| REGN | Regeneron Pharmaceuticals Inc | $40.87B | +731005.55% |
| VRTX | Vertex Pharmaceuticals Inc | $26.48B | +473681.75% |
| BNTX | BioNTech SE | $21.10B | +377289.58% |
| RPRX | Royalty Pharma plc - Class A | $19.82B | +354379.70% |
| GMAB | Genmab | $12.38B | +221291.77% |
| JAZZ | Jazz Pharmaceuticals plc | $11.86B | +212057.42% |
| MRNA | Moderna Inc | $11.49B | +205409.84% |
| ARGX | Argen X SE | $8.68B | +155225.55% |
| BMRN | Biomarin Pharmaceutical Inc | $8.59B | +153585.44% |
| ONC | BeiGene Ltd | $8.55B | +152916.44% |
| SVA | Sinovac Biotech Ltd | $8.54B | +152703.67% |
| INCY | Incyte Corp | $7.34B | +131190.04% |
| ROIV | Roivant Sciences Ltd | $5.71B | +102023.20% |
| ALNY | Alnylam Pharmaceuticals Inc | $4.97B | +88743.13% |
| AAPG | Ascentage Pharma Group International | $3.97B | +70849.93% |
| IONS | Ionis Pharmaceuticals Inc | $3.45B | +61616.80% |
| GLPG | Galapagos NV | $3.41B | +60813.56% |
| PCVX | Vaxcyte Inc | $3.35B | +59798.18% |
| SRPT | Sarepta Therapeutics Inc | $3.18B | +56768.23% |
| PTCT | PTC Therapeutics Inc | $2.87B | +51225.65% |
| CRSP | CRISPR Therapeutics AG | $2.73B | +48662.43% |
| FTRE | Fortrea Holdings Inc | $2.68B | +47903.58% |
| HALO | Halozyme Therapeutics Inc | $2.67B | +47712.50% |
| NBP | NovaBridge Biosciences. | $2.61B | +46643.60% |
| EXEL | Exelixis Inc | $2.59B | +46297.01% |
| TECH | Bio-Techne Corp | $2.55B | +45527.92% |
| ENLV | Enlivex Ltd | $2.33B | +41527.87% |
| ARWR | Arrowhead Pharmaceuticals Inc | $2.27B | +40477.19% |
| RVMD | Revolution Medicines Inc | $2.25B | +40217.30% |
| INSM | Insmed Inc | $2.08B | +37035.30% |
| ASND | Ascendis Pharma A/S | $2.01B | +35774.21% |
| INVA | Innoviva Inc | $1.84B | +32754.87% |
| TLX | Telix Pharmaceuticals Ltd | $1.77B | +31580.04% |
| KYMR | Kymera Therapeutics Inc | $1.67B | +29757.17% |
| ACAD | Acadia Pharmaceuticals Inc | $1.61B | +28616.10% |
| LEGN | Legend Biotech Corp | $1.60B | +28464.39% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $1.53B | +27307.96% |
| TGTX | TG Therapeutics Inc | $1.53B | +27249.50% |
| GPCR | Structure Therapeutics Inc | $1.51B | +26878.96% |
| BEAM | Beam Therapeutics Inc | $1.48B | +26390.13% |
| PRAX | Praxis Precision Medicines Inc | $1.46B | +26021.68% |
| CRNX | Crinetics Pharmaceuticals Inc | $1.40B | +24968.39% |
| KRYS | Krystal Biotech Inc | $1.40B | +24890.47% |
| XENE | Xenon Pharmaceuticals Inc | $1.39B | +24708.77% |
| BBIO | BridgeBio Pharma Inc | $1.37B | +24425.60% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.34B | +23862.83% |
| NUVL | Nuvalent Inc - Class A | $1.33B | +23713.02% |
| ABCL | AbCellera Biologics Inc | $1.31B | +23283.04% |
| RARE | Ultragenyx Pharmaceutical Inc | $1.30B | +23084.26% |
| APGE | Apogee Therapeutics Inc | $1.29B | +23042.29% |
| CYTK | Cytokinetics Inc | $1.27B | +22681.36% |
| HRMY | Harmony Biosciences Holdings Inc | $1.27B | +22651.77% |
| DNLI | Denali Therapeutics Inc | $1.27B | +22548.00% |
| DNTH | Dianthus Therapeutics Inc | $1.25B | +22205.62% |
| MDGL | Madrigal Pharmaceuticals Inc | $1.23B | +21855.76% |
| AGIO | Agios Pharmaceuticals Inc | $1.18B | +21098.39% |
| CAI | Caris Life Sciences Inc - Class A | $1.16B | +20694.06% |
| CPRX | Catalyst Pharmaceuticals Inc | $1.15B | +20429.70% |
| CVAC | CureVac N.V. | $1.14B | +20268.86% |
| CGON | Cg Oncology Inc | $1.14B | +20208.80% |
| ZLAB | Zai Lab Ltd | $1.10B | +19501.74% |
| APLS | Apellis Pharmaceuticals Inc | $1.08B | +19265.51% |
| DYN | Dyne Therapeutics Inc | $1.08B | +19219.32% |
| IMCR | Immunocore Holdings plc | $1.07B | +19078.80% |
| NVAX | Novavax Inc | $1.04B | +18561.22% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $1.03B | +18380.77% |
| IDYA | Ideaya Biosciences Inc | $1.03B | +18331.99% |
| JANX | Janux Therapeutics Inc | $1.03B | +18294.01% |
| VIR | Vir Biotechnology Inc | $1.03B | +18246.78% |
| TERN | Terns Pharmaceuticals Inc | $1.03B | +18237.71% |
| AKRO | Akero Therapeutics Inc | $1.01B | +17888.86% |
| RCUS | Arcus Biosciences Inc | $997.00M | +17735.42% |
| IMVT | Immunovant Inc | $957.01M | +17020.11% |
| FOLD | Amicus Therapeutics Inc | $949.87M | +16892.31% |
| IOVA | Iovance Biotherapeutics Inc | $925.66M | +16459.30% |
| MRUS | Merus N.V | $904.20M | +16075.24% |
