| REGN | Regeneron Pharmaceuticals Inc | $40.87B | +336823.33% |
| VRTX | Vertex Pharmaceuticals Inc | $26.48B | +218238.00% |
| BNTX | BioNTech SE | $21.10B | +173816.55% |
| RPRX | Royalty Pharma plc - Class A | $19.82B | +163258.74% |
| GMAB | Genmab | $12.38B | +101926.38% |
| JAZZ | Jazz Pharmaceuticals plc | $11.86B | +97670.82% |
| MRNA | Moderna Inc | $11.49B | +94607.34% |
| ARGX | Argen X SE | $8.68B | +71480.36% |
| BMRN | Biomarin Pharmaceutical Inc | $8.59B | +70724.53% |
| ONC | BeiGene Ltd | $8.55B | +70416.23% |
| SVA | Sinovac Biotech Ltd | $8.54B | +70318.18% |
| INCY | Incyte Corp | $7.34B | +60403.82% |
| ROIV | Roivant Sciences Ltd | $5.71B | +46962.55% |
| ALNY | Alnylam Pharmaceuticals Inc | $4.97B | +40842.55% |
| AAPG | Ascentage Pharma Group International | $3.97B | +32596.63% |
| IONS | Ionis Pharmaceuticals Inc | $3.45B | +28341.62% |
| GLPG | Galapagos NV | $3.41B | +27971.46% |
| PCVX | Vaxcyte Inc | $3.35B | +27503.53% |
| SRPT | Sarepta Therapeutics Inc | $3.18B | +26107.21% |
| PTCT | PTC Therapeutics Inc | $2.87B | +23552.96% |
| CRSP | CRISPR Therapeutics AG | $2.73B | +22371.72% |
| FTRE | Fortrea Holdings Inc | $2.68B | +22022.01% |
| HALO | Halozyme Therapeutics Inc | $2.67B | +21933.96% |
| NBP | NovaBridge Biosciences. | $2.61B | +21441.36% |
| EXEL | Exelixis Inc | $2.59B | +21281.64% |
| TECH | Bio-Techne Corp | $2.55B | +20927.21% |
| ENLV | Enlivex Ltd | $2.33B | +19083.83% |
| ARWR | Arrowhead Pharmaceuticals Inc | $2.27B | +18599.63% |
| RVMD | Revolution Medicines Inc | $2.25B | +18479.86% |
| INSM | Insmed Inc | $2.08B | +17013.46% |
| ASND | Ascendis Pharma A/S | $2.01B | +16432.30% |
| INVA | Innoviva Inc | $1.84B | +15040.87% |
| TLX | Telix Pharmaceuticals Ltd | $1.77B | +14499.46% |
| KYMR | Kymera Therapeutics Inc | $1.67B | +13659.41% |
| ACAD | Acadia Pharmaceuticals Inc | $1.61B | +13133.55% |
| LEGN | Legend Biotech Corp | $1.60B | +13063.64% |
| LGND | Ligand Pharmaceuticals Inc - Class B | $1.53B | +12530.71% |
| TGTX | TG Therapeutics Inc | $1.53B | +12503.77% |
| GPCR | Structure Therapeutics Inc | $1.51B | +12333.01% |
| BEAM | Beam Therapeutics Inc | $1.48B | +12107.73% |
| PRAX | Praxis Precision Medicines Inc | $1.46B | +11937.94% |
| CRNX | Crinetics Pharmaceuticals Inc | $1.40B | +11452.54% |
| KRYS | Krystal Biotech Inc | $1.40B | +11416.63% |
| XENE | Xenon Pharmaceuticals Inc | $1.39B | +11332.89% |
| BBIO | BridgeBio Pharma Inc | $1.37B | +11202.40% |
| RXRX | Recursion Pharmaceuticals Inc - Class A | $1.34B | +10943.05% |
| NUVL | Nuvalent Inc - Class A | $1.33B | +10874.01% |
| ABCL | AbCellera Biologics Inc | $1.31B | +10675.86% |
| RARE | Ultragenyx Pharmaceutical Inc | $1.30B | +10584.25% |
| APGE | Apogee Therapeutics Inc | $1.29B | +10564.91% |
| CYTK | Cytokinetics Inc | $1.27B | +10398.58% |
| HRMY | Harmony Biosciences Holdings Inc | $1.27B | +10384.95% |
| DNLI | Denali Therapeutics Inc | $1.27B | +10337.12% |
| DNTH | Dianthus Therapeutics Inc | $1.25B | +10179.34% |
| MDGL | Madrigal Pharmaceuticals Inc | $1.23B | +10018.11% |
| AGIO | Agios Pharmaceuticals Inc | $1.18B | +9669.08% |
| CAI | Caris Life Sciences Inc - Class A | $1.16B | +9482.75% |
| CPRX | Catalyst Pharmaceuticals Inc | $1.15B | +9360.92% |
| CVAC | CureVac N.V. | $1.14B | +9286.80% |
| CGON | Cg Oncology Inc | $1.14B | +9259.13% |
| ZLAB | Zai Lab Ltd | $1.10B | +8933.28% |
| APLS | Apellis Pharmaceuticals Inc | $1.08B | +8824.42% |
| DYN | Dyne Therapeutics Inc | $1.08B | +8803.13% |
| IMCR | Immunocore Holdings plc | $1.07B | +8738.38% |
| NVAX | Novavax Inc | $1.04B | +8499.85% |
| DNA | Ginkgo Bioworks Holdings Inc - Class A | $1.03B | +8416.69% |
| IDYA | Ideaya Biosciences Inc | $1.03B | +8394.21% |
| JANX | Janux Therapeutics Inc | $1.03B | +8376.71% |
| VIR | Vir Biotechnology Inc | $1.03B | +8354.95% |
| TERN | Terns Pharmaceuticals Inc | $1.03B | +8350.77% |
| AKRO | Akero Therapeutics Inc | $1.01B | +8190.00% |
| RCUS | Arcus Biosciences Inc | $997.00M | +8119.29% |
| IMVT | Immunovant Inc | $957.01M | +7789.65% |
| FOLD | Amicus Therapeutics Inc | $949.87M | +7730.75% |
| IOVA | Iovance Biotherapeutics Inc | $925.66M | +7531.20% |
| MRUS | Merus N.V | $904.20M | +7354.21% |
