| REGN | Regeneron Pharmaceuticals Inc | $40.87B | +880693.10% |
| VRTX | Vertex Pharmaceuticals Inc | $26.48B | +570684.48% |
| BNTX | BioNTech SE | $21.10B | +454556.85% |
| RPRX | Royalty Pharma plc - Class A | $19.82B | +426956.36% |
| GMAB | Genmab | $12.38B | +266619.82% |
| JAZZ | Jazz Pharmaceuticals plc | $11.86B | +255494.83% |
| MRNA | Moderna Inc | $11.49B | +247486.21% |
| ARGX | Argen X SE | $8.68B | +187027.11% |
| BMRN | Biomarin Pharmaceutical Inc | $8.59B | +185051.21% |
| ONC | BeiGene Ltd | $8.55B | +184245.24% |
| SVA | Sinovac Biotech Ltd | $8.54B | +183988.90% |
| INCY | Incyte Corp | $7.34B | +158070.54% |
| ROIV | Roivant Sciences Ltd | $5.71B | +122932.05% |
| ALNY | Alnylam Pharmaceuticals Inc | $4.97B | +106933.00% |
| AAPG | Ascentage Pharma Group International | $3.97B | +85376.31% |
| IONS | Ionis Pharmaceuticals Inc | $3.45B | +74252.78% |
| GLPG | Galapagos NV | $3.41B | +73285.09% |
| PCVX | Vaxcyte Inc | $3.35B | +72061.81% |
| SRPT | Sarepta Therapeutics Inc | $3.18B | +68411.51% |
| PTCT | PTC Therapeutics Inc | $2.87B | +61734.14% |
| CRSP | CRISPR Therapeutics AG | $2.73B | +58646.12% |
| FTRE | Fortrea Holdings Inc | $2.68B | +57731.90% |
| HALO | Halozyme Therapeutics Inc | $2.67B | +57501.70% |
| NBP | NovaBridge Biosciences. | $2.61B | +56213.94% |
| EXEL | Exelixis Inc | $2.59B | +55796.40% |
| TECH | Bio-Techne Corp | $2.55B | +54869.85% |
| ENLV | Enlivex Ltd | $2.33B | +50050.82% |
| ARWR | Arrowhead Pharmaceuticals Inc | $2.27B | +48785.02% |
| RVMD | Revolution Medicines Inc | $2.25B | +48471.92% |
| INSM | Insmed Inc | $2.08B | +44638.43% |
| ASND | Ascendis Pharma A/S | $2.01B | +43119.14% |
| INVA | Innoviva Inc | $1.84B | +39481.62% |
| TLX | Telix Pharmaceuticals Ltd | $1.77B | +38066.26% |
| KYMR | Kymera Therapeutics Inc | $1.67B | +35870.17% |
| ACAD | Acadia Pharmaceuticals Inc | $1.61B | +34495.47% |
| LEGN | Legend Biotech Corp | $1.60B | +34312.71% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $1.53B | +32919.50% |
| TGTX | TG Therapeutics Inc | $1.53B | +32849.07% |
| GPCR | Structure Therapeutics Inc | $1.51B | +32402.67% |
| BEAM | Beam Therapeutics Inc | $1.48B | +31813.75% |
| PRAX | Praxis Precision Medicines Inc | $1.46B | +31369.87% |
| CRNX | Crinetics Pharmaceuticals Inc | $1.40B | +30100.93% |
| KRYS | Krystal Biotech Inc | $1.40B | +30007.05% |
| XENE | Xenon Pharmaceuticals Inc | $1.39B | +29788.15% |
| BBIO | BridgeBio Pharma Inc | $1.37B | +29447.00% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.34B | +28769.01% |
| NUVL | Nuvalent Inc - Class A | $1.33B | +28588.53% |
| ABCL | AbCellera Biologics Inc | $1.31B | +28070.52% |
| RARE | Ultragenyx Pharmaceutical Inc | $1.30B | +27831.03% |
| APGE | Apogee Therapeutics Inc | $1.29B | +27780.47% |
| CYTK | Cytokinetics Inc | $1.27B | +27345.65% |
| HRMY | Harmony Biosciences Holdings Inc | $1.27B | +27310.00% |
| DNLI | Denali Therapeutics Inc | $1.27B | +27184.98% |
| DNTH | Dianthus Therapeutics Inc | $1.25B | +26772.50% |
| MDGL | Madrigal Pharmaceuticals Inc | $1.23B | +26351.01% |
| AGIO | Agios Pharmaceuticals Inc | $1.18B | +25438.58% |
| CAI | Caris Life Sciences Inc - Class A | $1.16B | +24951.47% |
| CPRX | Catalyst Pharmaceuticals Inc | $1.15B | +24632.97% |
| CVAC | CureVac N.V. | $1.14B | +24439.20% |
| CGON | Cg Oncology Inc | $1.14B | +24366.85% |
| ZLAB | Zai Lab Ltd | $1.10B | +23515.02% |
| APLS | Apellis Pharmaceuticals Inc | $1.08B | +23230.43% |
| DYN | Dyne Therapeutics Inc | $1.08B | +23174.78% |
| IMCR | Immunocore Holdings plc | $1.07B | +23005.50% |
| NVAX | Novavax Inc | $1.04B | +22381.94% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $1.03B | +22164.55% |
| IDYA | Ideaya Biosciences Inc | $1.03B | +22105.78% |
| JANX | Janux Therapeutics Inc | $1.03B | +22060.02% |
| VIR | Vir Biotechnology Inc | $1.03B | +22003.13% |
| TERN | Terns Pharmaceuticals Inc | $1.03B | +21992.20% |
| AKRO | Akero Therapeutics Inc | $1.01B | +21571.92% |
| RCUS | Arcus Biosciences Inc | $997.00M | +21387.07% |
| IMVT | Immunovant Inc | $957.01M | +20525.30% |
| FOLD | Amicus Therapeutics Inc | $949.87M | +20371.34% |
| IOVA | Iovance Biotherapeutics Inc | $925.66M | +19849.68% |
| MRUS | Merus N.V | $904.20M | +19386.98% |
| COGT | Cogent Biosciences Inc | $903.01M | +19361.34% |
