Performance analysis of Denali Therapeutics (DNLI)
Annual Return
Over the past 3 years, DNLI has had an average annual return of -6.50%, underperforming the benchmark SPY, which returned +19.62% annual.
Over the past 5 years, DNLI has had an average annual return of -18.08%, underperforming the benchmark SPY, which returned +12.73% annual.
Since Dec 8, 2017, DNLI has had an average annual return of +1.23%, underperforming the benchmark SPY, which returned +14.56% annual.
| 2026 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| +44.34% | -18.99% | -5.04% | -22.83% | -37.65% | -46.75% | +380.84% | -15.69% | +32.11% | -27.09% |
Monthly Return
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Annually Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | +31.67% | -2.58% | -9.35% | -2.50% | +12.40% | +22.24% | -7.35% | +44.34% | |||||
| 2025 | +14.32% | -28.93% | -17.90% | +22.47% | -20.48% | +5.67% | -1.13% | +10.41% | -4.92% | +12.13% | +19.59% | -15.20% | -18.99% |
| 2024 | -25.40% | +23.54% | +3.74% | -24.75% | +20.21% | +25.10% | +4.95% | +0.29% | +19.19% | -10.88% | -3.70% | -18.48% | -5.04% |
| 2023 | +8.85% | -10.31% | -15.14% | +7.81% | +21.67% | -2.35% | -3.66% | -18.78% | -10.65% | -8.72% | -1.65% | +15.88% | -22.83% |
| 2022 | -23.28% | -4.85% | -1.19% | -26.02% | +2.05% | +21.16% | +15.60% | -18.66% | +10.91% | -6.55% | +11.26% | -12.85% | -37.65% |
| 2021 | -18.22% | +4.82% | -20.47% | +5.85% | +5.21% | +23.35% | -34.94% | +4.25% | -5.17% | -4.16% | -4.33% | -3.58% | -46.75% |
| 2020 | +32.95% | -14.63% | -11.44% | +24.84% | +27.31% | -13.11% | -3.15% | +36.22% | +12.32% | +19.40% | +42.52% | +37.38% | +380.84% |
| 2019 | -7.75% | +14.17% | +6.70% | +5.39% | -22.07% | +8.86% | +2.84% | -15.68% | -14.90% | +2.28% | +13.54% | -2.09% | -15.69% |
| 2018 | +48.73% | -1.60% | -13.98% | -6.14% | +4.06% | -20.69% | -17.45% | +55.94% | +10.74% | -33.44% | +32.48% | +7.78% | +32.11% |
| 2017 | -27.09% | -27.09% |
Drawdown analysis of Denali Therapeutics (DNLI)
The maximum drawdown for the DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.
The current DNLI drawdown is -74.53%.
Since Dec 8, 2017 DNLI has experienced the following drawdowns:
- 50% or more: 1 time
- 40% or more: 3 times
- 30% or more: 3 times
- 20% or more: 4 times
- 10% or more: 10 times
| Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -87.74% | Dec 22, 2020 | 1077 | Apr 8, 2025 | Ongoing | Ongoing | Ongoing |
| -49.76% | Feb 16, 2018 | 112 | Jul 30, 2018 | 169 | Apr 2, 2019 | 281 |
| -49.54% | Apr 10, 2019 | 234 | Mar 16, 2020 | 54 | Jun 2, 2020 | 288 |
| -29.88% | Dec 8, 2017 | 13 | Dec 28, 2017 | 15 | Jan 22, 2018 | 28 |
| -19.75% | Jun 3, 2020 | 36 | Jul 24, 2020 | 9 | Aug 6, 2020 | 45 |
| -19.59% | Jan 29, 2018 | 5 | Feb 5, 2018 | 9 | Feb 16, 2018 | 14 |
| -13.33% | Nov 12, 2020 | 9 | Nov 25, 2020 | 6 | Dec 4, 2020 | 15 |
| -11.17% | Aug 10, 2020 | 3 | Aug 13, 2020 | 8 | Aug 25, 2020 | 11 |
| -10.43% | Sep 17, 2020 | 5 | Sep 24, 2020 | 9 | Oct 7, 2020 | 14 |
| -10.33% | Oct 13, 2020 | 6 | Oct 21, 2020 | 4 | Oct 27, 2020 | 10 |
| -9.65% | Aug 25, 2020 | 9 | Sep 8, 2020 | 4 | Sep 14, 2020 | 13 |
| -7.28% | Oct 28, 2020 | 2 | Oct 30, 2020 | 3 | Nov 4, 2020 | 5 |
| -3.20% | Jan 23, 2018 | 2 | Jan 25, 2018 | 1 | Jan 26, 2018 | 3 |
| -2.37% | Apr 3, 2019 | 1 | Apr 4, 2019 | 1 | Apr 5, 2019 | 2 |
| -1.33% | Dec 16, 2020 | 1 | Dec 17, 2020 | 1 | Dec 18, 2020 | 2 |
| -0.84% | Dec 4, 2020 | 1 | Dec 7, 2020 | 1 | Dec 8, 2020 | 2 |
| -0.83% | Dec 8, 2020 | 1 | Dec 9, 2020 | 1 | Dec 10, 2020 | 2 |
| -0.46% | Dec 14, 2020 | 1 | Dec 15, 2020 | 1 | Dec 16, 2020 | 2 |
| -0.16% | Aug 6, 2020 | 1 | Aug 7, 2020 | 1 | Aug 10, 2020 | 2 |
| -0.08% | Apr 8, 2019 | 1 | Apr 9, 2019 | 1 | Apr 10, 2019 | 2 |