| COGT | Cogent Biosciences Inc | $903.01M | +16053.95% |
| MIRM | Mirum Pharmaceuticals Inc | $890.92M | +15837.67% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $849.19M | +15091.25% |
| CRMD | CorMedix Inc | $815.64M | +14491.00% |
| CORT | Corcept Therapeutics Inc | $814.88M | +14477.48% |
| VRDN | Viridian Therapeutics Inc | $789.02M | +14014.79% |
| MESO | Mesoblast Ltd | $782.31M | +13894.76% |
| BLTE | Belite Bio Inc | $780.56M | +13863.43% |
| QURE | uniQure N.V. | $778.71M | +13830.34% |
| SYRE | Spyre Therapeutics Inc | $763.95M | +13566.42% |
| NKTR | Nektar Therapeutics | $763.27M | +13554.22% |
| NTLA | Intellia Therapeutics Inc | $758.78M | +13473.86% |
| IRON | Disc Medicine Inc | $750.21M | +13320.63% |
| ZBIO | Zenas Biopharma Inc | $747.68M | +13275.35% |
| MNKD | Mannkind Corp | $744.40M | +13216.69% |
| XNCR | Xencor Inc | $736.85M | +13081.50% |
| GLUE | Monte Rosa Therapeutics Inc | $736.43M | +13074.03% |
| NAMS | NewAmsterdam Pharma Company NV | $732.64M | +13006.31% |
| OCUL | Ocular Therapeutix Inc | $732.53M | +13004.28% |
| AUPH | Aurinia Pharmaceuticals Inc | $724.00M | +12851.65% |
| AXSM | Axsome Therapeutics Inc | $713.61M | +12665.78% |
| RLAY | Relay Therapeutics Inc | $699.61M | +12415.44% |
| PTGX | Protagonist Therapeutics Inc | $697.46M | +12376.91% |
| ALMS | Alumis Inc | $671.59M | +11914.10% |
| ADMA | Adma Biologics Inc | $665.18M | +11799.53% |
| MLYS | Mineralys Therapeutics Inc | $652.86M | +11579.11% |
| KURA | Kura Oncology Inc | $652.55M | +11573.54% |
| BCYC | Bicycle Therapeutics Plc | $652.40M | +11570.77% |
| SMMT | Summit Therapeutics Inc | $647.86M | +11489.55% |
| ARVN | Arvinas Inc | $647.50M | +11483.18% |
| IBRX | ImmunityBio Inc | $646.64M | +11467.75% |
| CNTA | Centessa Pharmaceuticals plc | $641.76M | +11380.55% |
| VERA | Vera Therapeutics Inc - Class A | $621.74M | +11022.34% |
| IMNM | Immunome Inc | $619.79M | +10987.51% |
| NUVB | Nuvation Bio Inc - Class A | $610.24M | +10816.65% |
| SLNO | Soleno Therapeutics Inc | $608.39M | +10783.51% |
| VKTX | Viking Therapeutics Inc | $608.24M | +10780.89% |
| ACLX | Arcellx Inc | $603.99M | +10704.83% |
| THAR | Tharimmune Inc | $584.65M | +10358.94% |
| WVE | Wave Life Sciences Ltd | $583.54M | +10339.07% |
| TARS | Tarsus Pharmaceuticals Inc | $581.13M | +10295.97% |
| VRNA | Verona Pharma Plc | $572.87M | +10148.14% |
| SEPN | Septerna Inc | $569.69M | +10091.20% |
| TVTX | Travere Therapeutics Inc | $555.19M | +9831.81% |
| BCAX | Bicara Therapeutics Inc | $553.60M | +9803.38% |
| PRTC | PureTech Health plc American Depositary Shares | $553.24M | +9796.99% |
| ABVX | Abivax | $547.14M | +9687.87% |
| IMTX | Immatics N.V | $543.83M | +9628.63% |
| NRIX | Nurix Therapeutics Inc | $535.54M | +9480.32% |
| GLTO | Galecto Inc | $535.44M | +9478.57% |
| SRRK | Scholar Rock Holding Corp | $535.25M | +9475.21% |
| GERN | Geron Corp | $534.12M | +9454.92% |
| OLMA | Olema Pharmaceuticals Inc | $530.64M | +9392.75% |
| AUTL | Autolus Therapeutics plc | $527.07M | +9328.71% |
| CDTX | Cidara Therapeutics Inc | $518.65M | +9178.18% |
| EWTX | Edgewise Therapeutics Inc | $518.52M | +9175.89% |
| FDMT | 4D Molecular Therapeutics Inc | $512.90M | +9075.40% |
| CLDX | Celldex Therapeutics Inc | $511.25M | +9045.87% |
| DAWN | Day One Biopharmaceuticals Inc | $507.83M | +8984.56% |
| VOR | Vor Biopharma Inc | $506.75M | +8965.22% |
| RIGL | Rigel Pharmaceuticals | $504.61M | +8926.98% |
| ARDX | Ardelyx Inc | $504.51M | +8925.17% |
| ORKA | ARCA biopharma Inc | $504.48M | +8924.69% |
| RAPP | Rapport Therapeutics Inc | $497.60M | +8801.56% |
| PHAR | Pharming Group N.V. | $489.37M | +8654.29% |
| VCEL | Vericel Corp | $485.63M | +8587.42% |
| ZYME | Zymeworks BC Inc | $478.21M | +8454.83% |
| SNDX | Syndax Pharmaceuticals Inc | $472.67M | +8355.60% |
| TBPH | Theravance Biopharma Inc | $472.31M | +8349.25% |
| BHVN | Biohaven Ltd | $466.41M | +8243.58% |
| ELVN | Enliven Therapeutics Inc | $464.85M | +8215.78% |
| RVNC | Revance Therapeutics Inc | $461.56M | +8156.96% |
| ERAS | Erasca Inc | $461.23M | +8151.06% |
| ARQT | Arcutis Biotherapeutics Inc | $460.00M | +8129.03% |
| MBX | MBX Biosciences Inc | $452.70M | +7998.41% |
| STOK | Stoke Therapeutics Inc | $443.28M | +7829.82% |