| MIRM | Mirum Pharmaceuticals Inc | $890.92M | +19100.78% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $849.19M | +18201.53% |
| CRMD | CorMedix Inc | $815.64M | +17478.38% |
| CORT | Corcept Therapeutics Inc | $814.88M | +17462.09% |
| VRDN | Viridian Therapeutics Inc | $789.02M | +16904.68% |
| MESO | Mesoblast Ltd | $782.31M | +16760.06% |
| BLTE | Belite Bio Inc | $780.56M | +16722.33% |
| QURE | uniQure N.V. | $778.71M | +16682.46% |
| SYRE | Spyre Therapeutics Inc | $763.95M | +16364.50% |
| NKTR | Nektar Therapeutics | $763.27M | +16349.81% |
| NTLA | Intellia Therapeutics Inc | $758.78M | +16253.00% |
| IRON | Disc Medicine Inc | $750.21M | +16068.38% |
| ZBIO | Zenas Biopharma Inc | $747.68M | +16013.84% |
| MNKD | Mannkind Corp | $744.40M | +15943.17% |
| XNCR | Xencor Inc | $736.85M | +15780.30% |
| GLUE | Monte Rosa Therapeutics Inc | $736.43M | +15771.29% |
| NAMS | NewAmsterdam Pharma Company NV | $732.64M | +15689.72% |
| OCUL | Ocular Therapeutix Inc | $732.53M | +15687.26% |
| AUPH | Aurinia Pharmaceuticals Inc | $724.00M | +15503.38% |
| AXSM | Axsome Therapeutics Inc | $713.61M | +15279.46% |
| RLAY | Relay Therapeutics Inc | $699.61M | +14977.87% |
| PTGX | Protagonist Therapeutics Inc | $697.46M | +14931.44% |
| ALMS | Alumis Inc | $671.59M | +14373.88% |
| ADMA | Adma Biologics Inc | $665.18M | +14235.86% |
| MLYS | Mineralys Therapeutics Inc | $652.86M | +13970.30% |
| KURA | Kura Oncology Inc | $652.55M | +13963.60% |
| BCYC | Bicycle Therapeutics Plc | $652.40M | +13960.26% |
| SMMT | Summit Therapeutics Inc | $647.86M | +13862.41% |
| ARVN | Arvinas Inc | $647.50M | +13854.74% |
| IBRX | ImmunityBio Inc | $646.64M | +13836.14% |
| CNTA | Centessa Pharmaceuticals plc | $641.76M | +13731.10% |
| VERA | Vera Therapeutics Inc - Class A | $621.74M | +13299.55% |
| IMNM | Immunome Inc | $619.79M | +13257.59% |
| NUVB | Nuvation Bio Inc - Class A | $610.24M | +13051.75% |
| SLNO | Soleno Therapeutics Inc | $608.39M | +13011.81% |
| VKTX | Viking Therapeutics Inc | $608.24M | +13008.66% |
| ACLX | Arcellx Inc | $603.99M | +12917.03% |
| THAR | Tharimmune Inc | $584.65M | +12500.31% |
| WVE | Wave Life Sciences Ltd | $583.54M | +12476.38% |
| TARS | Tarsus Pharmaceuticals Inc | $581.13M | +12424.46% |
| VRNA | Verona Pharma Plc | $572.87M | +12246.36% |
| SEPN | Septerna Inc | $569.69M | +12177.76% |
| TVTX | Travere Therapeutics Inc | $555.19M | +11865.26% |
| BCAX | Bicara Therapeutics Inc | $553.60M | +11831.01% |
| PRTC | PureTech Health plc American Depositary Shares | $553.24M | +11823.32% |
| ABVX | Abivax | $547.14M | +11691.85% |
| IMTX | Immatics N.V | $543.83M | +11620.49% |
| NRIX | Nurix Therapeutics Inc | $535.54M | +11441.81% |
| GLTO | Galecto Inc | $535.44M | +11439.70% |
| SRRK | Scholar Rock Holding Corp | $535.25M | +11435.65% |
| GERN | Geron Corp | $534.12M | +11411.21% |
| OLMA | Olema Pharmaceuticals Inc | $530.64M | +11336.31% |
| AUTL | Autolus Therapeutics plc | $527.07M | +11259.16% |
| CDTX | Cidara Therapeutics Inc | $518.65M | +11077.80% |
| EWTX | Edgewise Therapeutics Inc | $518.52M | +11075.04% |
| FDMT | 4D Molecular Therapeutics Inc | $512.90M | +10953.99% |
| CLDX | Celldex Therapeutics Inc | $511.25M | +10918.41% |
| DAWN | Day One Biopharmaceuticals Inc | $507.83M | +10844.55% |
| VOR | Vor Biopharma Inc | $506.75M | +10821.25% |
| RIGL | Rigel Pharmaceuticals | $504.61M | +10775.17% |
| ARDX | Ardelyx Inc | $504.51M | +10773.00% |
| ORKA | ARCA biopharma Inc | $504.48M | +10772.41% |
| RAPP | Rapport Therapeutics Inc | $497.60M | +10624.07% |
| PHAR | Pharming Group N.V. | $489.37M | +10446.66% |
| VCEL | Vericel Corp | $485.63M | +10366.10% |
| ZYME | Zymeworks BC Inc | $478.21M | +10206.36% |
| SNDX | Syndax Pharmaceuticals Inc | $472.67M | +10086.81% |
| TBPH | Theravance Biopharma Inc | $472.31M | +10079.16% |
| BHVN | Biohaven Ltd | $466.41M | +9951.85% |
| ELVN | Enliven Therapeutics Inc | $464.85M | +9918.36% |
| RVNC | Revance Therapeutics Inc | $461.56M | +9847.50% |
| ERAS | Erasca Inc | $461.23M | +9840.39% |
| ARQT | Arcutis Biotherapeutics Inc | $460.00M | +9813.86% |
| MBX | MBX Biosciences Inc | $452.70M | +9656.49% |
| STOK | Stoke Therapeutics Inc | $443.28M | +9453.38% |
