| IBBQ | INVESCO NASDAQ BIOTECHNOLOGY ETF | $73M | 0.19% | Jun 11, 2021 | 83.93% |
| BBH | VANECK BIOTECH ETF | $396M | 0.35% | Dec 20, 2011 | 58.66% |
| BIB | PROSHARES ULTRA NASDAQ BIOTECHNOLOGY | $84M | N/A | Apr 6, 2010 | 49.76% |
| XBI | STATE STREET(R) SPDR(R) S&P(R) BIOTECH ETF | $11B | 0.35% | Jan 31, 2006 | 40.68% |
| FBT | FIRST TRUST NYSE ARCA BIOTECHNOLOGY INDEX FUND | $2.80B | 0.55% | Jun 19, 2006 | 40.10% |
| PBE | INVESCO BIOTECHNOLOGY & GENOME ETF | $278M | 0.58% | Jun 23, 2005 | 38.30% |
| BBP | VIRTUS BIOTECH ETF | $87M | 0.34% | Dec 16, 2014 | 35.77% |
| FTXH | FIRST TRUST NASDAQ PHARMACEUTICALS ETF | $36M | 0.60% | Sep 20, 2016 | 34.50% |
| TBXU | Trust Direxion Daily Biotech Top 5 Bull 2X ETF | $3M | N/A | Sep 30, 2025 | 31.33% |
| WDNA | WISDOMTREE BIOREVOLUTION FUND | $3M | 0.45% | Jun 1, 2021 | 29.94% |
| FMED | FIDELITY DISRUPTIVE MEDICINE ETF | $46M | 0.50% | Apr 16, 2020 | 28.23% |
| LABU | DIREXION DAILY S&P BIOTECH BULL 3X SHARES DIREXION DAILY S&P BIOTECH BULL 3X SHARES | $678M | N/A | May 28, 2015 | 27.77% |
| HELX | FRANKLIN GENOMIC ADVANCEMENTS ETF | $28M | 0.50% | Feb 25, 2020 | 26.64% |
| BMED | BlackRock Future Health ETF | $11M | 0.55% | Sep 29, 2020 | 25.87% |
| FXH | FIRST TRUST HEALTH CARE ALPHADEX FUND | $959M | 0.61% | May 8, 2007 | 24.71% |
| MEDI | HARBOR HEALTH CARE ETF | $43M | 0.80% | Nov 16, 2022 | 22.74% |
| HTEC | ROBO GLOBAL(R) HEALTHCARE TECHNOLOGY AND INNOVATION ETF | $60M | 0.68% | Jun 24, 2019 | 20.57% |
| PBPH | Portfolio Building Block World Pharma and Biotech Index ETF | $859M | 0.13% | Nov 25, 2025 | 20.46% |
| GNOM | GLOBAL X GENOMICS & BIOTECHNOLOGY ETF | $77M | 0.50% | Apr 5, 2019 | 20.42% |
| HRTS | TEMA HEART & HEALTH ETF | $54M | 0.75% | Nov 20, 2023 | 19.01% |
| IDNA | ISHARES GENOMICS IMMUNOLOGY AND HEALTHCARE ETF | $194M | 0.47% | Jun 11, 2019 | 18.34% |
| VHT | VANGUARD HEALTH CARE INDEX FUND ETF SHARES | $20B | 0.09% | Jan 26, 2004 | 17.86% |
| PTH | INVESCO DORSEY WRIGHT HEALTHCARE MOMENTUM ETF | $135M | 0.60% | Oct 12, 2006 | 17.75% |
| CANC | TEMA ONCOLOGY ETF | $190M | 0.75% | Aug 14, 2023 | 17.52% |
| GDOC | GOLDMAN SACHS FUTURE HEALTH CARE EQUITY ETF | $19M | 0.75% | Nov 9, 2021 | 17.27% |
| QQQJ | INVESCO NASDAQ NEXT GEN 100 ETF | $1.10B | 0.15% | Oct 13, 2020 | 17.21% |
| PJP | INVESCO PHARMACEUTICALS ETF | $356M | 0.57% | Jun 23, 2005 | 17.18% |