| COGT | Cogent Biosciences Inc | $903.01M | +7344.40% |
| MIRM | Mirum Pharmaceuticals Inc | $890.92M | +7244.73% |
| MRVI | Maravai LifeSciences Holdings Inc - Class A | $849.19M | +6900.75% |
| CRMD | CorMedix Inc | $815.64M | +6624.13% |
| CORT | Corcept Therapeutics Inc | $814.88M | +6617.90% |
| VRDN | Viridian Therapeutics Inc | $789.02M | +6404.67% |
| MESO | Mesoblast Ltd | $782.31M | +6349.36% |
| BLTE | Belite Bio Inc | $780.56M | +6334.92% |
| QURE | uniQure N.V. | $778.71M | +6319.67% |
| SYRE | Spyre Therapeutics Inc | $763.95M | +6198.05% |
| NKTR | Nektar Therapeutics | $763.27M | +6192.42% |
| NTLA | Intellia Therapeutics Inc | $758.78M | +6155.39% |
| IRON | Disc Medicine Inc | $750.21M | +6084.77% |
| ZBIO | Zenas Biopharma Inc | $747.68M | +6063.91% |
| MNKD | Mannkind Corp | $744.40M | +6036.88% |
| XNCR | Xencor Inc | $736.85M | +5974.58% |
| GLUE | Monte Rosa Therapeutics Inc | $736.43M | +5971.13% |
| NAMS | NewAmsterdam Pharma Company NV | $732.64M | +5939.93% |
| OCUL | Ocular Therapeutix Inc | $732.53M | +5938.99% |
| AUPH | Aurinia Pharmaceuticals Inc | $724.00M | +5868.65% |
| RLAY | Relay Therapeutics Inc | $699.61M | +5667.63% |
| PTGX | Protagonist Therapeutics Inc | $697.46M | +5649.87% |
| ALMS | Alumis Inc | $671.59M | +5436.59% |
| ADMA | Adma Biologics Inc | $665.18M | +5383.79% |
| MLYS | Mineralys Therapeutics Inc | $652.86M | +5282.21% |
| KURA | Kura Oncology Inc | $652.55M | +5279.65% |
| BCYC | Bicycle Therapeutics Plc | $652.40M | +5278.37% |
| SMMT | Summit Therapeutics Inc | $647.86M | +5240.94% |
| ARVN | Arvinas Inc | $647.50M | +5238.00% |
| IBRX | ImmunityBio Inc | $646.64M | +5230.89% |
| CNTA | Centessa Pharmaceuticals plc | $641.76M | +5190.71% |
| VERA | Vera Therapeutics Inc - Class A | $621.74M | +5025.63% |
| IMNM | Immunome Inc | $619.79M | +5009.58% |
| NUVB | Nuvation Bio Inc - Class A | $610.24M | +4930.84% |
| SLNO | Soleno Therapeutics Inc | $608.39M | +4915.56% |
| VKTX | Viking Therapeutics Inc | $608.24M | +4914.36% |
| ACLX | Arcellx Inc | $603.99M | +4879.31% |
| THAR | Tharimmune Inc | $584.65M | +4719.91% |
| WVE | Wave Life Sciences Ltd | $583.54M | +4710.75% |
| TARS | Tarsus Pharmaceuticals Inc | $581.13M | +4690.89% |
| VRNA | Verona Pharma Plc | $572.87M | +4622.76% |
| SEPN | Septerna Inc | $569.69M | +4596.52% |
| TVTX | Travere Therapeutics Inc | $555.19M | +4476.98% |
| BCAX | Bicara Therapeutics Inc | $553.60M | +4463.88% |
| PRTC | PureTech Health plc American Depositary Shares | $553.24M | +4460.94% |
| ABVX | Abivax | $547.14M | +4410.65% |
| IMTX | Immatics N.V | $543.83M | +4383.35% |
| NRIX | Nurix Therapeutics Inc | $535.54M | +4315.00% |
| GLTO | Galecto Inc | $535.44M | +4314.20% |
| SRRK | Scholar Rock Holding Corp | $535.25M | +4312.65% |
| GERN | Geron Corp | $534.12M | +4303.30% |
| OLMA | Olema Pharmaceuticals Inc | $530.64M | +4274.65% |
| AUTL | Autolus Therapeutics plc | $527.07M | +4245.14% |
| CDTX | Cidara Therapeutics Inc | $518.65M | +4175.76% |
| EWTX | Edgewise Therapeutics Inc | $518.52M | +4174.71% |
| FDMT | 4D Molecular Therapeutics Inc | $512.90M | +4128.40% |
| CLDX | Celldex Therapeutics Inc | $511.25M | +4114.79% |
| DAWN | Day One Biopharmaceuticals Inc | $507.83M | +4086.54% |
| VOR | Vor Biopharma Inc | $506.75M | +4077.63% |
| RIGL | Rigel Pharmaceuticals | $504.61M | +4060.00% |
| ARDX | Ardelyx Inc | $504.51M | +4059.17% |
| ORKA | ARCA biopharma Inc | $504.48M | +4058.94% |
| RAPP | Rapport Therapeutics Inc | $497.60M | +4002.20% |
| PHAR | Pharming Group N.V. | $489.37M | +3934.34% |
| VCEL | Vericel Corp | $485.63M | +3903.52% |
| ZYME | Zymeworks BC Inc | $478.21M | +3842.42% |
| SNDX | Syndax Pharmaceuticals Inc | $472.67M | +3796.69% |
| TBPH | Theravance Biopharma Inc | $472.31M | +3793.76% |
| BHVN | Biohaven Ltd | $466.41M | +3745.06% |
| ELVN | Enliven Therapeutics Inc | $464.85M | +3732.25% |
| RVNC | Revance Therapeutics Inc | $461.56M | +3705.14% |
| ERAS | Erasca Inc | $461.23M | +3702.42% |
| ARQT | Arcutis Biotherapeutics Inc | $460.00M | +3692.28% |
| MBX | MBX Biosciences Inc | $452.70M | +3632.08% |
| STOK | Stoke Therapeutics Inc | $443.28M | +3554.39% |
| RYTM | Rhythm Pharmaceuticals Inc | $442.32M | +3546.46% |
| ORIC | ORIC Pharmaceuticals Inc | $436.76M | +3500.68% |