| RYTM | Rhythm Pharmaceuticals Inc | $442.32M | +9432.67% |
| ORIC | ORIC Pharmaceuticals Inc | $436.76M | +9312.97% |
| SLRN | Acelyrin Inc | $436.50M | +9307.41% |
| TNGX | Tango Therapeutics Inc | $435.79M | +9292.07% |
| VNDA | Vanda Pharmaceuticals Inc | $433.52M | +9243.21% |
| SLDB | Solid Biosciences Inc | $422.89M | +9014.07% |
| MAZE | Maze Therapeutics Inc | $419.71M | +8945.47% |
| MPLT | MapLight Therapeutics Inc | $418.79M | +8925.60% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $417.65M | +8900.99% |
| TYRA | Tyra Biosciences Inc | $412.04M | +8780.17% |
| CELC | Celcuity Inc | $410.16M | +8739.74% |
| CGEM | Cullinan Oncology Inc | $402.98M | +8585.00% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $401.29M | +8548.56% |
| MLTX | MoonLake Immunotherapeutics - Class A | $400.37M | +8528.75% |
| ALLO | Allogene Therapeutics Inc | $395.96M | +8433.58% |
| LBRX | LB Pharmaceuticals Inc | $393.48M | +8380.22% |
| SANA | Sana Biotechnology Inc | $373.59M | +7951.57% |
| VALN | Valneva SE | $372.40M | +7925.88% |
| NKTX | Nkarta Inc | $372.07M | +7918.81% |
| CTMX | CytomX Therapeutics Inc | $359.36M | +7644.78% |
| FBIO | Fortress Biotech Inc | $356.87M | +7591.25% |
| PROK | ProKidney Corp - Class A | $351.61M | +7477.76% |
| LYEL | Lyell Immunopharma Inc | $350.63M | +7456.59% |
| PRTA | Prothena Corporation plc | $349.89M | +7440.82% |
| AVBP | ArriVent BioPharma Inc | $349.30M | +7427.91% |
| FULC | Fulcrum Therapeutics Inc | $346.77M | +7373.49% |
| RGNX | Regenxbio Inc | $341.89M | +7268.41% |
| TRDA | Entrada Therapeutics Inc | $335.52M | +7130.99% |
| REPL | Replimune Group Inc | $332.39M | +7063.53% |
| ANAB | AnaptysBio Inc | $329.68M | +7005.26% |
| KALV | KalVista Pharmaceuticals Inc | $328.92M | +6988.73% |
| CCCC | C4 Therapeutics Inc | $328.86M | +6987.52% |
| IPSC | Century Therapeutics Inc | $326.55M | +6937.78% |
| CAPR | Capricor Therapeutics Inc | $326.28M | +6931.97% |
| CBUS | Cibus Global Ltd. Class A | $324.20M | +6887.11% |
| EVMN | Evommune Inc | $322.45M | +6849.46% |
| JBIO | Jade Biosciences Inc | $319.43M | +6784.33% |
| UPB | Upstream Bio Inc | $318.05M | +6754.61% |
| ENTA | Enanta Pharmaceuticals Inc | $314.70M | +6682.41% |
| KROS | Keros Therapeutics Inc | $312.29M | +6630.45% |
| DRUG | Bright Minds Biosciences Inc | $312.15M | +6627.28% |
| MDXG | Mimedx Group Inc | $308.68M | +6552.50% |
| ENGN | enGene Holdings Inc | $307.52M | +6527.67% |
| KOD | Kodiak Sciences Inc | $306.01M | +6494.96% |
| PHAT | Phathom Pharmaceuticals Inc | $305.12M | +6475.86% |
| SION | Sionna Therapeutics Inc | $305.04M | +6474.12% |
| TSHA | Taysha Gene Therapies Inc | $300.35M | +6373.08% |
| PRME | Prime Medicine Inc | $294.73M | +6251.94% |
| OABI | OmniAb Inc | $293.65M | +6228.66% |
| RNA | Atrium Therapeutics Inc | $292.36M | +6200.86% |
| CLLS | Cellectis | $289.19M | +6132.48% |
| RNAC | Cartesian Therapeutics Inc | $288.39M | +6115.32% |
| EYPT | EyePoint Pharmaceuticals Inc | $288.22M | +6111.57% |
| SPRY | ARS Pharmaceuticals Inc | $287.57M | +6097.65% |
| OMER | Omeros Corporation | $286.17M | +6067.52% |
| RCKT | Rocket Pharmaceuticals Inc | $285.41M | +6051.01% |
| FATE | Fate Therapeutics Inc | $284.92M | +6040.43% |
| ALT | Altimmune Inc | $279.93M | +5932.95% |
| THRD | Third Harmonic Bio Inc | $279.84M | +5930.95% |
| ZVRA | Zevra Therapeutics Inc | $278.58M | +5903.86% |
| ABUS | Arbutus Biopharma Corp | $277.16M | +5873.36% |
| ANRO | Alto Neuroscience Inc | $276.26M | +5853.86% |
| GHRS | GH Research PLC | $275.27M | +5832.48% |
| LENZ | LENZ Therapeutics Inc | $272.54M | +5773.60% |
| SEER | Seer Inc - Class A | $272.13M | +5764.91% |
| ATXS | Astria Therapeutics Inc | $271.87M | +5759.18% |
| XOMA | XOMA Royalty Corp | $271.86M | +5759.01% |
| XFOR | X4 Pharmaceuticals Inc | $270.28M | +5725.02% |
| TRML | Tourmaline Bio Inc | $269.30M | +5703.77% |
| ORMP | Oramed Pharmaceuticals Inc | $268.85M | +5694.12% |
| LXRX | Lexicon Pharmaceuticals Inc | $268.82M | +5693.51% |
| AVIR | Atea Pharmaceuticals Inc | $267.08M | +5655.95% |
| DBVT | DBV Technologies | $266.40M | +5641.38% |
| CHRS | Coherus Biosciences Inc | $266.02M | +5633.23% |
| ATAI | ATAI Life Sciences N.V. | $264.88M | +5608.56% |
| PVLA | Palvella Therapeutics Inc | $263.76M | +5584.46% |