| RYTM | Rhythm Pharmaceuticals Inc | $442.32M | +7812.63% |
| ORIC | ORIC Pharmaceuticals Inc | $436.76M | +7713.27% |
| SLRN | Acelyrin Inc | $436.50M | +7708.66% |
| TNGX | Tango Therapeutics Inc | $435.79M | +7695.92% |
| VNDA | Vanda Pharmaceuticals Inc | $433.52M | +7655.37% |
| SLDB | Solid Biosciences Inc | $422.89M | +7465.17% |
| MAZE | Maze Therapeutics Inc | $419.71M | +7408.23% |
| MPLT | MapLight Therapeutics Inc | $418.79M | +7391.74% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $417.65M | +7371.31% |
| TYRA | Tyra Biosciences Inc | $412.04M | +7271.02% |
| CELC | Celcuity Inc | $410.16M | +7237.46% |
| CGEM | Cullinan Oncology Inc | $402.98M | +7109.02% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $401.29M | +7078.77% |
| MLTX | MoonLake Immunotherapeutics - Class A | $400.37M | +7062.33% |
| ALLO | Allogene Therapeutics Inc | $395.96M | +6983.33% |
| LBRX | LB Pharmaceuticals Inc | $393.48M | +6939.03% |
| SANA | Sana Biotechnology Inc | $373.59M | +6583.24% |
| VALN | Valneva SE | $372.40M | +6561.91% |
| NKTX | Nkarta Inc | $372.07M | +6556.05% |
| CTMX | CytomX Therapeutics Inc | $359.36M | +6328.59% |
| FBIO | Fortress Biotech Inc | $356.87M | +6284.15% |
| PROK | ProKidney Corp - Class A | $351.61M | +6189.95% |
| LYEL | Lyell Immunopharma Inc | $350.63M | +6172.38% |
| PRTA | Prothena Corporation plc | $349.89M | +6159.28% |
| AVBP | ArriVent BioPharma Inc | $349.30M | +6148.57% |
| FULC | Fulcrum Therapeutics Inc | $346.77M | +6103.40% |
| RGNX | Regenxbio Inc | $341.89M | +6016.17% |
| TRDA | Entrada Therapeutics Inc | $335.52M | +5902.11% |
| REPL | Replimune Group Inc | $332.39M | +5846.12% |
| ANAB | AnaptysBio Inc | $329.68M | +5797.75% |
| KALV | KalVista Pharmaceuticals Inc | $328.92M | +5784.03% |
| CCCC | C4 Therapeutics Inc | $328.86M | +5783.02% |
| IPSC | Century Therapeutics Inc | $326.55M | +5741.74% |
| CAPR | Capricor Therapeutics Inc | $326.28M | +5736.91% |
| CBUS | Cibus Global Ltd. Class A | $324.20M | +5699.68% |
| EVMN | Evommune Inc | $322.45M | +5668.43% |
| JBIO | Jade Biosciences Inc | $319.43M | +5614.36% |
| UPB | Upstream Bio Inc | $318.05M | +5589.70% |
| ENTA | Enanta Pharmaceuticals Inc | $314.70M | +5529.77% |
| KROS | Keros Therapeutics Inc | $312.29M | +5486.64% |
| DRUG | Bright Minds Biosciences Inc | $312.15M | +5484.00% |
| MDXG | Mimedx Group Inc | $308.68M | +5421.93% |
| ENGN | enGene Holdings Inc | $307.52M | +5401.32% |
| KOD | Kodiak Sciences Inc | $306.01M | +5374.17% |
| PHAT | Phathom Pharmaceuticals Inc | $305.12M | +5358.32% |
| SION | Sionna Therapeutics Inc | $305.04M | +5356.87% |
| TSHA | Taysha Gene Therapies Inc | $300.35M | +5273.01% |
| PRME | Prime Medicine Inc | $294.73M | +5172.45% |
| OABI | OmniAb Inc | $293.65M | +5153.13% |
| RNA | Atrium Therapeutics Inc | $292.36M | +5130.05% |
| CLLS | Cellectis | $289.19M | +5073.29% |
| RNAC | Cartesian Therapeutics Inc | $288.39M | +5059.05% |
| EYPT | EyePoint Pharmaceuticals Inc | $288.22M | +5055.94% |
| SPRY | ARS Pharmaceuticals Inc | $287.57M | +5044.38% |
| OMER | Omeros Corporation | $286.17M | +5019.37% |
| RCKT | Rocket Pharmaceuticals Inc | $285.41M | +5005.67% |
| FATE | Fate Therapeutics Inc | $284.92M | +4996.89% |
| ALT | Altimmune Inc | $279.93M | +4907.67% |
| THRD | Third Harmonic Bio Inc | $279.84M | +4906.01% |
| ZVRA | Zevra Therapeutics Inc | $278.58M | +4883.52% |
| ABUS | Arbutus Biopharma Corp | $277.16M | +4858.21% |
| ANRO | Alto Neuroscience Inc | $276.26M | +4842.02% |
| GHRS | GH Research PLC | $275.27M | +4824.28% |
| LENZ | LENZ Therapeutics Inc | $272.54M | +4775.40% |
| SEER | Seer Inc - Class A | $272.13M | +4768.19% |
| ATXS | Astria Therapeutics Inc | $271.87M | +4763.43% |
| XOMA | XOMA Royalty Corp | $271.86M | +4763.29% |
| XFOR | X4 Pharmaceuticals Inc | $270.28M | +4735.08% |
| TRML | Tourmaline Bio Inc | $269.30M | +4717.44% |
| ORMP | Oramed Pharmaceuticals Inc | $268.85M | +4709.43% |
| LXRX | Lexicon Pharmaceuticals Inc | $268.82M | +4708.93% |
| AVIR | Atea Pharmaceuticals Inc | $267.08M | +4677.75% |
| DBVT | DBV Technologies | $266.40M | +4665.65% |
| CHRS | Coherus Biosciences Inc | $266.02M | +4658.89% |
| ATAI | ATAI Life Sciences N.V. | $264.88M | +4638.41% |
| PVLA | Palvella Therapeutics Inc | $263.76M | +4618.41% |
