopharma Inc | $32.50M | -88.96% |
| SNTI | Senti Biosciences Inc | $32.39M | -89.00% |
| DARE | Dare Bioscience Inc | $30.14M | -89.76% |
| SER | AgeX Therapeutics Inc | $29.05M | -90.13% |
| SGMO | Sangamo Therapeutics Inc | $28.83M | -90.21% |
| BCTX | BriaCell Therapeutics Corp - New | $28.57M | -90.30% |
| ATNM | Actinium Pharmaceuticals Inc | $28.56M | -90.30% |
| CRVO | CervoMed Inc | $28.42M | -90.35% |
| PSTV | Plus Therapeutics Inc | $28.00M | -90.49% |
| TVRD | Cara Therapeutics Inc | $27.49M | -90.66% |
| BRNS | Barinthus Biotherapeutics Plc. | $26.44M | -91.02% |
| IGC | IGC Pharma Inc | $26.36M | -91.05% |
| EVAX | Evaxion Biotech A/S | $25.44M | -91.36% |
| VYNE | VYNE Therapeutics Inc | $25.25M | -91.42% |
| GRDX | Entero Therapeutics Inc | $24.74M | -91.60% |
| NXTC | Nextcure Inc | $23.92M | -91.88% |
| MRKR | Marker Therapeutics Inc | $23.55M | -92.00% |
| NRSN | NeuroSense Therapeutics Ltd | $23.41M | -92.05% |
| CELU | Celularity Inc - Class A | $22.49M | -92.36% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $21.96M | -92.54% |
| OPT | Opthea Ltd | $21.53M | -92.69% |
| SKYE | Skye Bioscience Inc | $21.29M | -92.77% |
| PLRZ | Polyrizon Ltd | $21.02M | -92.86% |
| ATOS | Atossa Therapeutics Inc | $21.01M | -92.86% |
| PHXM | PHAXIAM Therapeutics SA ADR | $20.38M | -93.08% |
| TVGN | Tevogen Bio Holdings Inc | $19.93M | -93.23% |
| SNSE | Sensei Biotherapeutics Inc | $19.48M | -93.39% |
| JSPR | Jasper Therapeutics Inc | $19.37M | -93.42% |
| KALA | Kala Bio Inc | $19.15M | -93.50% |
| NEUP | Neuphoria Therapeutics Inc | $18.93M | -93.57% |
| NCEL | NLS Pharmaceutics Ltd | $18.85M | -93.60% |
| ALLR | Allarity Therapeutics Inc | $18.67M | -93.66% |
| ICU | SeaStar Medical Holding Corp | $18.45M | -93.73% |
| PLUR | Pluri Inc | $18.25M | -93.80% |
| LPCN | Lipocine Inc | $17.64M | -94.01% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $17.55M | -94.04% |
| HOWL | Werewolf Therapeutics Inc | $16.50M | -94.40% |
| HIND | ReShape Lifesciences Inc | $15.93M | -94.59% |
| PTN | Palatin Technologies Inc | $15.81M | -94.63% |
| PASG | Passage Bio Inc | $15.75M | -94.65% |
| LGVN | Longeveron Inc - Class A | $15.75M | -94.65% |
| CYCN | Cyclerion Therapeutics Inc | $15.74M | -94.66% |
| TPST | Tempest Therapeutics Inc | $15.35M | -94.79% |
| CLRB | Cellectar Biosciences Inc | $14.97M | -94.92% |
| APLT | Applied Therapeutics Inc | $14.86M | -94.95% |
| HOTH | Hoth Therapeutics Inc | $14.64M | -95.03% |
| LEXX | Lexaria Bioscience Corp | $14.58M | -95.05% |
| IOBT | IO Biotech Inc | $14.50M | -95.08% |
| HOOK | Hookipa Pharma Inc | $14.43M | -95.10% |
| INAB | IN8bio Inc | $14.18M | -95.18% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $14.00M | -95.25% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $13.82M | -95.31% |
| BIVI | BioVie Inc - Class A | $13.35M | -95.47% |
| BLRX | Bioline Rx Ltd | $13.35M | -95.47% |
| LNAI | Lunai Bioworks Inc | $13.33M | -95.47% |
| COCP | Cocrystal Pharma Inc | $13.24M | -95.50% |
| QNCX | Quince Therapeutics Inc | $13.03M | -95.57% |