| NGNE | Neoleukin Therapeutics Inc | $263.14M | +5571.14% |
| ANNX | Annexon Inc | $262.89M | +5565.69% |
| TCRX | Tscan Therapeutics Inc | $262.23M | +5551.40% |
| CTNM | Contineum Therapeutics Inc - Class A | $261.35M | +5532.52% |
| PHVS | Pharvaris NV | $259.79M | +5498.88% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $257.91M | +5458.45% |
| KYTX | Kyverna Therapeutics Inc | $257.02M | +5439.31% |
| URGN | UroGen Pharma Ltd | $253.69M | +5367.46% |
| CRVS | Corvus Pharmaceuticals Inc | $253.19M | +5356.79% |
| ZNTL | Zentalis Pharmaceuticals Inc | $253.07M | +5354.01% |
| LXEO | Lexeo Therapeutics Inc | $250.36M | +5295.60% |
| SABS | SAB Biotherapeutics Inc | $248.47M | +5254.97% |
| TECX | AvroBio Inc | $246.58M | +5214.16% |
| HRTX | Heron Therapeutics Inc | $246.22M | +5206.38% |
| ARCT | Arcturus Therapeutics Holdings Inc | $245.41M | +5189.03% |
| MGTX | MeiraGTx Holdings plc | $244.66M | +5172.74% |
| OCS | Oculis Holding AG | $243.26M | +5142.76% |
| STRO | Sutro Biopharma Inc | $241.99M | +5115.26% |
| IVVD | Invivyd Inc | $241.74M | +5109.96% |
| ALEC | Alector Inc | $239.92M | +5070.60% |
| ASMB | Assembly Biosciences Inc | $235.51M | +4975.60% |
| RLMD | Relmada Therapeutics Inc | $235.36M | +4972.47% |
| DSGN | Design Therapeutics Inc | $230.44M | +4866.42% |
| ZURA | Zura Bio Ltd - Class A | $228.64M | +4827.61% |
| VSTM | Verastem Inc | $227.81M | +4809.66% |
| OVID | Ovid Therapeutics Inc | $225.63M | +4762.67% |
| FHTX | Foghorn Therapeutics Inc | $222.17M | +4688.08% |
| SVRA | Savara Inc | $221.65M | +4676.83% |
| VYGR | Voyager Therapeutics Inc | $219.32M | +4626.83% |
| MGNX | Macrogenics Inc | $217.87M | +4595.54% |
| IMRX | Immuneering Corp Class A | $214.81M | +4529.52% |
| VTYX | Ventyx Biosciences Inc | $211.47M | +4457.44% |
| LRMR | Larimar Therapeutics Inc | $208.51M | +4393.77% |
| IMAB | I-Mab | $206.71M | +4354.91% |
| SNSE | Sensei Biotherapeutics Inc | $205.38M | +4326.31% |
| CMPX | Compass Therapeutics Inc | $205.17M | +4321.77% |
| PLRX | Pliant Therapeutics Inc | $202.60M | +4266.29% |
| CADL | Candel Therapeutics Inc | $201.92M | +4251.72% |
| TIL | Instil Bio Inc | $200.43M | +4219.57% |
| CBIO | N/A | $199.13M | +4191.59% |
| ACRS | Aclaris Therapeutics Inc | $198.72M | +4182.76% |
| ABEO | Abeona Therapeutics Inc | $198.49M | +4177.89% |
| MGX | Metagenomi Inc | $196.95M | +4144.68% |
| ABSI | Absci Corp | $195.59M | +4115.37% |
| MIST | Milestone Pharmaceuticals Inc | $193.73M | +4075.30% |
| PBYI | Puma Biotechnology Inc | $192.70M | +4053.00% |
| TARA | Protara Therapeutics Inc | $191.92M | +4036.27% |
| IMUX | Immunic Inc | $189.74M | +3989.27% |
| BNTC | Benitec Biopharma Inc | $187.00M | +3930.17% |
| AGEN | Agenus Inc | $186.46M | +3918.45% |
| INBX | Inhibrx Biosciences Inc | $183.97M | +3864.81% |
| KRRO | Korro Bio Inc | $183.62M | +3857.37% |
| VXRT | Vaxart Inc | $180.06M | +3780.50% |
| NBY | Stablecoin Development Corp | $179.74M | +3773.77% |
| TRVI | Trevi Therapeutics Inc | $179.61M | +3770.82% |
| IVA | Inventiva | $178.52M | +3747.37% |
| ALXO | Alx Oncology Holdings Inc | $178.33M | +3743.28% |
| NAUT | Nautilus Biotechnology Inc | $177.78M | +3731.44% |
| HLVX | HilleVax Inc | $174.91M | +3669.70% |
| IKT | Inhibikase Therapeutics Inc | $173.33M | +3635.61% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $172.19M | +3610.94% |
| AURA | Aura Biosciences Inc | $169.43M | +3551.51% |
| ACET | Adicet Bio Inc | $169.38M | +3550.47% |
| RAPT | RAPT Therapeutics Inc | $165.74M | +3471.96% |
| XLO | Xilio Therapeutics Inc | $163.49M | +3423.43% |
| GYRE | Gyre Therapeutics Inc | $162.01M | +3391.70% |
| RNAZ | TransCode Therapeutics Inc | $157.16M | +3287.17% |
| CGEN | Compugen Ltd | $156.57M | +3274.35% |
| PEPG | PepGen Inc | $156.29M | +3268.43% |
| NMRA | Neumora Therapeutics Inc | $153.88M | +3216.31% |
| CLYM | Eliem Therapeutics Inc | $152.37M | +3183.88% |
| EDIT | Editas Medicine Inc | $149.34M | +3118.49% |
| CRBU | Caribou Biosciences Inc | $149.00M | +3111.16% |
| CABA | Cabaletta Bio Inc | $148.15M | +3092.80% |
| IMMP | Immutep Ltd | $147.20M | +3072.45% |
| ELDN | Eledon Pharmaceuticals Inc | $146.67M | +3060.93% |
| CMRX | Chimerix Inc | $146.01M | +3046.72% |
| OPT | Opthea Ltd | $145.77M | +3041.59% |