| IYH | ISHARES U.S. HEALTHCARE ETF | $3.20B | 0.38% | Jun 12, 2000 | 16.67% |
| PWS | PACER WEALTHSHIELD ETF | $25M | 0.60% | Dec 11, 2017 | 16.55% |
| IWO | ISHARES RUSSELL 2000 GROWTH ETF | $15B | 0.24% | Jul 24, 2000 | 15.57% |
| BBC | VIRTUS BIOTECH CLINICAL TRIALS ETF | $53M | 0.65% | Dec 16, 2014 | 14.24% |
| AGNG | GLOBAL X AGING POPULATION ETF | $85M | 0.50% | May 9, 2016 | 14.17% |
| MEDX | HORIZON KINETICS MEDICAL ETF | $19M | 0.85% | Sep 30, 1999 | 13.93% |
| RSPH | INVESCO S&P 500 EQUAL WEIGHT HEALTH CARE ETF | $705M | 0.40% | Nov 1, 2006 | 13.83% |
| FHLC | FIDELITY MSCI HEALTH CARE INDEX ETF | $3.20B | 0.08% | Oct 21, 2013 | 12.66% |
| FSEG | FIDELITY ENHANCED SMALL CAP GROWTH ETF | $6M | 0.28% | Apr 28, 2026 | 12.56% |
| IBRN | ISHARES NEUROSCIENCE AND HEALTHCARE ETF | $6M | 0.47% | Aug 24, 2022 | 12.37% |
| ESSC | EVENTIDE SMALL CAP ETF | $30M | 0.49% | Sep 29, 2025 | 11.63% |
| MMSC | FIRST TRUST MULTI-MANAGER SMALL CAP OPPORTUNITIES ETF | $55M | 0.95% | Oct 13, 2021 | 11.34% |
| TRUH | VANECK HEALTHCARE TRUSECTOR ETF | $1M | 0.10% | Apr 1, 2026 | 11.05% |
| QFRD | PACER S&P 500 QUALITY FCF R&D LEADERS ETF | $1M | 0.49% | Jan 12, 2026 | 10.99% |
| ACSG | AMERICAN CENTURY SMALL CAP GROWTH INSIGHTS ETF | $25M | 0.49% | Oct 14, 2025 | 10.92% |
| JDOC | JPMORGAN HEALTHCARE LEADERS ETF | $9M | 0.65% | Nov 1, 2023 | 10.92% |
| XLV | STATE STREET(R) HEALTH CARE SELECT SECTOR SPDR(R) ETF | $41B | 0.08% | Dec 16, 1998 | 10.88% |
| THNR | Amplify Weight Loss Drug & Treatment ETF | $4M | 0.59% | May 20, 2024 | 10.72% |
| FNY | FIRST TRUST MID CAP GROWTH ALPHADEX FUND | $615M | 0.73% | Apr 19, 2011 | 10.56% |
| TMFX | MOTLEY FOOL NEXT INDEX ETF | $34M | 0.50% | Dec 30, 2021 | 10.54% |
| TNXT | T. ROWE PRICE INNOVATION LEADERS ETF | $18M | 0.49% | Jan 28, 2026 | 10.50% |
| VFMO | VANGUARD U.S. MOMENTUM FACTOR ETF ETF SHARES | $2B | 0.13% | Feb 13, 2018 | 10.46% |
| QNXT | ISHARES NASDAQ-100 EX TOP 30 ETF | $19M | 0.20% | Oct 23, 2024 | 10.37% |
| FESM | FIDELITY ENHANCED SMALL CAP ETF | $5.80B | 0.28% | Dec 20, 2007 | 10.05% |
| VBK | VANGUARD SMALL-CAP GROWTH INDEX FUND ETF SHARES | $47B | 0.05% | Jan 26, 2004 | 10.03% |
| GURU | GLOBAL X GURU INDEX ETF | $64M | 0.75% | Jun 4, 2012 | 9.81% |
| ARKG | ARK GENOMIC REVOLUTION ETF | $1.70B | 0.75% | Oct 31, 2014 | 9.53% |