| SLRN | Acelyrin Inc | $436.50M | +3498.55% |
| TNGX | Tango Therapeutics Inc | $435.79M | +3492.68% |
| VNDA | Vanda Pharmaceuticals Inc | $433.52M | +3473.99% |
| SLDB | Solid Biosciences Inc | $422.89M | +3386.34% |
| MAZE | Maze Therapeutics Inc | $419.71M | +3360.10% |
| MPLT | MapLight Therapeutics Inc | $418.79M | +3352.50% |
| BBOT | BridgeBio Oncology Therapeutics Inc Com | $417.65M | +3343.08% |
| TYRA | Tyra Biosciences Inc | $412.04M | +3296.87% |
| CELC | Celcuity Inc | $410.16M | +3281.40% |
| CGEM | Cullinan Oncology Inc | $402.98M | +3222.21% |
| MNMD | Mind Medicine (MindMed) Inc. Common Shares | $401.29M | +3208.27% |
| MLTX | MoonLake Immunotherapeutics - Class A | $400.37M | +3200.69% |
| ALLO | Allogene Therapeutics Inc | $395.96M | +3164.29% |
| LBRX | LB Pharmaceuticals Inc | $393.48M | +3143.87% |
| SANA | Sana Biotechnology Inc | $373.59M | +2979.91% |
| VALN | Valneva SE | $372.40M | +2970.08% |
| NKTX | Nkarta Inc | $372.07M | +2967.38% |
| CTMX | CytomX Therapeutics Inc | $359.36M | +2862.56% |
| FBIO | Fortress Biotech Inc | $356.87M | +2842.08% |
| PROK | ProKidney Corp - Class A | $351.61M | +2798.66% |
| LYEL | Lyell Immunopharma Inc | $350.63M | +2790.57% |
| PRTA | Prothena Corporation plc | $349.89M | +2784.53% |
| AVBP | ArriVent BioPharma Inc | $349.30M | +2779.60% |
| FULC | Fulcrum Therapeutics Inc | $346.77M | +2758.78% |
| RGNX | Regenxbio Inc | $341.89M | +2718.58% |
| TRDA | Entrada Therapeutics Inc | $335.52M | +2666.02% |
| REPL | Replimune Group Inc | $332.39M | +2640.21% |
| ANAB | AnaptysBio Inc | $329.68M | +2617.92% |
| KALV | KalVista Pharmaceuticals Inc | $328.92M | +2611.60% |
| CCCC | C4 Therapeutics Inc | $328.86M | +2611.14% |
| IPSC | Century Therapeutics Inc | $326.55M | +2592.11% |
| CAPR | Capricor Therapeutics Inc | $326.28M | +2589.89% |
| CBUS | Cibus Global Ltd. Class A | $324.20M | +2572.73% |
| EVMN | Evommune Inc | $322.45M | +2558.33% |
| JBIO | Jade Biosciences Inc | $319.43M | +2533.41% |
| UPB | Upstream Bio Inc | $318.05M | +2522.04% |
| ENTA | Enanta Pharmaceuticals Inc | $314.70M | +2494.43% |
| KROS | Keros Therapeutics Inc | $312.29M | +2474.55% |
| DRUG | Bright Minds Biosciences Inc | $312.15M | +2473.34% |
| MDXG | Mimedx Group Inc | $308.68M | +2444.73% |
| ENGN | enGene Holdings Inc | $307.52M | +2435.23% |
| KOD | Kodiak Sciences Inc | $306.01M | +2422.72% |
| PHAT | Phathom Pharmaceuticals Inc | $305.12M | +2415.42% |
| SION | Sionna Therapeutics Inc | $305.04M | +2414.75% |
| TSHA | Taysha Gene Therapies Inc | $300.35M | +2376.10% |
| PRME | Prime Medicine Inc | $294.73M | +2329.76% |
| OABI | OmniAb Inc | $293.65M | +2320.86% |
| RNA | Atrium Therapeutics Inc | $292.36M | +2310.22% |
| CLLS | Cellectis | $289.19M | +2284.06% |
| RNAC | Cartesian Therapeutics Inc | $288.39M | +2277.50% |
| EYPT | EyePoint Pharmaceuticals Inc | $288.22M | +2276.07% |
| SPRY | ARS Pharmaceuticals Inc | $287.57M | +2270.74% |
| OMER | Omeros Corporation | $286.17M | +2259.22% |
| RCKT | Rocket Pharmaceuticals Inc | $285.41M | +2252.90% |
| FATE | Fate Therapeutics Inc | $284.92M | +2248.85% |
| ALT | Altimmune Inc | $279.93M | +2207.74% |
| THRD | Third Harmonic Bio Inc | $279.84M | +2206.97% |
| ZVRA | Zevra Therapeutics Inc | $278.58M | +2196.61% |
| ABUS | Arbutus Biopharma Corp | $277.16M | +2184.95% |
| ANRO | Alto Neuroscience Inc | $276.26M | +2177.49% |
| GHRS | GH Research PLC | $275.27M | +2169.31% |
| LENZ | LENZ Therapeutics Inc | $272.54M | +2146.78% |
| SEER | Seer Inc - Class A | $272.13M | +2143.46% |
| ATXS | Astria Therapeutics Inc | $271.87M | +2141.27% |
| XOMA | XOMA Royalty Corp | $271.86M | +2141.20% |
| XFOR | X4 Pharmaceuticals Inc | $270.28M | +2128.20% |
| TRML | Tourmaline Bio Inc | $269.30M | +2120.07% |
| ORMP | Oramed Pharmaceuticals Inc | $268.85M | +2116.38% |
| LXRX | Lexicon Pharmaceuticals Inc | $268.82M | +2116.15% |
| AVIR | Atea Pharmaceuticals Inc | $267.08M | +2101.78% |
| DBVT | DBV Technologies | $266.40M | +2096.21% |
| CHRS | Coherus Biosciences Inc | $266.02M | +2093.09% |
| ATAI | ATAI Life Sciences N.V. | $264.88M | +2083.65% |
| PVLA | Palvella Therapeutics Inc | $263.76M | +2074.44% |
| NGNE | Neoleukin Therapeutics Inc | $263.14M | +2069.34% |