| PTHS | Channel Therapeutics Corporation | $145.38M | +3033.15% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $144.48M | +3013.79% |
| DTIL | Precision Biosciences Inc | $143.89M | +3001.10% |
| BOLD | Boundless Bio Inc | $140.97M | +2938.15% |
| XBIT | XBiotech Inc | $139.84M | +2913.71% |
| PGEN | Precigen Inc | $138.63M | +2887.65% |
| MNPR | Monopar Therapeutics Inc | $137.98M | +2873.79% |
| ACIU | AC Immune SA | $137.42M | +2861.66% |
| IMA | Ikena Oncology Inc | $136.68M | +2845.73% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $135.37M | +2817.46% |
| TNYA | Tenaya Therapeutics Inc | $135.07M | +2810.99% |
| ABOS | Acumen Pharmaceuticals Inc | $133.63M | +2779.94% |
| PALI | Palisade Bio Inc | $133.31M | +2773.17% |
| AVXL | Anavex Life Sciences Corporation | $132.99M | +2766.14% |
| BDTX | Black Diamond Therapeutics Inc | $132.92M | +2764.70% |
| CTXR | Citius Pharmaceuticals Inc | $132.54M | +2756.48% |
| KPTI | Karyopharm Therapeutics Inc | $131.42M | +2732.26% |
| ARTV | Artiva Biotherapeutics Inc | $130.94M | +2721.98% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $130.63M | +2715.37% |
| CDXS | Codexis Inc | $129.37M | +2688.15% |
| GOSS | Gossamer Bio Inc | $128.90M | +2678.00% |
| WHWK | Whitehawk Therapeutics Inc | $127.23M | +2642.05% |
| RPTX | Repare Therapeutics Inc | $126.75M | +2631.62% |
| RZLT | Rezolute Inc | $125.46M | +2603.86% |
| TENX | Tenax Therapeutics Inc | $123.18M | +2554.70% |
| GBIO | Generation Bio Company | $121.90M | +2527.07% |
| SRZN | Surrozen Inc | $120.71M | +2501.49% |
| PRLD | Prelude Therapeutics Inc | $119.64M | +2478.49% |
| MCRB | Seres Therapeutics Inc | $117.62M | +2434.87% |
| YMAB | Y-Mabs Therapeutics Inc | $117.21M | +2426.10% |
| SGMT | Sagimet Biosciences Inc - Class A | $116.48M | +2410.39% |
| AVTX | Avalo Therapeutics Inc | $116.46M | +2409.87% |
| SLN | Silence Therapeutics Plc | $115.12M | +2381.10% |
| NAGE | Niagen Bioscience Inc | $114.33M | +2363.99% |
| SLS | SELLAS Life Sciences Group Inc | $114.18M | +2360.71% |
| HUMA | Humacyte Inc | $110.56M | +2282.69% |
| EPIX | Essa Pharma Inc | $110.50M | +2281.51% |
| KLRS | Kalaris Therapeutics Inc | $109.81M | +2266.49% |
| FGEN | FibroGen Inc | $109.63M | +2262.69% |
| LCTX | Lineage Cell Therapeutics Inc | $109.53M | +2260.63% |
| SAVA | Cassava Sciences Inc. | $108.37M | +2235.50% |
| ACRV | Acrivon Therapeutics Inc | $107.83M | +2223.97% |
| CELU | Celularity Inc - Class A | $107.33M | +2213.13% |
| DRTS | Alpha Tau Medical Ltd | $105.65M | +2176.98% |
| CAMP | CAMP4 Therapeutics Corp | $105.46M | +2172.78% |
| PLX | Protalix BioTherapeutics Inc | $102.34M | +2105.52% |
| STTK | Shattuck Labs Inc | $102.12M | +2100.88% |
| OBIO | Orchestra BioMed Holdings Inc | $100.66M | +2069.35% |
| VTVT | vTv Therapeutics Inc - Class A | $99.49M | +2044.27% |
| GUTS | Fractyl Health Inc | $99.39M | +2041.92% |
| PRQR | ProQR Therapeutics N.V | $99.14M | +2036.58% |
| AARD | Aardvark Therapeutics Inc | $98.59M | +2024.78% |
| PMVP | PMV Pharmaceuticals Inc | $96.56M | +1981.08% |
| IMMX | Immix Biopharma Inc | $95.82M | +1965.00% |
| DWTX | Virios Therapeutics Inc | $95.21M | +1951.89% |
| NERV | Minerva Neurosciences Inc | $94.03M | +1926.45% |
| BRNS | Barinthus Biotherapeutics Plc. | $92.14M | +1885.84% |
| ANTX | AN2 Therapeutics Inc | $87.49M | +1785.58% |
| MOLN | Molecular Partners AG | $87.40M | +1783.54% |
| EPRX | Eupraxia Pharmaceuticals Inc | $86.15M | +1756.68% |
| IBIO | iBio Inc | $85.83M | +1749.87% |
| FBRX | Forte Biosciences Inc | $82.78M | +1684.03% |
| MDWD | MediWound Ltd | $79.98M | +1623.75% |
| ATYR | Atyr Pharma Inc | $79.65M | +1616.68% |
| ADAG | Adagene Inc | $78.26M | +1586.71% |
| ADVM | Adverum Biotechnologies Inc | $72.40M | +1460.37% |
| FENC | Fennec Pharmaceuticals Inc | $71.82M | +1447.89% |
| ATHA | Athira Pharma Inc | $71.59M | +1442.89% |
| HYPD | Eyenovia Inc | $70.07M | +1410.04% |
| ARMP | Armata Pharmaceuticals Inc | $69.80M | +1404.31% |
| ACOG | Alpha Cognition Inc | $69.25M | +1392.42% |
| KZR | Kezar Life Sciences Inc | $68.00M | +1365.50% |
| NBTX | Nanobiotix | $67.76M | +1360.34% |
| PMN | ProMIS Neurosciences Inc | $67.41M | +1352.84% |
| IRD | Ocuphire Pharma Inc | $66.79M | +1339.38% |
| GRCE | Acasti Pharma Inc | $66.65M | +1336.51% |