| LSB | LakeShore Biopharma Co Ltd | $13.02M | -95.58% |
| GTBP | GT Biopharma Inc | $12.33M | -95.81% |
| MBRX | Moleculin Biotech Inc | $12.33M | -95.81% |
| CALC | CalciMedica Inc | $12.31M | -95.82% |
| INTS | Intensity Therapeutics Inc | $12.30M | -95.82% |
| AIM | AIM ImmunoTech Inc. | $12.01M | -95.92% |
| KTTA | Pasithea Therapeutics Corp | $11.92M | -95.95% |
| QNRX | Quoin Pharmaceuticals Ltd | $11.92M | -95.95% |
| CTXR | Citius Pharmaceuticals Inc | $11.88M | -95.96% |
| GDTC | CytoMed Therapeutics Ltd | $11.32M | -96.16% |
| TOVX | Theriva Biologics Inc | $11.15M | -96.21% |
| CMMB | Chemomab Therapeutics Ltd | $10.93M | -96.29% |
| BCLI | Brainstorm Cell Therapeutics Inc | $10.73M | -96.35% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $10.43M | -96.46% |
| PHIO | Phio Pharmaceuticals Corp | $10.34M | -96.49% |
| XCUR | Exicure Inc | $10.33M | -96.49% |
| CVM | Cel-Sci Corp | $10.15M | -96.55% |
| MLEC | Moolec Science SA | $10.06M | -96.58% |
| KPRX | Kiora Pharmaceuticals Inc | $9.90M | -96.64% |
| BCDA | BioCardia Inc | $9.59M | -96.74% |
| MTVA | MetaVia Inc | $9.55M | -96.76% |
| VTGN | VistaGen Therapeutics Inc | $9.48M | -96.78% |
| CRIS | Curis Inc | $9.45M | -96.79% |
| TRAW | Traws Pharma Inc | $9.16M | -96.89% |
| ASBP | Aspire Biopharma Holdings Inc | $9.03M | -96.93% |
| EPIX | Essa Pharma Inc | $8.93M | -96.97% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $8.92M | -96.97% |
| IMNN | Imunon Inc | $8.71M | -97.04% |
| BRTX | BioRestorative Therapies Inc | $8.66M | -97.06% |
| APRE | Aprea Therapeutics Inc | $8.48M | -97.12% |
| ADXN | Addex Therapeutics Ltd | $8.21M | -97.21% |
| SYBX | Synlogic Inc | $8.20M | -97.21% |
| IMRN | Immuron Ltd | $8.15M | -97.23% |
| BOLT | Bolt Biotherapeutics Inc | $8.09M | -97.25% |
| ITRM | Iterum Therapeutics Plc | $8.06M | -97.26% |
| RNAZ | TransCode Therapeutics Inc | $7.97M | -97.29% |
| ERNA | Ernexa Therapeutics Inc | $7.85M | -97.33% |
| PMCB | PharmaCyte Biotech Inc | $7.57M | -97.43% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $7.49M | -97.46% |
| XTLB | X.T.L. Biopharmaceuticals Ltd | $7.34M | -97.51% |
| AEON | AEON Biopharma Inc - Class A | $7.31M | -97.52% |
| BCAB | BioAtla Inc | $7.07M | -97.60% |
| CANF | Can-Fite Biopharma Ltd | $6.87M | -97.67% |
| KAPA | Kairos Pharma Ltd | $6.75M | -97.71% |
| XBIO | Xenetic Biosciences Inc | $6.65M | -97.74% |
| JUNS | Jupiter Neurosciences Inc | $6.48M | -97.80% |
| PCSA | Processa Pharmaceuticals Inc | $6.40M | -97.83% |
| GOVX | Geovax Labs Inc | $6.29M | -97.87% |
| CURX | Curanex Pharmaceuticals Inc | $6.11M | -97.93% |
| PPBT | Purple Biotech Ltd | $6.05M | -97.95% |
| HCWB | HCW Biologics Inc | $6.02M | -97.95% |
| APM | Aptorum Group Limited Class A Ordinary Shares | $6.01M | -97.96% |
| ACXP | Acurx Pharmaceuticals Inc | $5.93M | -97.99% |
| CVKD | Cadrenal Therapeutics Inc | $5.89M | -98.00% |
| PULM | Pulmatrix Inc | $5.73M | -98.05% |
| EVGN | Evogene Ltd | $5.64M | -98.08% |
| APVO | Aptevo Therapeutics Inc | $5.50M | -98.13% |
| CDIO | Cardio Diagnostics Holdings Inc | $5.30M | -98.20% |