| ANNX | Annexon Inc | $262.89M | +2067.25% |
| TCRX | Tscan Therapeutics Inc | $262.23M | +2061.79% |
| CTNM | Contineum Therapeutics Inc - Class A | $261.35M | +2054.57% |
| PHVS | Pharvaris NV | $259.79M | +2041.70% |
| TNXP | Tonix Pharmaceuticals Holding Corp | $257.91M | +2026.23% |
| KYTX | Kyverna Therapeutics Inc | $257.02M | +2018.91% |
| URGN | UroGen Pharma Ltd | $253.69M | +1991.43% |
| CRVS | Corvus Pharmaceuticals Inc | $253.19M | +1987.35% |
| ZNTL | Zentalis Pharmaceuticals Inc | $253.07M | +1986.28% |
| LXEO | Lexeo Therapeutics Inc | $250.36M | +1963.94% |
| SABS | SAB Biotherapeutics Inc | $248.47M | +1948.40% |
| TECX | AvroBio Inc | $246.58M | +1932.79% |
| HRTX | Heron Therapeutics Inc | $246.22M | +1929.81% |
| ARCT | Arcturus Therapeutics Holdings Inc | $245.41M | +1923.17% |
| MGTX | MeiraGTx Holdings plc | $244.66M | +1916.94% |
| OCS | Oculis Holding AG | $243.26M | +1905.48% |
| STRO | Sutro Biopharma Inc | $241.99M | +1894.95% |
| IVVD | Invivyd Inc | $241.74M | +1892.93% |
| ALEC | Alector Inc | $239.92M | +1877.87% |
| ASMB | Assembly Biosciences Inc | $235.51M | +1841.53% |
| RLMD | Relmada Therapeutics Inc | $235.36M | +1840.34% |
| DSGN | Design Therapeutics Inc | $230.44M | +1799.77% |
| ZURA | Zura Bio Ltd - Class A | $228.64M | +1784.92% |
| VSTM | Verastem Inc | $227.81M | +1778.05% |
| OVID | Ovid Therapeutics Inc | $225.63M | +1760.08% |
| FHTX | Foghorn Therapeutics Inc | $222.17M | +1731.55% |
| SVRA | Savara Inc | $221.65M | +1727.25% |
| VYGR | Voyager Therapeutics Inc | $219.32M | +1708.12% |
| MGNX | Macrogenics Inc | $217.87M | +1696.15% |
| IMRX | Immuneering Corp Class A | $214.81M | +1670.90% |
| VTYX | Ventyx Biosciences Inc | $211.47M | +1643.32% |
| LRMR | Larimar Therapeutics Inc | $208.51M | +1618.97% |
| IMAB | I-Mab | $206.71M | +1604.11% |
| SNSE | Sensei Biotherapeutics Inc | $205.38M | +1593.17% |
| CMPX | Compass Therapeutics Inc | $205.17M | +1591.43% |
| PLRX | Pliant Therapeutics Inc | $202.60M | +1570.21% |
| CADL | Candel Therapeutics Inc | $201.92M | +1564.63% |
| TIL | Instil Bio Inc | $200.43M | +1552.33% |
| CBIO | N/A | $199.13M | +1541.63% |
| ACRS | Aclaris Therapeutics Inc | $198.72M | +1538.25% |
| ABEO | Abeona Therapeutics Inc | $198.49M | +1536.39% |
| MGX | Metagenomi Inc | $196.95M | +1523.69% |
| ABSI | Absci Corp | $195.59M | +1512.47% |
| MIST | Milestone Pharmaceuticals Inc | $193.73M | +1497.15% |
| PBYI | Puma Biotechnology Inc | $192.70M | +1488.62% |
| TARA | Protara Therapeutics Inc | $191.92M | +1482.22% |
| IMUX | Immunic Inc | $189.74M | +1464.24% |
| BNTC | Benitec Biopharma Inc | $187.00M | +1441.63% |
| AGEN | Agenus Inc | $186.46M | +1437.15% |
| INBX | Inhibrx Biosciences Inc | $183.97M | +1416.63% |
| KRRO | Korro Bio Inc | $183.62M | +1413.78% |
| VXRT | Vaxart Inc | $180.06M | +1384.38% |
| NBY | Stablecoin Development Corp | $179.74M | +1381.81% |
| TRVI | Trevi Therapeutics Inc | $179.61M | +1380.68% |
| IVA | Inventiva | $178.52M | +1371.71% |
| ALXO | Alx Oncology Holdings Inc | $178.33M | +1370.14% |
| NAUT | Nautilus Biotechnology Inc | $177.78M | +1365.61% |
| HLVX | HilleVax Inc | $174.91M | +1342.00% |
| IKT | Inhibikase Therapeutics Inc | $173.33M | +1328.95% |
| OSRH | Bellevue Life Sciences Acquisition Corp | $172.19M | +1319.52% |
| AURA | Aura Biosciences Inc | $169.43M | +1296.78% |
| ACET | Adicet Bio Inc | $169.38M | +1296.39% |
| RAPT | RAPT Therapeutics Inc | $165.74M | +1266.36% |
| XLO | Xilio Therapeutics Inc | $163.49M | +1247.79% |
| GYRE | Gyre Therapeutics Inc | $162.01M | +1235.66% |
| RNAZ | TransCode Therapeutics Inc | $157.16M | +1195.67% |
| CGEN | Compugen Ltd | $156.57M | +1190.77% |
| PEPG | PepGen Inc | $156.29M | +1188.50% |
| NMRA | Neumora Therapeutics Inc | $153.88M | +1168.57% |
| CLYM | Eliem Therapeutics Inc | $152.37M | +1156.16% |
| EDIT | Editas Medicine Inc | $149.34M | +1131.15% |
| CRBU | Caribou Biosciences Inc | $149.00M | +1128.34% |
| CABA | Cabaletta Bio Inc | $148.15M | +1121.32% |
| IMMP | Immutep Ltd | $147.20M | +1113.54% |
| ELDN | Eledon Pharmaceuticals Inc | $146.67M | +1109.13% |
| CMRX | Chimerix Inc | $146.01M | +1103.69% |
| OPT | Opthea Ltd | $145.77M | +1101.73% |