| NGNE | Neoleukin Therapeutics Inc | $263.14M | +4607.35% |
| ANNX | Annexon Inc | $262.89M | +4602.83% |
| TCRX | Tscan Therapeutics Inc | $262.23M | +4590.97% |
| CTNM | Contineum Therapeutics Inc - Class A | $261.35M | +4575.30% |
| PHVS | Pharvaris NV | $259.79M | +4547.37% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $257.91M | +4513.81% |
| KYTX | Kyverna Therapeutics Inc | $257.02M | +4497.92% |
| URGN | UroGen Pharma Ltd | $253.69M | +4438.28% |
| CRVS | Corvus Pharmaceuticals Inc | $253.19M | +4429.43% |
| ZNTL | Zentalis Pharmaceuticals Inc | $253.07M | +4427.12% |
| LXEO | Lexeo Therapeutics Inc | $250.36M | +4378.64% |
| SABS | SAB Biotherapeutics Inc | $248.47M | +4344.91% |
| TECX | AvroBio Inc | $246.58M | +4311.04% |
| HRTX | Heron Therapeutics Inc | $246.22M | +4304.58% |
| ARCT | Arcturus Therapeutics Holdings Inc | $245.41M | +4290.18% |
| MGTX | MeiraGTx Holdings plc | $244.66M | +4276.65% |
| OCS | Oculis Holding AG | $243.26M | +4251.78% |
| STRO | Sutro Biopharma Inc | $241.99M | +4228.94% |
| IVVD | Invivyd Inc | $241.74M | +4224.54% |
| ALEC | Alector Inc | $239.92M | +4191.88% |
| ASMB | Assembly Biosciences Inc | $235.51M | +4113.02% |
| RLMD | Relmada Therapeutics Inc | $235.36M | +4110.43% |
| DSGN | Design Therapeutics Inc | $230.44M | +4022.40% |
| ZURA | Zura Bio Ltd - Class A | $228.64M | +3990.18% |
| VSTM | Verastem Inc | $227.81M | +3975.28% |
| OVID | Ovid Therapeutics Inc | $225.63M | +3936.28% |
| FHTX | Foghorn Therapeutics Inc | $222.17M | +3874.36% |
| SVRA | Savara Inc | $221.65M | +3865.03% |
| VYGR | Voyager Therapeutics Inc | $219.32M | +3823.52% |
| MGNX | Macrogenics Inc | $217.87M | +3797.55% |
| IMRX | Immuneering Corp Class A | $214.81M | +3742.75% |
| VTYX | Ventyx Biosciences Inc | $211.47M | +3682.92% |
| LRMR | Larimar Therapeutics Inc | $208.51M | +3630.07% |
| IMAB | I-Mab | $206.71M | +3597.82% |
| SNSE | Sensei Biotherapeutics Inc | $205.38M | +3574.08% |
| CMPX | Compass Therapeutics Inc | $205.17M | +3570.30% |
| PLRX | Pliant Therapeutics Inc | $202.60M | +3524.26% |
| CADL | Candel Therapeutics Inc | $201.92M | +3512.16% |
| TIL | Instil Bio Inc | $200.43M | +3485.47% |
| CBIO | N/A | $199.13M | +3462.25% |
| ACRS | Aclaris Therapeutics Inc | $198.72M | +3454.92% |
| ABEO | Abeona Therapeutics Inc | $198.49M | +3450.88% |
| MGX | Metagenomi Inc | $196.95M | +3423.31% |
| ABSI | Absci Corp | $195.59M | +3398.98% |
| MIST | Milestone Pharmaceuticals Inc | $193.73M | +3365.72% |
| PBYI | Puma Biotechnology Inc | $192.70M | +3347.21% |
| TARA | Protara Therapeutics Inc | $191.92M | +3333.33% |
| IMUX | Immunic Inc | $189.74M | +3294.31% |
| BNTC | Benitec Biopharma Inc | $187.00M | +3245.26% |
| AGEN | Agenus Inc | $186.46M | +3235.53% |
| INBX | Inhibrx Biosciences Inc | $183.97M | +3191.00% |
| KRRO | Korro Bio Inc | $183.62M | +3184.83% |
| VXRT | Vaxart Inc | $180.06M | +3121.02% |
| NBY | Stablecoin Development Corp | $179.74M | +3115.44% |
| TRVI | Trevi Therapeutics Inc | $179.61M | +3112.99% |
| IVA | Inventiva | $178.52M | +3093.52% |
| ALXO | Alx Oncology Holdings Inc | $178.33M | +3090.13% |
| NAUT | Nautilus Biotechnology Inc | $177.78M | +3080.30% |
| HLVX | HilleVax Inc | $174.91M | +3029.05% |
| IKT | Inhibikase Therapeutics Inc | $173.33M | +3000.76% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $172.19M | +2980.28% |
| AURA | Aura Biosciences Inc | $169.43M | +2930.95% |
| ACET | Adicet Bio Inc | $169.38M | +2930.09% |
| RAPT | RAPT Therapeutics Inc | $165.74M | +2864.92% |
| XLO | Xilio Therapeutics Inc | $163.49M | +2824.63% |
| GYRE | Gyre Therapeutics Inc | $162.01M | +2798.30% |
| RNAZ | TransCode Therapeutics Inc | $157.16M | +2711.54% |
| CGEN | Compugen Ltd | $156.57M | +2700.89% |
| PEPG | PepGen Inc | $156.29M | +2695.97% |
| NMRA | Neumora Therapeutics Inc | $153.88M | +2652.72% |
| CLYM | Eliem Therapeutics Inc | $152.37M | +2625.80% |
| EDIT | Editas Medicine Inc | $149.34M | +2571.52% |
| CRBU | Caribou Biosciences Inc | $149.00M | +2565.44% |
| CABA | Cabaletta Bio Inc | $148.15M | +2550.20% |
| IMMP | Immutep Ltd | $147.20M | +2533.31% |
| ELDN | Eledon Pharmaceuticals Inc | $146.67M | +2523.74% |
| CMRX | Chimerix Inc | $146.01M | +2511.95% |
| OPT | Opthea Ltd | $145.77M | +2507.69% |