| SILO | SILO Pharma Inc | $5.29M | -98.20% |
| DRMA | Dermata Therapeutics Inc | $5.23M | -98.22% |
| LIMN | Liminatus Pharma Inc | $5.14M | -98.25% |
| TCRT | Alaunos Therapeutics Inc | $5.07M | -98.28% |
| BGMS | Bio Green Med Solution Inc | $5.00M | -98.30% |
| NCNA | NuCana plc | $4.99M | -98.30% |
| TTNP | Titan Pharmaceuticals Inc (de) | $4.91M | -98.33% |
| CLGN | CollPlant Biotechnologies Ltd New | $4.80M | -98.37% |
| ALZN | Alzamend Neuro Inc | $4.68M | -98.41% |
| GNPX | Genprex Inc | $4.44M | -98.49% |
| CASI | CASI Pharmaceuticals Inc | $4.27M | -98.55% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $4.26M | -98.55% |
| REVB | Revelation Biosciences Inc | $4.26M | -98.55% |
| MBIO | Mustang Bio Inc | $4.25M | -98.56% |
| ADIL | Adial Pharmaceuticals Inc | $4.24M | -98.56% |
| ENVB | Enveric Biosciences Inc | $4.15M | -98.59% |
| CNSP | Cns Pharmaceuticals Inc | $4.14M | -98.59% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $4.09M | -98.61% |
| SNGX | Soligenix Inc | $3.91M | -98.67% |
| PBM | Psyence Biomedical Ltd | $3.76M | -98.72% |
| CELZ | Creative Medical Technology Holdings Inc | $3.70M | -98.74% |
| GLMD | Galmed Pharmaceuticals Ltd | $3.38M | -98.85% |
| XRTX | XORTX Therapeutics Inc | $3.34M | -98.86% |
| FBLG | FibroBiologics Inc | $3.18M | -98.92% |
| SLXN | Silexion Therapeutics Corp | $3.11M | -98.94% |
| SPRC | SciSparc Ltd | $3.05M | -98.97% |
| BDRX | Biodexa Pharmaceuticals Plc | $2.98M | -98.99% |
| AFMD | Affimed N.V. | $2.98M | -98.99% |
| ENSC | Ensysce Biosciences Inc | $2.88M | -99.02% |
| ARTL | Artelo Biosciences Inc | $2.75M | -99.07% |
| GRI | GRI Bio Inc | $2.57M | -99.13% |
| ONCO | Onconetix Inc | $2.54M | -99.14% |
| PPCB | Propanc Biopharma Inc | $2.50M | -99.15% |
| VIVS | VivoSim Labs Inc | $2.47M | -99.16% |
| OGEN | Oragenics Inc | $2.45M | -99.17% |
| NBY | Stablecoin Development Corp | $2.40M | -99.18% |
| NTBL | Notable Labs Inc Ord | $2.39M | -99.19% |
| BBLG | Bone Biologics Corp | $2.23M | -99.24% |
| AZTR | Azitra Inc | $2.22M | -99.24% |
| MTNB | Matinas Biopharma Holdings Inc | $2.18M | -99.26% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $2.15M | -99.27% |
| CMND | Clearmind Medicine Inc | $2.12M | -99.28% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $2.09M | -99.29% |
| CLDI | Calidi Biotherapeutics Inc | $1.99M | -99.32% |
| ONCT | Oncternal Therapeutics Inc | $1.56M | -99.47% |
| VRAX | Virax Biolabs Group Ltd - Class A | $1.52M | -99.48% |
| ABP | Abpro Holdings, Inc Common Stock | $1.43M | -99.52% |
| JAGX | Jaguar Health Inc | $1.34M | -99.54% |
| ZVSA | ZyVersa Therapeutics Inc | $1.03M | -99.65% |
| LYRA | Lyra Therapeutics Inc | $927198.36 | -99.69% |
| SCNI | Scinai Immunotherapeutics Ltd | $912143.15 | -99.69% |
| TNFA | TNF Pharmaceuticals Inc | $551031.39 | -99.81% |
| PTIX | Protagenic Therapeutics Inc | $503648.74 | -99.83% |
| SLRX | Decoy Therapeutics Inc | $446853.12 | -99.85% |
| ELAB | PMGC Holdings Inc | $221376.00 | -99.92% |
| CDT | CDT Equity Inc | $110551.31 | -99.96% |
| ADTX | Aditxt Inc | $98471.97 | -99.97% |