| PTHS | Channel Therapeutics Corporation | $145.38M | +1098.50% |
| CRBP | Corbus Pharmaceuticals Holdings Inc | $144.48M | +1091.10% |
| DTIL | Precision Biosciences Inc | $143.89M | +1086.24% |
| BOLD | Boundless Bio Inc | $140.97M | +1062.16% |
| XBIT | XBiotech Inc | $139.84M | +1052.81% |
| PGEN | Precigen Inc | $138.63M | +1042.84% |
| MNPR | Monopar Therapeutics Inc | $137.98M | +1037.54% |
| ACIU | AC Immune SA | $137.42M | +1032.90% |
| IMA | Ikena Oncology Inc | $136.68M | +1026.81% |
| ENTO | Entero Therapeutics, Inc. Common Stock | $135.37M | +1016.00% |
| TNYA | Tenaya Therapeutics Inc | $135.07M | +1013.52% |
| ABOS | Acumen Pharmaceuticals Inc | $133.63M | +1001.64% |
| PALI | Palisade Bio Inc | $133.31M | +999.05% |
| AVXL | Anavex Life Sciences Corporation | $132.99M | +996.36% |
| BDTX | Black Diamond Therapeutics Inc | $132.92M | +995.81% |
| CTXR | Citius Pharmaceuticals Inc | $132.54M | +992.67% |
| KPTI | Karyopharm Therapeutics Inc | $131.42M | +983.40% |
| ARTV | Artiva Biotherapeutics Inc | $130.94M | +979.47% |
| ADAP | Adaptimmune Therapeutics plc American Depositary Shares | $130.63M | +976.94% |
| CDXS | Codexis Inc | $129.37M | +966.53% |
| GOSS | Gossamer Bio Inc | $128.90M | +962.65% |
| WHWK | Whitehawk Therapeutics Inc | $127.23M | +948.90% |
| RPTX | Repare Therapeutics Inc | $126.75M | +944.91% |
| RZLT | Rezolute Inc | $125.46M | +934.29% |
| TENX | Tenax Therapeutics Inc | $123.18M | +915.48% |
| GBIO | Generation Bio Company | $121.90M | +904.91% |
| SRZN | Surrozen Inc | $120.71M | +895.13% |
| PRLD | Prelude Therapeutics Inc | $119.64M | +886.33% |
| MCRB | Seres Therapeutics Inc | $117.62M | +869.65% |
| YMAB | Y-Mabs Therapeutics Inc | $117.21M | +866.29% |
| SGMT | Sagimet Biosciences Inc - Class A | $116.48M | +860.28% |
| AVTX | Avalo Therapeutics Inc | $116.46M | +860.08% |
| SLN | Silence Therapeutics Plc | $115.12M | +849.08% |
| NAGE | Niagen Bioscience Inc | $114.33M | +842.53% |
| SLS | SELLAS Life Sciences Group Inc | $114.18M | +841.28% |
| HUMA | Humacyte Inc | $110.56M | +811.43% |
| EPIX | Essa Pharma Inc | $110.50M | +810.98% |
| KLRS | Kalaris Therapeutics Inc | $109.81M | +805.23% |
| FGEN | FibroGen Inc | $109.63M | +803.78% |
| LCTX | Lineage Cell Therapeutics Inc | $109.53M | +802.99% |
| SAVA | Cassava Sciences Inc. | $108.37M | +793.38% |
| ACRV | Acrivon Therapeutics Inc | $107.83M | +788.97% |
| CELU | Celularity Inc - Class A | $107.33M | +784.82% |
| DRTS | Alpha Tau Medical Ltd | $105.65M | +771.00% |
| CAMP | CAMP4 Therapeutics Corp | $105.46M | +769.39% |
| PLX | Protalix BioTherapeutics Inc | $102.34M | +743.66% |
| STTK | Shattuck Labs Inc | $102.12M | +741.89% |
| OBIO | Orchestra BioMed Holdings Inc | $100.66M | +729.83% |
| VTVT | vTv Therapeutics Inc - Class A | $99.49M | +720.23% |
| GUTS | Fractyl Health Inc | $99.39M | +719.33% |
| PRQR | ProQR Therapeutics N.V | $99.14M | +717.29% |
| AARD | Aardvark Therapeutics Inc | $98.59M | +712.78% |
| PMVP | PMV Pharmaceuticals Inc | $96.56M | +696.06% |
| IMMX | Immix Biopharma Inc | $95.82M | +689.91% |
| DWTX | Virios Therapeutics Inc | $95.21M | +684.90% |
| NERV | Minerva Neurosciences Inc | $94.03M | +675.16% |
| BRNS | Barinthus Biotherapeutics Plc. | $92.14M | +659.63% |
| ANTX | AN2 Therapeutics Inc | $87.49M | +621.28% |
| MOLN | Molecular Partners AG | $87.40M | +620.50% |
| EPRX | Eupraxia Pharmaceuticals Inc | $86.15M | +610.22% |
| IBIO | iBio Inc | $85.83M | +607.62% |
| FBRX | Forte Biosciences Inc | $82.78M | +582.43% |
| MDWD | MediWound Ltd | $79.98M | +559.37% |
| ATYR | Atyr Pharma Inc | $79.65M | +556.67% |
| ADAG | Adagene Inc | $78.26M | +545.20% |
| ADVM | Adverum Biotechnologies Inc | $72.40M | +496.88% |
| FENC | Fennec Pharmaceuticals Inc | $71.82M | +492.10% |
| ATHA | Athira Pharma Inc | $71.59M | +490.19% |
| HYPD | Eyenovia Inc | $70.07M | +477.63% |
| ARMP | Armata Pharmaceuticals Inc | $69.80M | +475.43% |
| ACOG | Alpha Cognition Inc | $69.25M | +470.88% |
| KZR | Kezar Life Sciences Inc | $68.00M | +460.59% |
| NBTX | Nanobiotix | $67.76M | +458.62% |
| PMN | ProMIS Neurosciences Inc | $67.41M | +455.74% |
| IRD | Ocuphire Pharma Inc | $66.79M | +450.59% |
| GRCE | Acasti Pharma Inc | $66.65M | +449.50% |