| ALDX | Aldeyra Therapeutics Inc | $66.48M | +1332.83% |
| MURA | Mural Oncology plc | $65.76M | +1317.20% |
| ALGS | Aligos Therapeutics Inc | $64.56M | +1291.34% |
| UNCY | Unicycive Therapeutics Inc | $64.41M | +1288.06% |
| PYXS | Pyxis Oncology Inc | $64.30M | +1285.78% |
| QTTB | Q32 Bio Inc | $63.67M | +1272.31% |
| EQ | Equillium Inc | $63.08M | +1259.55% |
| IPHA | Innate Pharma | $62.69M | +1251.13% |
| MRSN | Mersana Therapeutics Inc | $62.69M | +1250.99% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $62.12M | +1238.73% |
| HOOK | Hookipa Pharma Inc | $61.26M | +1220.17% |
| CNTB | Connect Biopharma Holdings Ltd | $60.07M | +1194.53% |
| SGMO | Sangamo Therapeutics Inc | $59.97M | +1192.35% |
| KLTO | Klotho Neurosciences Inc Com | $59.74M | +1187.44% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $59.74M | +1187.44% |
| SPRO | Spero Therapeutics Inc | $59.02M | +1172.00% |
| CNTX | Context Therapeutics Inc | $58.86M | +1168.51% |
| HOWL | Werewolf Therapeutics Inc | $58.02M | +1150.47% |
| LITS | Lite Strategy Inc | $57.79M | +1145.45% |
| OCGN | Ocugen Inc | $56.91M | +1126.40% |
| ATHE | Alterity Therapeutics Ltd | $56.86M | +1125.48% |
| KTTA | Pasithea Therapeutics Corp | $56.35M | +1114.55% |
| SPRB | Spruce Biosciences Inc | $56.17M | +1110.47% |
| PMCB | PharmaCyte Biotech Inc | $55.87M | +1104.17% |
| RLYB | Rallybio Corp | $54.47M | +1073.97% |
| COYA | Coya Therapeutics Inc | $53.27M | +1048.08% |
| DMAC | DiaMedica Therapeutics Inc | $53.08M | +1043.97% |
| LVTX | LAVA Therapeutics NV | $51.91M | +1018.86% |
| RANI | Rani Therapeutics Holdings Inc Class A | $51.88M | +1018.08% |
| PHXM | PHAXIAM Therapeutics SA ADR | $51.31M | +1005.75% |
| INO | Inovio Pharmaceuticals Inc | $49.78M | +972.78% |
| JAGX | Jaguar Health Inc | $49.47M | +966.21% |
| CRDF | Cardiff Oncology Inc | $49.17M | +959.74% |
| IFRX | InflaRx N.V. | $48.94M | +954.76% |
| VTGN | VistaGen Therapeutics Inc | $48.56M | +946.64% |
| BOLT | Bolt Biotherapeutics Inc | $48.03M | +935.06% |
| GRDX | Entero Therapeutics Inc | $47.97M | +933.74% |
| APRE | Aprea Therapeutics Inc | $47.61M | +926.13% |
| BMEA | Biomea Fusion Inc | $46.38M | +899.68% |
| ATNM | Actinium Pharmaceuticals Inc | $45.44M | +879.27% |
| AKTX | Akari Therapeutics Plc | $45.38M | +877.93% |
| ICCC | Immucell Corp | $44.11M | +850.61% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $43.47M | +836.86% |
| VERU | Veru Inc | $43.08M | +828.51% |
| MNOV | Medicinova Inc | $42.70M | +820.36% |
| VANI | Vivani Medical Inc | $42.35M | +812.78% |
| ACHV | Achieve Life Sciences Inc | $41.79M | +800.65% |
| MREO | Mereo Biopharma Group Plc | $40.61M | +775.30% |
| IOBT | IO Biotech Inc | $39.96M | +761.12% |
| BLRX | Bioline Rx Ltd | $38.80M | +736.14% |
| VRCA | Verrica Pharmaceuticals Inc | $38.79M | +735.91% |
| TOVX | Theriva Biologics Inc | $38.25M | +724.31% |
| SNTI | Senti Biosciences Inc | $38.24M | +724.16% |
| NXTC | Nextcure Inc | $37.98M | +718.47% |
| ATOS | Atossa Therapeutics Inc | $37.94M | +717.74% |
| PASG | Passage Bio Inc | $36.46M | +685.82% |
| CGTX | Cognition Therapeutics Inc | $36.14M | +678.88% |
| LYRA | Lyra Therapeutics Inc | $36.11M | +678.19% |
| MAIA | MAIA Biotechnology Inc | $35.32M | +661.26% |
| ALLR | Allarity Therapeutics Inc | $34.92M | +652.65% |
| NEUP | Neuphoria Therapeutics Inc | $34.81M | +650.20% |
| APLT | Applied Therapeutics Inc | $34.37M | +640.82% |
| ITRM | Iterum Therapeutics Plc | $32.50M | +600.50% |
| GNLX | Genelux Corp | $32.37M | +597.67% |
| GNTA | Genenta Science SpA | $31.89M | +587.27% |
| CUE | Cue Biopharma Inc | $30.88M | +565.45% |
| CING | Cingulate Inc | $30.86M | +565.12% |
| SLGL | Sol-Gel Technologies Ltd | $29.92M | +544.76% |
| HURA | TuHURA Biosciences Inc | $29.70M | +540.19% |
| CRIS | Curis Inc | $29.69M | +539.78% |
| CSBR | Champions Oncology Inc | $28.45M | +513.08% |
| DARE | Dare Bioscience Inc | $27.83M | +499.75% |
| NCNA | NuCana plc | $27.55M | +493.84% |
| HCWB | HCW Biologics Inc | $27.34M | +489.27% |
| SER | AgeX Therapeutics Inc | $27.30M | +488.34% |
| BCTX | BriaCell Therapeutics Corp - New | $27.07M | +483.43% |
| QNCX | Quince Therapeutics Inc | $26.62M | +473.77% |
| INAB | IN8bio Inc | $26.27M | +466.06% |
| PLUR | Pluri Inc | $26.06M | +461.57% |