| QQXT | FIRST TRUST NASDAQ-100 EX-TECHNOLOGY SECTOR INDEX FUND | $166M | 0.57% | Feb 8, 2007 | 9.30% |
| IQSM | NYLI CANDRIAM U.S. MID CAP EQUITY ETF | $337M | 0.15% | Oct 24, 2022 | 9.21% |
| PINK | SIMPLIFY HEALTH CARE ETF | $359M | 0.51% | Oct 7, 2021 | 9.16% |
| RSSL | GLOBAL X RUSSELL 2000 ETF | $1.50B | 0.08% | Jun 4, 2024 | 9.04% |
| TMSL | T. ROWE PRICE SMALL-MID CAP ETF | $2.70B | 0.55% | Jun 14, 2023 | 8.93% |
| SBIO | ALPS MEDICAL BREAKTHROUGHS ETF | $190M | 0.50% | Dec 30, 2014 | 8.82% |
| VTWG | VANGUARD RUSSELL 2000 GROWTH INDEX FUND ETF SHARES | $1.80B | 0.06% | Sep 20, 2010 | 8.81% |
| TAX | CAMBRIA TAX AWARE ETF | $26M | 0.54% | Dec 17, 2024 | 8.77% |
| SAMM | STRATEGAS MACRO MOMENTUM ETF | $30M | 0.65% | Apr 4, 2024 | 8.69% |
| BBSC | JPMORGAN BETABUILDERS U.S. SMALL CAP EQUITY ETF | $744M | 0.09% | Nov 16, 2020 | 8.48% |
| FEMG | FIDELITY ENHANCED MID CAP GROWTH ETF | $7M | 0.23% | Apr 28, 2026 | 8.30% |
| DRUP | Graniteshares Nasdaq Select Disruptors ETF | $47M | 0.60% | Oct 7, 2019 | 8.28% |
| SMLF | ISHARES U.S. SMALL-CAP EQUITY FACTOR ETF | $4.20B | 0.15% | Apr 28, 2015 | 8.14% |
| IXJ | ISHARES GLOBAL HEALTHCARE ETF | $3.80B | 0.40% | Nov 13, 2001 | 8.10% |
| GSSC | GOLDMAN SACHS ACTIVEBETA(R) U.S. SMALL CAP EQUITY ETF | $1.10B | 0.20% | Jun 28, 2017 | 8.05% |
| RXL | ProShares Ultra Health Care 2X Shares | $79M | N/A | Jan 30, 2007 | 7.75% |
| ISCG | ISHARES MORNINGSTAR SMALL-CAP GROWTH ETF | $1B | 0.06% | Jun 28, 2004 | 7.72% |
| RUSC | RUSSELL INVESTMENTS U.S. SMALL CAP EQUITY ETF | $79M | 0.64% | May 13, 2025 | 7.68% |
| VTWO | VANGUARD RUSSELL 2000 INDEX FUND ETF SHARES | $19B | 0.06% | Sep 20, 2010 | 7.57% |
| GSC | GOLDMAN SACHS SMALL CAP CORE EQUITY ETF | $300M | 0.75% | Oct 3, 2023 | 7.48% |
| FFTY | INNOVATOR IBD(R) 50 ETF | $94M | 0.80% | Apr 8, 2015 | 7.43% |
| MID | AMERICAN CENTURY MID CAP GROWTH IMPACT ETF | $101M | 0.45% | Jul 15, 2020 | 7.42% |
| LFSC | F/M EMERALD LIFE SCIENCES INNOVATION ETF | $122M | 0.54% | Oct 30, 2024 | 7.37% |
| CURE | DIREXION DAILY HEALTHCARE BULL 3X SHARES | $169M | N/A | Jun 15, 2011 | 7.35% |
| FAD | FIRST TRUST MULTI CAP GROWTH ALPHADEX FUND | $580M | 0.63% | May 8, 2007 | 7.29% |
| BUL | PACER US CASH COWS GROWTH ETF | $127M | 0.60% | May 2, 2019 | 7.25% |