| ALDX | Aldeyra Therapeutics Inc | $66.48M | +448.09% |
| MURA | Mural Oncology plc | $65.76M | +442.11% |
| ALGS | Aligos Therapeutics Inc | $64.56M | +432.22% |
| UNCY | Unicycive Therapeutics Inc | $64.41M | +430.96% |
| PYXS | Pyxis Oncology Inc | $64.30M | +430.09% |
| QTTB | Q32 Bio Inc | $63.67M | +424.94% |
| EQ | Equillium Inc | $63.08M | +420.06% |
| IPHA | Innate Pharma | $62.69M | +416.84% |
| MRSN | Mersana Therapeutics Inc | $62.69M | +416.78% |
| OKUR | Reneo Pharmaceuticals Inc - Class A | $62.12M | +412.09% |
| HOOK | Hookipa Pharma Inc | $61.26M | +405.00% |
| CNTB | Connect Biopharma Holdings Ltd | $60.07M | +395.19% |
| SGMO | Sangamo Therapeutics Inc | $59.97M | +394.35% |
| KLTO | Klotho Neurosciences Inc Com | $59.74M | +392.47% |
| KLTOW | Klotho Neurosciences Inc Wt Exp | $59.74M | +392.47% |
| SPRO | Spero Therapeutics Inc | $59.02M | +386.57% |
| CNTX | Context Therapeutics Inc | $58.86M | +385.24% |
| HOWL | Werewolf Therapeutics Inc | $58.02M | +378.33% |
| LITS | Lite Strategy Inc | $57.79M | +376.41% |
| OCGN | Ocugen Inc | $56.91M | +369.13% |
| ATHE | Alterity Therapeutics Ltd | $56.86M | +368.78% |
| KTTA | Pasithea Therapeutics Corp | $56.35M | +364.59% |
| SPRB | Spruce Biosciences Inc | $56.17M | +363.03% |
| PMCB | PharmaCyte Biotech Inc | $55.87M | +360.62% |
| RLYB | Rallybio Corp | $54.47M | +349.07% |
| COYA | Coya Therapeutics Inc | $53.27M | +339.17% |
| DMAC | DiaMedica Therapeutics Inc | $53.08M | +337.59% |
| LVTX | LAVA Therapeutics NV | $51.91M | +327.99% |
| RANI | Rani Therapeutics Holdings Inc Class A | $51.88M | +327.69% |
| PHXM | PHAXIAM Therapeutics SA ADR | $51.31M | +322.98% |
| INO | Inovio Pharmaceuticals Inc | $49.78M | +310.36% |
| JAGX | Jaguar Health Inc | $49.47M | +307.85% |
| CRDF | Cardiff Oncology Inc | $49.17M | +305.38% |
| IFRX | InflaRx N.V. | $48.94M | +303.47% |
| VTGN | VistaGen Therapeutics Inc | $48.56M | +300.36% |
| BOLT | Bolt Biotherapeutics Inc | $48.03M | +295.94% |
| GRDX | Entero Therapeutics Inc | $47.97M | +295.43% |
| APRE | Aprea Therapeutics Inc | $47.61M | +292.52% |
| BMEA | Biomea Fusion Inc | $46.38M | +282.40% |
| ATNM | Actinium Pharmaceuticals Inc | $45.44M | +274.59% |
| AKTX | Akari Therapeutics Plc | $45.38M | +274.08% |
| ICCC | Immucell Corp | $44.11M | +263.63% |
| QLGN | Qualigen Therapeutics, Inc. Common Stock | $43.47M | +258.37% |
| VERU | Veru Inc | $43.08M | +255.17% |
| MNOV | Medicinova Inc | $42.70M | +252.06% |
| VANI | Vivani Medical Inc | $42.35M | +249.16% |
| ACHV | Achieve Life Sciences Inc | $41.79M | +244.52% |
| MREO | Mereo Biopharma Group Plc | $40.61M | +234.82% |
| IOBT | IO Biotech Inc | $39.96M | +229.40% |
| BLRX | Bioline Rx Ltd | $38.80M | +219.84% |
| VRCA | Verrica Pharmaceuticals Inc | $38.79M | +219.75% |
| TOVX | Theriva Biologics Inc | $38.25M | +215.32% |
| SNTI | Senti Biosciences Inc | $38.24M | +215.26% |
| NXTC | Nextcure Inc | $37.98M | +213.08% |
| ATOS | Atossa Therapeutics Inc | $37.94M | +212.80% |
| PASG | Passage Bio Inc | $36.46M | +200.59% |
| CGTX | Cognition Therapeutics Inc | $36.14M | +197.94% |
| LYRA | Lyra Therapeutics Inc | $36.11M | +197.68% |
| MAIA | MAIA Biotechnology Inc | $35.32M | +191.20% |
| ALLR | Allarity Therapeutics Inc | $34.92M | +187.91% |
| NEUP | Neuphoria Therapeutics Inc | $34.81M | +186.97% |
| APLT | Applied Therapeutics Inc | $34.37M | +183.38% |
| ITRM | Iterum Therapeutics Plc | $32.50M | +167.96% |
| GNLX | Genelux Corp | $32.37M | +166.88% |
| GNTA | Genenta Science SpA | $31.89M | +162.90% |
| CUE | Cue Biopharma Inc | $30.88M | +154.55% |
| CING | Cingulate Inc | $30.86M | +154.42% |
| SLGL | Sol-Gel Technologies Ltd | $29.92M | +146.64% |
| HURA | TuHURA Biosciences Inc | $29.70M | +144.89% |
| CRIS | Curis Inc | $29.69M | +144.73% |
| CSBR | Champions Oncology Inc | $28.45M | +134.52% |
| DARE | Dare Bioscience Inc | $27.83M | +129.42% |
| NCNA | NuCana plc | $27.55M | +127.16% |
| HCWB | HCW Biologics Inc | $27.34M | +125.41% |
| SER | AgeX Therapeutics Inc | $27.30M | +125.05% |
| BCTX | BriaCell Therapeutics Corp - New | $27.07M | +123.18% |
| QNCX | Quince Therapeutics Inc | $26.62M | +119.48% |
| INAB | IN8bio Inc | $26.27M | +116.53% |
| PLUR | Pluri Inc | $26.06M | +114.81% |