| VYNE | VYNE Therapeutics Inc | $25.87M | +457.61% |
| INMB | INmune Bio Inc | $25.82M | +456.42% |
| TVRD | Cara Therapeutics Inc | $25.82M | +456.40% |
| CASI | CASI Pharmaceuticals Inc | $25.65M | +452.80% |
| NVCT | Nuvectis Pharma Inc | $25.40M | +447.37% |
| LPCN | Lipocine Inc | $25.36M | +446.51% |
| PDSB | PDS Biotechnology Corporation | $24.66M | +431.53% |
| RNTX | Rein Therapeutics Inc | $24.16M | +420.65% |
| EVAX | Evaxion Biotech A/S | $23.64M | +409.53% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $23.56M | +407.75% |
| MBRX | Moleculin Biotech Inc | $23.36M | +403.51% |
| HYFT | MindWalk Holdings Corp | $23.17M | +399.28% |
| CVM | Cel-Sci Corp | $22.89M | +393.42% |
| ELTX | Elicio Therapeutics Inc | $22.69M | +388.99% |
| PYPD | Polypid Ltd | $22.31M | +380.75% |
| OTLK | Outlook Therapeutics Inc | $21.89M | +371.82% |
| PLRZ | Polyrizon Ltd | $21.44M | +362.00% |
| KPRX | Kiora Pharmaceuticals Inc | $21.23M | +357.48% |
| LGVN | Longeveron Inc - Class A | $21.21M | +357.11% |
| JSPR | Jasper Therapeutics Inc | $21.18M | +356.55% |
| MENS | Jyong Biotech Ltd | $20.78M | +347.80% |
| GNPX | Genprex Inc | $20.31M | +337.64% |
| LPTX | Leap Therapeutics Inc | $20.04M | +331.94% |
| ATRA | Atara Biotherapeutics Inc | $20.00M | +330.97% |
| PSTV | Plus Therapeutics Inc | $19.92M | +329.22% |
| APVO | Aptevo Therapeutics Inc | $19.90M | +328.92% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $19.79M | +326.44% |
| ABVC | ABVC BioPharma Inc | $19.73M | +325.27% |
| SKYE | Skye Bioscience Inc | $19.42M | +318.46% |
| GANX | Gain Therapeutics Inc | $18.74M | +303.85% |
| APM | Aptorum Group Limited Class A Ordinary Shares | $18.69M | +302.83% |
| TTRX | Turn Therapeutics Inc | $18.64M | +301.81% |
| GLMD | Galmed Pharmaceuticals Ltd | $18.63M | +301.44% |
| BYSI | BeyondSpring Inc | $18.41M | +296.68% |
| BDRX | Biodexa Pharmaceuticals Plc | $18.15M | +291.10% |
| EVGN | Evogene Ltd | $17.95M | +286.81% |
| BIVI | BioVie Inc - Class A | $17.51M | +277.47% |
| MRKR | Marker Therapeutics Inc | $17.43M | +275.73% |
| PHIO | Phio Pharmaceuticals Corp | $17.41M | +275.26% |
| IBO | Impact BioMedical Inc | $17.09M | +268.23% |
| MBIO | Mustang Bio Inc | $16.58M | +257.37% |
| ANVS | Annovis Bio Inc | $16.24M | +250.08% |
| GALT | Galectin Therapeutics Inc | $15.76M | +239.63% |
| QNRX | Quoin Pharmaceuticals Ltd | $15.69M | +238.21% |
| ONCT | Oncternal Therapeutics Inc | $15.60M | +236.23% |
| IMRN | Immuron Ltd | $15.12M | +225.92% |
| CRVO | CervoMed Inc | $15.11M | +225.71% |
| PPCB | Propanc Biopharma Inc | $15.11M | +225.68% |
| REVB | Revelation Biosciences Inc | $15.04M | +224.23% |
| CLRB | Cellectar Biosciences Inc | $14.98M | +222.81% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $14.98M | +222.74% |
| ELAB | PMGC Holdings Inc | $14.94M | +221.94% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $14.88M | +220.79% |
| ANIX | Anixa Biosciences Inc | $14.87M | +220.37% |
| ONCO | Onconetix Inc | $14.83M | +219.66% |
| SYBX | Synlogic Inc | $14.61M | +214.89% |
| CMND | Clearmind Medicine Inc | $14.52M | +213.01% |
| MTVA | MetaVia Inc | $14.39M | +210.09% |
| LSTA | Lisata Therapeutics Inc | $14.06M | +203.00% |
| RNXT | RenovoRx Inc | $13.96M | +200.95% |
| ADTX | Aditxt Inc | $13.91M | +199.72% |
| CMMB | Chemomab Therapeutics Ltd | $13.81M | +197.67% |
| YDES | YD Bio Ltd | $13.78M | +196.97% |
| PTN | Palatin Technologies Inc | $13.23M | +185.03% |
| ENTX | Entera Bio Ltd | $13.13M | +182.95% |
| PBM | Psyence Biomedical Ltd | $12.81M | +176.08% |
| XCUR | Exicure Inc | $12.76M | +174.89% |
| ARTL | Artelo Biosciences Inc | $12.52M | +169.78% |
| EDSA | Edesa Biotech Inc | $12.38M | +166.91% |
| KALA | Kala Bio Inc | $12.32M | +165.47% |
| INTS | Intensity Therapeutics Inc | $12.29M | +164.89% |
| AZTR | Azitra Inc | $12.13M | +161.35% |
| NRXP | NRX Pharmaceuticals Inc | $11.90M | +156.53% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $11.64M | +150.88% |
| SCNI | Scinai Immunotherapeutics Ltd | $11.63M | +150.56% |
| NCEL | NLS Pharmaceutics Ltd | $11.45M | +146.66% |
| GRI | GRI Bio Inc | $11.34M | +144.38% |
| ICU | SeaStar Medical Holding Corp | $11.26M | +142.74% |
| TPST | Tempest Therapeutics Inc | $10.75M | +131.64% |