| PTHS | Channel Therapeutics Corporation | $145.38M | +2500.68% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $144.48M | +2484.62% |
| DTIL | Precision Biosciences Inc | $143.89M | +2474.08% |
| BOLD | Boundless Bio Inc | $140.97M | +2421.82% |
| XBIT | XBiotech Inc | $139.84M | +2401.54% |
| PGEN | Precigen Inc | $138.63M | +2379.91% |
| MNPR | Monopar Therapeutics Inc | $137.98M | +2368.40% |
| ACIU | AC Immune SA | $137.42M | +2358.34% |
| IMA | Ikena Oncology Inc | $136.68M | +2345.12% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $135.37M | +2321.65% |
| TNYA | Tenaya Therapeutics Inc | $135.07M | +2316.28% |
| ABOS | Acumen Pharmaceuticals Inc | $133.63M | +2290.50% |
| PALI | Palisade Bio Inc | $133.31M | +2284.88% |
| AVXL | Anavex Life Sciences Corporation | $132.99M | +2279.05% |
| BDTX | Black Diamond Therapeutics Inc | $132.92M | +2277.85% |
| CTXR | Citius Pharmaceuticals Inc | $132.54M | +2271.03% |
| KPTI | Karyopharm Therapeutics Inc | $131.42M | +2250.93% |
| ARTV | Artiva Biotherapeutics Inc | $130.94M | +2242.40% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $130.63M | +2236.91% |
| CDXS | Codexis Inc | $129.37M | +2214.31% |
| GOSS | Gossamer Bio Inc | $128.90M | +2205.89% |
| WHWK | Whitehawk Therapeutics Inc | $127.23M | +2176.05% |
| RPTX | Repare Therapeutics Inc | $126.75M | +2167.39% |
| RZLT | Rezolute Inc | $125.46M | +2144.35% |
| TENX | Tenax Therapeutics Inc | $123.18M | +2103.54% |
| GBIO | Generation Bio Company | $121.90M | +2080.61% |
| SRZN | Surrozen Inc | $120.71M | +2059.37% |
| PRLD | Prelude Therapeutics Inc | $119.64M | +2040.29% |
| MCRB | Seres Therapeutics Inc | $117.62M | +2004.08% |
| YMAB | Y-Mabs Therapeutics Inc | $117.21M | +1996.80% |
| SGMT | Sagimet Biosciences Inc - Class A | $116.48M | +1983.76% |
| AVTX | Avalo Therapeutics Inc | $116.46M | +1983.33% |
| SLN | Silence Therapeutics Plc | $115.12M | +1959.45% |
| NAGE | Niagen Bioscience Inc | $114.33M | +1945.24% |
| SLS | SELLAS Life Sciences Group Inc | $114.18M | +1942.52% |
| HUMA | Humacyte Inc | $110.56M | +1877.76% |
| EPIX | Essa Pharma Inc | $110.50M | +1876.78% |
| KLRS | Kalaris Therapeutics Inc | $109.81M | +1864.31% |
| FGEN | FibroGen Inc | $109.63M | +1861.16% |
| LCTX | Lineage Cell Therapeutics Inc | $109.53M | +1859.45% |
| SAVA | Cassava Sciences Inc. | $108.37M | +1838.59% |
| ACRV | Acrivon Therapeutics Inc | $107.83M | +1829.02% |
| CELU | Celularity Inc - Class A | $107.33M | +1820.02% |
| DRTS | Alpha Tau Medical Ltd | $105.65M | +1790.02% |
| CAMP | CAMP4 Therapeutics Corp | $105.46M | +1786.53% |
| PLX | Protalix BioTherapeutics Inc | $102.34M | +1730.70% |
| STTK | Shattuck Labs Inc | $102.12M | +1726.85% |
| OBIO | Orchestra BioMed Holdings Inc | $100.66M | +1700.68% |
| VTVT | vTv Therapeutics Inc - Class A | $99.49M | +1679.86% |
| GUTS | Fractyl Health Inc | $99.39M | +1677.91% |
| PRQR | ProQR Therapeutics N.V | $99.14M | +1673.48% |
| AARD | Aardvark Therapeutics Inc | $98.59M | +1663.69% |
| PMVP | PMV Pharmaceuticals Inc | $96.56M | +1627.41% |
| IMMX | Immix Biopharma Inc | $95.82M | +1614.06% |
| DWTX | Virios Therapeutics Inc | $95.21M | +1603.18% |
| NERV | Minerva Neurosciences Inc | $94.03M | +1582.06% |
| BRNS | Barinthus Biotherapeutics Plc. | $92.14M | +1548.35% |
| ANTX | AN2 Therapeutics Inc | $87.49M | +1465.13% |
| MOLN | Molecular Partners AG | $87.40M | +1463.44% |
| EPRX | Eupraxia Pharmaceuticals Inc | $86.15M | +1441.15% |
| IBIO | iBio Inc | $85.83M | +1435.49% |
| FBRX | Forte Biosciences Inc | $82.78M | +1380.84% |
| MDWD | MediWound Ltd | $79.98M | +1330.81% |
| ATYR | Atyr Pharma Inc | $79.65M | +1324.94% |
| ADAG | Adagene Inc | $78.26M | +1300.06% |
| ADVM | Adverum Biotechnologies Inc | $72.40M | +1195.19% |
| FENC | Fennec Pharmaceuticals Inc | $71.82M | +1184.83% |
| ATHA | Athira Pharma Inc | $71.59M | +1180.68% |
| HYPD | Eyenovia Inc | $70.07M | +1153.42% |
| ARMP | Armata Pharmaceuticals Inc | $69.80M | +1148.66% |
| ACOG | Alpha Cognition Inc | $69.25M | +1138.79% |
| KZR | Kezar Life Sciences Inc | $68.00M | +1116.44% |
| NBTX | Nanobiotix | $67.76M | +1112.16% |
| PMN | ProMIS Neurosciences Inc | $67.41M | +1105.93% |
| IRD | Ocuphire Pharma Inc | $66.79M | +1094.76% |