| VYNE | VYNE Therapeutics Inc | $25.87M | +113.30% |
| INMB | INmune Bio Inc | $25.82M | +112.84% |
| TVRD | Cara Therapeutics Inc | $25.82M | +112.84% |
| CASI | CASI Pharmaceuticals Inc | $25.65M | +111.46% |
| NVCT | Nuvectis Pharma Inc | $25.40M | +109.38% |
| LPCN | Lipocine Inc | $25.36M | +109.05% |
| PDSB | PDS Biotechnology Corporation | $24.66M | +103.32% |
| RNTX | Rein Therapeutics Inc | $24.16M | +99.16% |
| EVAX | Evaxion Biotech A/S | $23.64M | +94.91% |
| RVPH | Reviva Pharmaceuticals Holdings Inc | $23.56M | +94.23% |
| MBRX | Moleculin Biotech Inc | $23.36M | +92.61% |
| HYFT | MindWalk Holdings Corp | $23.17M | +90.99% |
| CVM | Cel-Sci Corp | $22.89M | +88.74% |
| ELTX | Elicio Therapeutics Inc | $22.69M | +87.05% |
| PYPD | Polypid Ltd | $22.31M | +83.90% |
| OTLK | Outlook Therapeutics Inc | $21.89M | +80.48% |
| PLRZ | Polyrizon Ltd | $21.44M | +76.73% |
| KPRX | Kiora Pharmaceuticals Inc | $21.23M | +75.00% |
| LGVN | Longeveron Inc - Class A | $21.21M | +74.86% |
| JSPR | Jasper Therapeutics Inc | $21.18M | +74.64% |
| MENS | Jyong Biotech Ltd | $20.78M | +71.29% |
| GNPX | Genprex Inc | $20.31M | +67.41% |
| LPTX | Leap Therapeutics Inc | $20.04M | +65.23% |
| ATRA | Atara Biotherapeutics Inc | $20.00M | +64.86% |
| PSTV | Plus Therapeutics Inc | $19.92M | +64.19% |
| APVO | Aptevo Therapeutics Inc | $19.90M | +64.07% |
| COEP | Coeptis Therapeutics Holdings Inc. Common Stock | $19.79M | +63.12% |
| ABVC | ABVC BioPharma Inc | $19.73M | +62.68% |
| SKYE | Skye Bioscience Inc | $19.42M | +60.07% |
| GANX | Gain Therapeutics Inc | $18.74M | +54.48% |
| APM | Aptorum Group Limited Class A Ordinary Shares | $18.69M | +54.09% |
| TTRX | Turn Therapeutics Inc | $18.64M | +53.70% |
| GLMD | Galmed Pharmaceuticals Ltd | $18.63M | +53.56% |
| BYSI | BeyondSpring Inc | $18.41M | +51.74% |
| BDRX | Biodexa Pharmaceuticals Plc | $18.15M | +49.60% |
| EVGN | Evogene Ltd | $17.95M | +47.96% |
| BIVI | BioVie Inc - Class A | $17.51M | +44.39% |
| MRKR | Marker Therapeutics Inc | $17.43M | +43.73% |
| PHIO | Phio Pharmaceuticals Corp | $17.41M | +43.54% |
| IBO | Impact BioMedical Inc | $17.09M | +40.86% |
| MBIO | Mustang Bio Inc | $16.58M | +36.70% |
| ANVS | Annovis Bio Inc | $16.24M | +33.91% |
| GALT | Galectin Therapeutics Inc | $15.76M | +29.92% |
| QNRX | Quoin Pharmaceuticals Ltd | $15.69M | +29.37% |
| ONCT | Oncternal Therapeutics Inc | $15.60M | +28.62% |
| IMRN | Immuron Ltd | $15.12M | +24.67% |
| CRVO | CervoMed Inc | $15.11M | +24.59% |
| PPCB | Propanc Biopharma Inc | $15.11M | +24.58% |
| REVB | Revelation Biosciences Inc | $15.04M | +24.03% |
| CLRB | Cellectar Biosciences Inc | $14.98M | +23.48% |
| QNTM | FSD Pharma Inc - Class B - Class B (Sub Voting) | $14.98M | +23.46% |
| ELAB | PMGC Holdings Inc | $14.94M | +23.15% |
| SONN | Sonnet BioTherapeutics Holdings Inc | $14.88M | +22.71% |
| ANIX | Anixa Biosciences Inc | $14.87M | +22.55% |
| ONCO | Onconetix Inc | $14.83M | +22.28% |
| SYBX | Synlogic Inc | $14.61M | +20.45% |
| CMND | Clearmind Medicine Inc | $14.52M | +19.73% |
| MTVA | MetaVia Inc | $14.39M | +18.62% |
| LSTA | Lisata Therapeutics Inc | $14.06M | +15.90% |
| RNXT | RenovoRx Inc | $13.96M | +15.12% |
| ADTX | Aditxt Inc | $13.91M | +14.65% |
| CMMB | Chemomab Therapeutics Ltd | $13.81M | +13.87% |
| YDES | YD Bio Ltd | $13.78M | +13.60% |
| PTN | Palatin Technologies Inc | $13.23M | +9.03% |
| ENTX | Entera Bio Ltd | $13.13M | +8.24% |
| PBM | Psyence Biomedical Ltd | $12.81M | +5.61% |
| XCUR | Exicure Inc | $12.76M | +5.15% |
| ARTL | Artelo Biosciences Inc | $12.52M | +3.20% |
| EDSA | Edesa Biotech Inc | $12.38M | +2.10% |
| KALA | Kala Bio Inc | $12.32M | +1.55% |
| INTS | Intensity Therapeutics Inc | $12.29M | +1.33% |
| NRXP | NRX Pharmaceuticals Inc | $11.90M | -1.87% |
| CLSD | Clearside Biomedical, Inc. Common Stock | $11.64M | -4.03% |
| SCNI | Scinai Immunotherapeutics Ltd | $11.63M | -4.15% |
| NCEL | NLS Pharmaceutics Ltd | $11.45M | -5.65% |
| GRI | GRI Bio Inc | $11.34M | -6.52% |
| ICU | SeaStar Medical Holding Corp | $11.26M | -7.15% |
| TPST | Tempest Therapeutics Inc | $10.75M | -11.39% |
| ERNA | Ernexa Therapeutics Inc | $10.54M | -13.08% |
| GLSI | Greenwich LifeSciences Inc | $10.51M | -13.39% |