| EKG | FIRST TRUST NASDAQ LUX DIGITAL HEALTH SOLUTIONS ETF | $3M | 0.65% | Mar 22, 2022 | 7.24% |
| FDG | AMERICAN CENTURY FOCUSED DYNAMIC GROWTH ETF | $408M | 0.45% | Mar 31, 2020 | 7.19% |
| RKSG | RUK STRATEGIC GROWTH ETF | $2M | 0.50% | Apr 6, 2026 | 7.15% |
| COWG | PACER US LARGE CAP CASH COWS GROWTH LEADERS ETF | $2.40B | 0.49% | Dec 21, 2022 | 7.14% |
| ILDR | FIRST TRUST INNOVATION LEADERS ETF | $302M | 0.75% | May 25, 2021 | 7.02% |
| STXK | STRIVE SMALL-CAP ETF | $84M | 0.18% | Nov 9, 2022 | 7.00% |
| MFIG | MOTLEY FOOL INNOVATIVE GROWTH FACTOR ETF | $12M | 0.50% | Dec 8, 2025 | 6.97% |
| XMHQ | INVESCO S&P MIDCAP QUALITY ETF | $5.40B | 0.25% | Dec 1, 2006 | 6.94% |
| QMID | WISDOMTREE U.S. MIDCAP QUALITY GROWTH FUND | $2M | 0.38% | Jan 23, 2024 | 6.85% |
| QMOM | ALPHA ARCHITECT U.S. QUANTITATIVE MOMENTUM ETF | $444M | 0.28% | Dec 1, 2015 | 6.79% |
| MDYG | STATE STREET(R) SPDR(R) S & P 400(TM) MID CAP GROWTH ETF | $2.90B | 0.15% | Nov 8, 2005 | 6.78% |
| IJK | ISHARES S&P MID-CAP 400 GROWTH ETF | $11B | 0.17% | Jul 24, 2000 | 6.66% |
| ISCB | ISHARES MORNINGSTAR SMALL-CAP ETF | $287M | 0.04% | Jun 28, 2004 | 6.58% |
| AVIE | AVANTIS INFLATION FOCUSED EQUITY ETF | $10M | 0.25% | Sep 27, 2022 | 6.56% |
| SAGP | STRATEGAS GLOBAL POLICY OPPORTUNITIES ETF | $77M | 0.65% | Jan 25, 2022 | 6.55% |
| LSGR | NATIXIS LOOMIS SAYLES FOCUSED GROWTH ETF | $839M | 0.59% | Jun 29, 2023 | 6.50% |
| SGRW | HARBOR ACTIVE SMALL CAP GROWTH ETF | $5M | 0.80% | Jan 14, 2026 | 6.49% |
| ESML | ISHARES ESG AWARE MSCI USA SMALL-CAP ETF | $2.90B | 0.17% | Apr 10, 2018 | 6.46% |
| IVOG | VANGUARD S&P MID-CAP 400 GROWTH INDEX FUND ETF SHARES | $1.90B | 0.10% | Sep 7, 2010 | 6.40% |
| TECB | ISHARES U.S. TECH BREAKTHROUGH MULTISECTOR ETF | $478M | 0.30% | Jan 8, 2020 | 6.34% |
| ABOT | ABACUS FCF INNOVATION LEADERS ETF | $5M | 0.39% | Dec 7, 2020 | 6.34% |
| FYC | FIRST TRUST SMALL CAP GROWTH ALPHADEX FUND | $1.30B | 0.70% | Apr 19, 2011 | 6.33% |
| QQQG | PACER NASDAQ 100 TOP 50 CASH COWS GROWTH LEADERS ETF | $22M | 0.49% | Aug 19, 2024 | 6.16% |
| IWN | ISHARES RUSSELL 2000 VALUE ETF | $15B | 0.24% | Jul 24, 2000 | 6.14% |
| BKMC | BNY MELLON US MID CAP CORE EQUITY ETF | $670M | 0.04% | Apr 7, 2020 | 6.12% |
| UWM | PROSHARES ULTRA RUSSELL2000 | $279M | N/A | Jan 23, 2007 | 6.07% |
| RND | FIRST TRUST BLOOMBERG R&D LEADERS ETF | $5M | 0.60% | Apr 30, 2024 | 6.01% |