| GRCE | Acasti Pharma Inc | $66.65M | +1092.38% |
| ALDX | Aldeyra Therapeutics Inc | $66.48M | +1089.32% |
| MURA | Mural Oncology plc | $65.76M | +1076.35% |
| ALGS | Aligos Therapeutics Inc | $64.56M | +1054.88% |
| UNCY | Unicycive Therapeutics Inc | $64.41M | +1052.16% |
| PYXS | Pyxis Oncology Inc | $64.30M | +1050.27% |
| QTTB | Q32 Bio Inc | $63.67M | +1039.09% |
| EQ | Equillium Inc | $63.08M | +1028.50% |
| IPHA | Innate Pharma | $62.69M | +1021.51% |
| MRSN | Mersana Therapeutics Inc | $62.69M | +1021.40% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $62.12M | +1011.22% |
| CNTB | Connect Biopharma Holdings Ltd | $60.07M | +974.53% |
| SGMO | Sangamo Therapeutics Inc | $59.97M | +972.72% |
| KLTO | Klotho Neurosciences Inc Com | $59.74M | +968.64% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $59.74M | +968.64% |
| SPRO | Spero Therapeutics Inc | $59.02M | +955.83% |
| CNTX | Context Therapeutics Inc | $58.86M | +952.94% |
| HOWL | Werewolf Therapeutics Inc | $58.02M | +937.96% |
| LITS | Lite Strategy Inc | $57.79M | +933.79% |
| OCGN | Ocugen Inc | $56.91M | +917.98% |
| ATHE | Alterity Therapeutics Ltd | $56.86M | +917.22% |
| KTTA | Pasithea Therapeutics Corp | $56.35M | +908.14% |
| SPRB | Spruce Biosciences Inc | $56.17M | +904.76% |
| PMCB | PharmaCyte Biotech Inc | $55.87M | +899.53% |
| RLYB | Rallybio Corp | $54.47M | +874.45% |
| COYA | Coya Therapeutics Inc | $53.27M | +852.97% |
| DMAC | DiaMedica Therapeutics Inc | $53.08M | +849.55% |
| LVTX | LAVA Therapeutics NV | $51.91M | +828.71% |
| RANI | Rani Therapeutics Holdings Inc Class A | $51.88M | +828.07% |
| PHXM | PHAXIAM Therapeutics SA ADR | $51.31M | +817.84% |
| INO | Inovio Pharmaceuticals Inc | $49.78M | +790.47% |
| JAGX | Jaguar Health Inc | $49.47M | +785.01% |
| CRDF | Cardiff Oncology Inc | $49.17M | +779.64% |
| IFRX | InflaRx N.V. | $48.94M | +775.51% |
| VTGN | VistaGen Therapeutics Inc | $48.56M | +768.77% |
| BOLT | Bolt Biotherapeutics Inc | $48.03M | +759.16% |
| GRDX | Entero Therapeutics Inc | $47.97M | +758.06% |
| APRE | Aprea Therapeutics Inc | $47.61M | +751.74% |
| BMEA | Biomea Fusion Inc | $46.38M | +729.79% |
| ATNM | Actinium Pharmaceuticals Inc | $45.44M | +712.84% |
| AKTX | Akari Therapeutics Plc | $45.38M | +711.74% |
| ICCC | Immucell Corp | $44.11M | +689.06% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $43.47M | +677.65% |
| VERU | Veru Inc | $43.08M | +670.71% |
| MNOV | Medicinova Inc | $42.70M | +663.95% |
| VANI | Vivani Medical Inc | $42.35M | +657.66% |
| ACHV | Achieve Life Sciences Inc | $41.79M | +647.58% |
| MREO | Mereo Biopharma Group Plc | $40.61M | +626.55% |
| IOBT | IO Biotech Inc | $39.96M | +614.78% |
| BLRX | Bioline Rx Ltd | $38.80M | +594.04% |
| VRCA | Verrica Pharmaceuticals Inc | $38.79M | +593.85% |
| TOVX | Theriva Biologics Inc | $38.25M | +584.22% |
| SNTI | Senti Biosciences Inc | $38.24M | +584.10% |
| NXTC | Nextcure Inc | $37.98M | +579.37% |
| ATOS | Atossa Therapeutics Inc | $37.94M | +578.77% |
| PASG | Passage Bio Inc | $36.46M | +552.27% |
| CGTX | Cognition Therapeutics Inc | $36.14M | +546.51% |
| LYRA | Lyra Therapeutics Inc | $36.11M | +545.94% |
| MAIA | MAIA Biotechnology Inc | $35.32M | +531.89% |
| ALLR | Allarity Therapeutics Inc | $34.92M | +524.74% |
| NEUP | Neuphoria Therapeutics Inc | $34.81M | +522.70% |
| APLT | Applied Therapeutics Inc | $34.37M | +514.92% |
| ITRM | Iterum Therapeutics Plc | $32.50M | +481.45% |
| GNLX | Genelux Corp | $32.37M | +479.11% |
| GNTA | Genenta Science SpA | $31.89M | +470.47% |
| CUE | Cue Biopharma Inc | $30.88M | +452.36% |
| CING | Cingulate Inc | $30.86M | +452.09% |
| SLGL | Sol-Gel Technologies Ltd | $29.92M | +435.19% |
| HURA | TuHURA Biosciences Inc | $29.70M | +431.39% |
| CRIS | Curis Inc | $29.69M | +431.06% |
| CSBR | Champions Oncology Inc | $28.45M | +408.89% |
| DARE | Dare Bioscience Inc | $27.83M | +397.82% |
| NCNA | NuCana plc | $27.55M | +392.92% |
| HCWB | HCW Biologics Inc | $27.34M | +389.13% |
| SER | AgeX Therapeutics Inc | $27.30M | +388.35% |
| BCTX | BriaCell Therapeutics Corp - New | $27.07M | +384.28% |
| QNCX | Quince Therapeutics Inc | $26.62M | +376.26% |
| INAB | IN8bio Inc | $26.27M | +369.86% |
| PLUR | Pluri Inc | $26.06M | +366.14% |