| INKT | MiNK Therapeutics Inc | $10.38M | -14.45% |
| NNVC | NanoViricides Inc | $10.22M | -15.75% |
| HIND | ReShape Lifesciences Inc | $10.19M | -16.03% |
| LNAI | Lunai Bioworks Inc | $9.86M | -18.71% |
| CLDI | Calidi Biotherapeutics Inc | $9.59M | -20.93% |
| CDIO | Cardio Diagnostics Holdings Inc | $9.56M | -21.19% |
| ACXP | Acurx Pharmaceuticals Inc | $9.54M | -21.35% |
| CANF | Can-Fite Biopharma Ltd | $9.51M | -21.57% |
| ANEB | Anebulo Pharmaceuticals, Inc. Common Stock | $9.42M | -22.32% |
| IGC | IGC Pharma Inc | $9.19M | -24.28% |
| CLGN | CollPlant Biotechnologies Ltd New | $9.18M | -24.30% |
| ACTU | Actuate Therapeutics Inc | $8.91M | -26.54% |
| NRXS | Neuraxis Inc | $8.75M | -27.90% |
| AEON | AEON Biopharma Inc - Class A | $8.63M | -28.85% |
| CALC | CalciMedica Inc | $8.61M | -29.03% |
| AIM | AIM ImmunoTech Inc. | $8.59M | -29.23% |
| BCAB | BioAtla Inc | $8.57M | -29.38% |
| CDT | CDT Equity Inc | $8.55M | -29.50% |
| CYCN | Cyclerion Therapeutics Inc | $8.51M | -29.88% |
| SLRX | Decoy Therapeutics Inc | $8.42M | -30.56% |
| CURX | Curanex Pharmaceuticals Inc | $8.41M | -30.66% |
| ONCY | Oncolytics Biotech Inc | $8.16M | -32.72% |
| TRAW | Traws Pharma Inc | $8.16M | -32.76% |
| IMNN | Imunon Inc | $8.02M | -33.89% |
| GDTC | CytoMed Therapeutics Ltd | $7.98M | -34.17% |
| XBIO | Xenetic Biosciences Inc | $7.91M | -34.80% |
| DYAI | Dyadic International Inc DE | $7.81M | -35.62% |
| BGMS | Bio Green Med Solution Inc | $7.56M | -37.64% |
| OGEN | Oragenics Inc | $7.49M | -38.26% |
| DRMA | Dermata Therapeutics Inc | $7.47M | -38.45% |
| COCP | Cocrystal Pharma Inc | $7.43M | -38.78% |
| VIVS | VivoSim Labs Inc | $7.39M | -39.11% |
| TELO | Telomir Pharmaceuticals Inc | $7.34M | -39.48% |
| OSTX | OS Therapies Inc | $7.30M | -39.82% |
| LTRN | Lantern Pharma Inc | $7.22M | -40.45% |
| ASBP | Aspire Biopharma Holdings Inc | $7.12M | -41.33% |
| SILO | SILO Pharma Inc | $7.02M | -42.14% |
| SNGX | Soligenix Inc | $6.92M | -42.93% |
| NTRB | Nutriband Inc | $6.89M | -43.18% |
| INDP | Indaptus Therapeutics Inc | $6.84M | -43.61% |
| SXTP | 60 Degrees Pharmaceuticals Inc | $6.76M | -44.24% |
| GTBP | GT Biopharma Inc | $6.76M | -44.28% |
| APLM | Apollomics Inc - Class A | $6.71M | -44.65% |
| CELZ | Creative Medical Technology Holdings Inc | $6.44M | -46.90% |
| FBLG | FibroBiologics Inc | $5.94M | -51.05% |
| MTNB | Matinas Biopharma Holdings Inc | $5.87M | -51.57% |
| KAPA | Kairos Pharma Ltd | $5.74M | -52.65% |
| VRAX | Virax Biolabs Group Ltd - Class A | $5.72M | -52.89% |
| HOTH | Hoth Therapeutics Inc | $5.59M | -53.88% |
| ENVB | Enveric Biosciences Inc | $5.52M | -54.48% |
| ADIL | Adial Pharmaceuticals Inc | $5.23M | -56.91% |
| BBLG | Bone Biologics Corp | $4.98M | -58.95% |
| TVGN | Tevogen Bio Holdings Inc | $4.92M | -59.43% |
| LEXX | Lexaria Bioscience Corp | $4.78M | -60.58% |
| ADXN | Addex Therapeutics Ltd | $4.76M | -60.77% |
| CNSP | Cns Pharmaceuticals Inc | $4.65M | -61.64% |
| OKYO | OKYO Pharma Ltd - New | $4.64M | -61.72% |
| BRTX | BioRestorative Therapies Inc | $4.64M | -61.75% |
| SLXN | Silexion Therapeutics Corp | $4.60M | -62.06% |
| PCSA | Processa Pharmaceuticals Inc | $4.52M | -62.73% |
| PULM | Pulmatrix Inc | $4.50M | -62.93% |
| PTIX | Protagenic Therapeutics Inc | $4.43M | -63.47% |
| ALZN | Alzamend Neuro Inc | $4.04M | -66.68% |
| EXOZ | Invizyne Technologies Inc | $4.02M | -66.87% |
| JUNS | Jupiter Neurosciences Inc | $3.95M | -67.45% |
| ESLA | Estrella Immunopharma Inc | $3.66M | -69.85% |
| NTHI | NeOnc Technologies Holdings Inc | $3.33M | -72.55% |
| TTNP | Titan Pharmaceuticals Inc (de) | $3.05M | -74.85% |
| GOVX | Geovax Labs Inc | $2.98M | -75.41% |
| CVKD | Cadrenal Therapeutics Inc | $2.86M | -76.41% |
| LIMN | Liminatus Pharma Inc | $2.79M | -77.00% |
| ENSC | Ensysce Biosciences Inc | $2.17M | -82.13% |
| XRTX | XORTX Therapeutics Inc | $2.15M | -82.26% |
| TCRT | Alaunos Therapeutics Inc | $1.88M | -84.48% |
| BCDA | BioCardia Inc | $1.71M | -85.89% |
| ABP | Abpro Holdings, Inc Common Stock | $1.06M | -91.24% |
| NRSN | NeuroSense Therapeutics Ltd | $1.03M | -91.53% |
| BCLI | Brainstorm Cell Therapeutics Inc | $755000.00 | -93.78% |
| ZVSA | ZyVersa Therapeutics Inc | $742223.00 | -93.88% |