| KONG | FORMIDABLE FORTRESS ETF | $22M | 0.89% | Jul 21, 2021 | 5.99% |
| SDG | iShares MSCI Global Sustainable Development Goals ETF | $170M | 0.50% | Apr 20, 2016 | 5.96% |
| GRNJ | FUNDSTRAT GRANNY SHOTS US SMALL- & MID-CAP ETF | $503M | 0.75% | Nov 17, 2025 | 5.96% |
| RFG | INVESCO S&P MIDCAP 400 PURE GROWTH ETF | $359M | 0.35% | Mar 1, 2006 | 5.92% |
| TCAF | T. ROWE PRICE CAPITAL APPRECIATION EQUITY ETF | $7.40B | 0.31% | Jun 14, 2023 | 5.89% |
| SXQG | ETC 6 MERIDIAN QUALITY GROWTH ETF | $63M | 0.55% | May 10, 2021 | 5.78% |
| QQEW | FIRST TRUST NASDAQ-100 SELECT EQUAL WEIGHT ETF | $1.80B | 0.55% | Apr 19, 2006 | 5.76% |
| GPT | INTELLIGENT ALPHA ATLAS ETF | $24M | 0.69% | Sep 17, 2024 | 5.75% |
| SCHA | SCHWAB U.S. SMALL-CAP ETF | $24B | 0.03% | Nov 3, 2009 | 5.72% |
| PRFZ | INVESCO FTSE RAFI US 1500 SMALL-MID ETF | $2.90B | 0.34% | Sep 20, 2006 | 5.58% |
| CGMM | CAPITAL GROUP U.S. SMALL AND MID CAP ETF SHARE CLASS | $3.10B | 0.51% | Jan 14, 2025 | 5.58% |
| STXM | STRIVE MID-CAP ETF | $22M | 0.18% | Apr 10, 2024 | 5.57% |
| XOVR | ERSHARES PRIVATE-PUBLIC CROSSOVER ETF | $2.20B | 0.75% | Nov 7, 2017 | 5.55% |
| VTWV | VANGUARD RUSSELL 2000 VALUE INDEX FUND ETF SHARES | $1.40B | 0.06% | Sep 20, 2010 | 5.46% |
| JSMD | JANUS HENDERSON SMALL/MID CAP GROWTH ALPHA ETF | $1.10B | 0.30% | Feb 23, 2016 | 5.41% |
| DWAS | INVESCO DORSEY WRIGHT SMALLCAP MOMENTUM ETF | $455M | 0.60% | Jul 19, 2012 | 5.40% |
| GRPM | INVESCO S&P MIDCAP 400 GARP ETF | $473M | 0.35% | Dec 3, 2010 | 5.36% |
| TSNF | Truth Social American Next Frontiers ETF | $10M | 0.65% | Dec 29, 2025 | 5.22% |
| VXF | VANGUARD EXTENDED MARKET INDEX FUND ETF SHARES | $98B | 0.05% | Dec 27, 2001 | 5.21% |
| JSML | JANUS HENDERSON SMALL CAP GROWTH ALPHA ETF | $450M | 0.30% | Feb 23, 2016 | 5.20% |
| LST | LEUTHOLD SELECT INDUSTRIES ETF | $120M | 0.65% | Jun 19, 2000 | 5.19% |
| QQQE | DIREXION NASDAQ-100(R) EQUAL WEIGHTED INDEX SHARES | $1.40B | 0.35% | Mar 21, 2012 | 5.16% |
| SCHM | SCHWAB U.S. MID-CAP ETF | $15B | 0.03% | Jan 13, 2011 | 5.16% |
| ARKK | ARK INNOVATION ETF | $6.50B | 0.75% | Oct 31, 2014 | 5.08% |
| PSC | Principal U.S. Small-Cap ETF | $2.30B | 0.38% | Sep 21, 2016 | 5.07% |
| SCDS | JPMORGAN FUNDAMENTAL DATA SCIENCE SMALL CORE ETF | $9M | 0.40% | Aug 7, 2024 | 5.04% |