| VYNE | VYNE Therapeutics Inc | $25.87M | +362.84% |
| INMB | INmune Bio Inc | $25.82M | +361.86% |
| TVRD | Cara Therapeutics Inc | $25.82M | +361.84% |
| CASI | CASI Pharmaceuticals Inc | $25.65M | +358.86% |
| NVCT | Nuvectis Pharma Inc | $25.40M | +354.35% |
| LPCN | Lipocine Inc | $25.36M | +353.63% |
| PDSB | PDS Biotechnology Corporation | $24.66M | +341.20% |
| RNTX | Rein Therapeutics Inc | $24.16M | +332.16% |
| EVAX | Evaxion Biotech A/S | $23.64M | +322.93% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $23.56M | +321.46% |
| MBRX | Moleculin Biotech Inc | $23.36M | +317.94% |
| HYFT | MindWalk Holdings Corp | $23.17M | +314.43% |
| CVM | Cel-Sci Corp | $22.89M | +309.56% |
| ELTX | Elicio Therapeutics Inc | $22.69M | +305.89% |
| PYPD | Polypid Ltd | $22.31M | +299.05% |
| OTLK | Outlook Therapeutics Inc | $21.89M | +291.64% |
| PLRZ | Polyrizon Ltd | $21.44M | +283.49% |
| KPRX | Kiora Pharmaceuticals Inc | $21.23M | +279.73% |
| LGVN | Longeveron Inc - Class A | $21.21M | +279.43% |
| JSPR | Jasper Therapeutics Inc | $21.18M | +278.96% |
| MENS | Jyong Biotech Ltd | $20.78M | +271.70% |
| GNPX | Genprex Inc | $20.31M | +263.26% |
| LPTX | Leap Therapeutics Inc | $20.04M | +258.53% |
| ATRA | Atara Biotherapeutics Inc | $20.00M | +257.73% |
| PSTV | Plus Therapeutics Inc | $19.92M | +256.28% |
| APVO | Aptevo Therapeutics Inc | $19.90M | +256.03% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $19.79M | +253.97% |
| ABVC | ABVC BioPharma Inc | $19.73M | +253.00% |
| SKYE | Skye Bioscience Inc | $19.42M | +247.35% |
| GANX | Gain Therapeutics Inc | $18.74M | +235.21% |
| APM | Aptorum Group Limited Class A Ordinary Shares | $18.69M | +234.37% |
| TTRX | Turn Therapeutics Inc | $18.64M | +233.53% |
| GLMD | Galmed Pharmaceuticals Ltd | $18.63M | +233.22% |
| BYSI | BeyondSpring Inc | $18.41M | +229.27% |
| BDRX | Biodexa Pharmaceuticals Plc | $18.15M | +224.63% |
| EVGN | Evogene Ltd | $17.95M | +221.07% |
| BIVI | BioVie Inc - Class A | $17.51M | +213.32% |
| MRKR | Marker Therapeutics Inc | $17.43M | +211.88% |
| PHIO | Phio Pharmaceuticals Corp | $17.41M | +211.48% |
| IBO | Impact BioMedical Inc | $17.09M | +205.65% |
| MBIO | Mustang Bio Inc | $16.58M | +196.64% |
| ANVS | Annovis Bio Inc | $16.24M | +190.59% |
| GALT | Galectin Therapeutics Inc | $15.76M | +181.91% |
| QNRX | Quoin Pharmaceuticals Ltd | $15.69M | +180.73% |
| ONCT | Oncternal Therapeutics Inc | $15.60M | +179.09% |
| IMRN | Immuron Ltd | $15.12M | +170.53% |
| CRVO | CervoMed Inc | $15.11M | +170.36% |
| PPCB | Propanc Biopharma Inc | $15.11M | +170.33% |
| REVB | Revelation Biosciences Inc | $15.04M | +169.13% |
| CLRB | Cellectar Biosciences Inc | $14.98M | +167.95% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $14.98M | +167.89% |
| ELAB | PMGC Holdings Inc | $14.94M | +167.23% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $14.88M | +166.27% |
| ANIX | Anixa Biosciences Inc | $14.87M | +165.92% |
| ONCO | Onconetix Inc | $14.83M | +165.33% |
| SYBX | Synlogic Inc | $14.61M | +161.38% |
| CMND | Clearmind Medicine Inc | $14.52M | +159.81% |
| MTVA | MetaVia Inc | $14.39M | +157.39% |
| LSTA | Lisata Therapeutics Inc | $14.06M | +151.50% |
| RNXT | RenovoRx Inc | $13.96M | +149.80% |
| ADTX | Aditxt Inc | $13.91M | +148.78% |
| CMMB | Chemomab Therapeutics Ltd | $13.81M | +147.08% |
| YDES | YD Bio Ltd | $13.78M | +146.50% |
| PTN | Palatin Technologies Inc | $13.23M | +136.59% |
| ENTX | Entera Bio Ltd | $13.13M | +134.87% |
| PBM | Psyence Biomedical Ltd | $12.81M | +129.16% |
| XCUR | Exicure Inc | $12.76M | +128.18% |
| ARTL | Artelo Biosciences Inc | $12.52M | +123.94% |
| EDSA | Edesa Biotech Inc | $12.38M | +121.55% |
| KALA | Kala Bio Inc | $12.32M | +120.36% |
| INTS | Intensity Therapeutics Inc | $12.29M | +119.87% |
| AZTR | Azitra Inc | $12.13M | +116.94% |
| NRXP | NRX Pharmaceuticals Inc | $11.90M | +112.93% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $11.64M | +108.25% |
| SCNI | Scinai Immunotherapeutics Ltd | $11.63M | +107.98% |
| NCEL | NLS Pharmaceutics Ltd | $11.45M | +104.74% |
| GRI | GRI Bio Inc | $11.34M | +102.84% |
| ICU | SeaStar Medical Holding Corp | $11.26M | +101.48% |
| TPST | Tempest Therapeutics Inc | $10.75M | +92.27% |
| ERNA | Ernexa Therapeutics Inc | $10.54M | +88.60% |