| ERNA | Ernexa Therapeutics Inc | $10.54M | +127.22% |
| GLSI | Greenwich LifeSciences Inc | $10.51M | +126.41% |
| INKT | MiNK Therapeutics Inc | $10.38M | +123.64% |
| NNVC | NanoViricides Inc | $10.22M | +120.24% |
| HIND | ReShape Lifesciences Inc | $10.19M | +119.51% |
| LNAI | Lunai Bioworks Inc | $9.86M | +112.51% |
| CLDI | Calidi Biotherapeutics Inc | $9.59M | +106.70% |
| CDIO | Cardio Diagnostics Holdings Inc | $9.56M | +106.02% |
| ACXP | Acurx Pharmaceuticals Inc | $9.54M | +105.60% |
| CANF | Can-Fite Biopharma Ltd | $9.51M | +105.04% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $9.42M | +103.06% |
| IGC | IGC Pharma Inc | $9.19M | +97.95% |
| CLGN | CollPlant Biotechnologies Ltd New | $9.18M | +97.91% |
| ACTU | Actuate Therapeutics Inc | $8.91M | +92.05% |
| NRXS | Neuraxis Inc | $8.75M | +88.49% |
| AEON | AEON Biopharma Inc - Class A | $8.63M | +85.99% |
| CALC | CalciMedica Inc | $8.61M | +85.54% |
| AIM | AIM ImmunoTech Inc. | $8.59M | +85.02% |
| BCAB | BioAtla Inc | $8.57M | +84.61% |
| CDT | CDT Equity Inc | $8.55M | +84.31% |
| CYCN | Cyclerion Therapeutics Inc | $8.51M | +83.30% |
| SLRX | Decoy Therapeutics Inc | $8.42M | +81.54% |
| CURX | Curanex Pharmaceuticals Inc | $8.41M | +81.28% |
| ONCY | Oncolytics Biotech Inc | $8.16M | +75.88% |
| TRAW | Traws Pharma Inc | $8.16M | +75.78% |
| IMNN | Imunon Inc | $8.02M | +72.82% |
| GDTC | CytoMed Therapeutics Ltd | $7.98M | +72.09% |
| XBIO | Xenetic Biosciences Inc | $7.91M | +70.45% |
| DYAI | Dyadic International Inc DE | $7.81M | +68.31% |
| BGMS | Bio Green Med Solution Inc | $7.56M | +63.02% |
| OGEN | Oragenics Inc | $7.49M | +61.41% |
| DRMA | Dermata Therapeutics Inc | $7.47M | +60.90% |
| COCP | Cocrystal Pharma Inc | $7.43M | +60.04% |
| VIVS | VivoSim Labs Inc | $7.39M | +59.18% |
| TELO | Telomir Pharmaceuticals Inc | $7.34M | +58.22% |
| OSTX | OS Therapies Inc | $7.30M | +57.31% |
| LTRN | Lantern Pharma Inc | $7.22M | +55.67% |
| ASBP | Aspire Biopharma Holdings Inc | $7.12M | +53.39% |
| SILO | SILO Pharma Inc | $7.02M | +51.25% |
| SNGX | Soligenix Inc | $6.92M | +49.19% |
| NTRB | Nutriband Inc | $6.89M | +48.54% |
| INDP | Indaptus Therapeutics Inc | $6.84M | +47.41% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $6.76M | +45.76% |
| GTBP | GT Biopharma Inc | $6.76M | +45.67% |
| APLM | Apollomics Inc - Class A | $6.71M | +44.70% |
| CELZ | Creative Medical Technology Holdings Inc | $6.44M | +38.81% |
| FBLG | FibroBiologics Inc | $5.94M | +27.97% |
| MTNB | Matinas Biopharma Holdings Inc | $5.87M | +26.59% |
| KAPA | Kairos Pharma Ltd | $5.74M | +23.79% |
| VRAX | Virax Biolabs Group Ltd - Class A | $5.72M | +23.17% |
| HOTH | Hoth Therapeutics Inc | $5.59M | +20.56% |
| ENVB | Enveric Biosciences Inc | $5.52M | +19.00% |
| ADIL | Adial Pharmaceuticals Inc | $5.23M | +12.66% |
| BBLG | Bone Biologics Corp | $4.98M | +7.31% |
| TVGN | Tevogen Bio Holdings Inc | $4.92M | +6.06% |
| LEXX | Lexaria Bioscience Corp | $4.78M | +3.05% |
| ADXN | Addex Therapeutics Ltd | $4.76M | +2.57% |
| CNSP | Cns Pharmaceuticals Inc | $4.65M | +0.28% |
| OKYO | OKYO Pharma Ltd - New | $4.64M | +0.08% |
| SLXN | Silexion Therapeutics Corp | $4.60M | -0.82% |
| PCSA | Processa Pharmaceuticals Inc | $4.52M | -2.57% |
| PULM | Pulmatrix Inc | $4.50M | -3.10% |
| PTIX | Protagenic Therapeutics Inc | $4.43M | -4.50% |
| ALZN | Alzamend Neuro Inc | $4.04M | -12.89% |
| EXOZ | Invizyne Technologies Inc | $4.02M | -13.39% |
| JUNS | Jupiter Neurosciences Inc | $3.95M | -14.90% |
| ESLA | Estrella Immunopharma Inc | $3.66M | -21.18% |
| NTHI | NeOnc Technologies Holdings Inc | $3.33M | -28.23% |
| TTNP | Titan Pharmaceuticals Inc (de) | $3.05M | -34.25% |
| GOVX | Geovax Labs Inc | $2.98M | -35.72% |
| CVKD | Cadrenal Therapeutics Inc | $2.86M | -38.32% |
| LIMN | Liminatus Pharma Inc | $2.79M | -39.87% |
| ENSC | Ensysce Biosciences Inc | $2.17M | -53.28% |
| XRTX | XORTX Therapeutics Inc | $2.15M | -53.62% |
| TCRT | Alaunos Therapeutics Inc | $1.88M | -59.42% |
| BCDA | BioCardia Inc | $1.71M | -63.10% |
| ABP | Abpro Holdings, Inc Common Stock | $1.06M | -77.09% |
| NRSN | NeuroSense Therapeutics Ltd | $1.03M | -77.84% |
| BCLI | Brainstorm Cell Therapeutics Inc | $755000.00 | -83.73% |
| ZVSA | ZyVersa Therapeutics Inc | $742223.00 | -84.00% |