| GLSI | Greenwich LifeSciences Inc | $10.51M | +87.93% |
| INKT | MiNK Therapeutics Inc | $10.38M | +85.63% |
| NNVC | NanoViricides Inc | $10.22M | +82.81% |
| HIND | ReShape Lifesciences Inc | $10.19M | +82.21% |
| LNAI | Lunai Bioworks Inc | $9.86M | +76.40% |
| CLDI | Calidi Biotherapeutics Inc | $9.59M | +71.57% |
| CDIO | Cardio Diagnostics Holdings Inc | $9.56M | +71.01% |
| ACXP | Acurx Pharmaceuticals Inc | $9.54M | +70.66% |
| CANF | Can-Fite Biopharma Ltd | $9.51M | +70.20% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $9.42M | +68.55% |
| IGC | IGC Pharma Inc | $9.19M | +64.31% |
| CLGN | CollPlant Biotechnologies Ltd New | $9.18M | +64.28% |
| ACTU | Actuate Therapeutics Inc | $8.91M | +59.41% |
| NRXS | Neuraxis Inc | $8.75M | +56.45% |
| AEON | AEON Biopharma Inc - Class A | $8.63M | +54.38% |
| CALC | CalciMedica Inc | $8.61M | +54.01% |
| AIM | AIM ImmunoTech Inc. | $8.59M | +53.58% |
| BCAB | BioAtla Inc | $8.57M | +53.24% |
| CDT | CDT Equity Inc | $8.55M | +52.99% |
| CYCN | Cyclerion Therapeutics Inc | $8.51M | +52.15% |
| SLRX | Decoy Therapeutics Inc | $8.42M | +50.68% |
| CURX | Curanex Pharmaceuticals Inc | $8.41M | +50.47% |
| ONCY | Oncolytics Biotech Inc | $8.16M | +45.99% |
| TRAW | Traws Pharma Inc | $8.16M | +45.90% |
| IMNN | Imunon Inc | $8.02M | +43.45% |
| GDTC | CytoMed Therapeutics Ltd | $7.98M | +42.84% |
| XBIO | Xenetic Biosciences Inc | $7.91M | +41.48% |
| DYAI | Dyadic International Inc DE | $7.81M | +39.71% |
| BGMS | Bio Green Med Solution Inc | $7.56M | +35.31% |
| OGEN | Oragenics Inc | $7.49M | +33.98% |
| DRMA | Dermata Therapeutics Inc | $7.47M | +33.55% |
| COCP | Cocrystal Pharma Inc | $7.43M | +32.84% |
| VIVS | VivoSim Labs Inc | $7.39M | +32.13% |
| TELO | Telomir Pharmaceuticals Inc | $7.34M | +31.33% |
| OSTX | OS Therapies Inc | $7.30M | +30.58% |
| LTRN | Lantern Pharma Inc | $7.22M | +29.21% |
| ASBP | Aspire Biopharma Holdings Inc | $7.12M | +27.32% |
| SILO | SILO Pharma Inc | $7.02M | +25.55% |
| SNGX | Soligenix Inc | $6.92M | +23.84% |
| NTRB | Nutriband Inc | $6.89M | +23.30% |
| INDP | Indaptus Therapeutics Inc | $6.84M | +22.36% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $6.76M | +20.99% |
| GTBP | GT Biopharma Inc | $6.76M | +20.91% |
| APLM | Apollomics Inc - Class A | $6.71M | +20.11% |
| CELZ | Creative Medical Technology Holdings Inc | $6.44M | +15.22% |
| FBLG | FibroBiologics Inc | $5.94M | +6.23% |
| MTNB | Matinas Biopharma Holdings Inc | $5.87M | +5.08% |
| KAPA | Kairos Pharma Ltd | $5.74M | +2.75% |
| VRAX | Virax Biolabs Group Ltd - Class A | $5.72M | +2.24% |
| ENVB | Enveric Biosciences Inc | $5.52M | -1.23% |
| ADIL | Adial Pharmaceuticals Inc | $5.23M | -6.49% |
| BBLG | Bone Biologics Corp | $4.98M | -10.92% |
| TVGN | Tevogen Bio Holdings Inc | $4.92M | -11.97% |
| LEXX | Lexaria Bioscience Corp | $4.78M | -14.47% |
| ADXN | Addex Therapeutics Ltd | $4.76M | -14.86% |
| CNSP | Cns Pharmaceuticals Inc | $4.65M | -16.76% |
| OKYO | OKYO Pharma Ltd - New | $4.64M | -16.93% |
| BRTX | BioRestorative Therapies Inc | $4.64M | -16.99% |
| SLXN | Silexion Therapeutics Corp | $4.60M | -17.67% |
| PCSA | Processa Pharmaceuticals Inc | $4.52M | -19.12% |
| PULM | Pulmatrix Inc | $4.50M | -19.57% |
| PTIX | Protagenic Therapeutics Inc | $4.43M | -20.73% |
| ALZN | Alzamend Neuro Inc | $4.04M | -27.70% |
| EXOZ | Invizyne Technologies Inc | $4.02M | -28.11% |
| JUNS | Jupiter Neurosciences Inc | $3.95M | -29.36% |
| ESLA | Estrella Immunopharma Inc | $3.66M | -34.58% |
| NTHI | NeOnc Technologies Holdings Inc | $3.33M | -40.43% |
| TTNP | Titan Pharmaceuticals Inc (de) | $3.05M | -45.42% |
| GOVX | Geovax Labs Inc | $2.98M | -46.65% |
| CVKD | Cadrenal Therapeutics Inc | $2.86M | -48.80% |
| LIMN | Liminatus Pharma Inc | $2.79M | -50.08% |
| ENSC | Ensysce Biosciences Inc | $2.17M | -61.22% |
| XRTX | XORTX Therapeutics Inc | $2.15M | -61.51% |
| TCRT | Alaunos Therapeutics Inc | $1.88M | -66.31% |
| BCDA | BioCardia Inc | $1.71M | -69.37% |
| ABP | Abpro Holdings, Inc Common Stock | $1.06M | -80.98% |
| NRSN | NeuroSense Therapeutics Ltd | $1.03M | -81.61% |
| BCLI | Brainstorm Cell Therapeutics Inc | $755000.00 | -86.49% |
| ZVSA | ZyVersa Therapeutics Inc | $742223.00 | -86.72% |